Detailed information of TA system TA196569

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/-
• Location: 3119047..3119509
• Replicon: chromosome
• Accession: NZ_CP071586
• Organism: Pseudomonas germanica strain FIT28

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: J0G10_RS13920
• Protein ID: WP_245398055.1
• Coordinates: 3119047..3119268 (-)
• Length: 74 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: J0G10_RS13925
• Protein ID: WP_095049843.1
• Coordinates: 3119315..3119509 (-)
• Length: 65 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
J0G10_RS13920 (J0G10_13930)	3119047..3119268	-	222	WP_245398055.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
J0G10_RS13925 (J0G10_13935)	3119315..3119509	-	195	WP_095049843.1	stability determinant	Antitoxin
J0G10_RS13930 (J0G10_13940)	3119812..3120759	-	948	WP_095049844.1	transporter	-
J0G10_RS13935 (J0G10_13945)	3120970..3122067	+	1098	WP_220558710.1	AraC family transcriptional regulator	-
J0G10_RS13940 (J0G10_13950)	3122385..3123272	+	888	WP_095126454.1	Dyp-type peroxidase	-
J0G10_RS13945 (J0G10_13955)	3123283..3124251	+	969	WP_220558711.1	Gfo/Idh/MocA family oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-74)

Sequences

Toxin

Protein

• Length: 74 a.a.
• Molecular weight: 8253.45 Da
• Isoelectric Point: 11.7356

>T196569 WP_245398055.1 NZ_CP071586:c3119268-3119047 [Pseudomonas germanica]
IEQYNSNASAALQRKVGAATQRLSSIPYGHRSGRVPGTREMVVNPNYLLVYRVNGRIKILTLVHTRQQYPRTS

Nucleotide

• Length: 222 bp

>T196569 NZ_CP095162:c1989109-1988852 [Streptococcus suis]
ATGGGAATCCATTTTACAGAGGATGCCTGGGAAGACTATCTTTATTGGCAAGGTCAGGATAAGAAAACACTCAAGCGAAT
CAATAAGATTATCAAGGATATGCAACGACATCCTTTTGAAGGCATTGCCAAACCAGAACCCTTGAAGTATGATTATCAGG
GTGCCTGGTCTCGGAGAATTGATGCCGAAAATCGGCTGATTTATATGGTAGAAGTAGATAAGCTGTATATTTTGTCTTTA
AAGGATCATTATGGGTGA

Antitoxin

Protein

• Length: 65 a.a.
• Molecular weight: 7554.45 Da
• Isoelectric Point: 4.6258

>AT196569 WP_095049843.1 NZ_CP071586:c3119509-3119315 [Pseudomonas germanica]
MSILLSPFYSEFESEEEAESYDRWFRAKVQAALDDPRPGIPHEEAMVRLDQLLEEKRKNRRTAA

Nucleotide

• Length: 195 bp

>AT196569 NZ_CP095162:c1989371-1989111 [Streptococcus suis]
ATGGAAGCTATTGTATATTCCCATTTTCGAAATCACTTAAAGGACTATATGAAAAAGGTCAATGACGAGTTTGAACCTTT
GGTCGTGGTTAATAAAAATCCAGAGGAAGATATTGTTGTACTCTCAAAGAGTGAGTGGGATAGTTTACAAGAAACCCTCG
CTGTTGCTCGGAACACTTATCTGTCTCAAAAAGTCCTACGTGGTATGGCTAAAGTCAAAACGGGACAAACCCAAGAACGA
AACCTGATAGAGGCGGACTAA