Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 956073..956669 Replicon chromosome
Accession NZ_CP071586
Organism Pseudomonas germanica strain FIT28

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag J0G10_RS04120 Protein ID WP_095126118.1
Coordinates 956367..956669 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag J0G10_RS04115 Protein ID WP_095126119.1
Coordinates 956073..956363 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J0G10_RS04095 (J0G10_04095) 952375..954495 - 2121 WP_220557532.1 TonB-dependent copper receptor -
J0G10_RS04100 (J0G10_04100) 954581..955027 - 447 WP_220557534.1 DUF2946 domain-containing protein -
J0G10_RS04105 (J0G10_04105) 955049..955528 - 480 WP_095047344.1 copper chaperone PCu(A)C -
J0G10_RS04110 (J0G10_04110) 955577..955975 - 399 WP_095047345.1 DUF2946 domain-containing protein -
J0G10_RS04115 (J0G10_04115) 956073..956363 - 291 WP_095126119.1 putative addiction module antidote protein Antitoxin
J0G10_RS04120 (J0G10_04120) 956367..956669 - 303 WP_095126118.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J0G10_RS04125 (J0G10_04125) 956841..957557 - 717 WP_220557536.1 cobalt-precorrin-6A reductase -
J0G10_RS04130 (J0G10_04130) 957554..958651 - 1098 WP_095047347.1 cobalt-precorrin-5B (C(1))-methyltransferase -
J0G10_RS04135 (J0G10_04135) 958644..959855 - 1212 WP_220557538.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE -
J0G10_RS04140 (J0G10_04140) 959988..961283 + 1296 WP_281062911.1 precorrin-3B synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Uncharacterized protein HI1420

(4-95)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11534.24 Da        Isoelectric Point: 9.7107

>T196566 WP_095126118.1 NZ_CP071586:c956669-956367 [Pseudomonas germanica]
MISFERSRIFSEWLDSLKDIKGKGRIISRIKTAEHGNFGDCGFVGDTVYEMRVHYGPGYRMYFTRKGEVIYLLLIGGDKS
TQKRDIKRAVQMAHNIGNEE

Download         Length: 303 bp

>T196566 NZ_CP095162:c1210657-1209380 [Streptococcus suis]
ATGGCAAATATAGTCAATTTTACTGACAAACAATTTGAGAATCGCTTAAATGATAATTTAGAAGAATTGATTCAAGGAAA
AAAAGCGGTTGAATCGCCAACCGCTTTTTTACTTGGTGGGCAACCAGGGTCAGGGAAAACCAGTTTGCGATCAGCAATTT
TTGAAGAAACACAAGGGAATGTTATTGTCATTGATAATGATACCTTTAAACAACAGCACCCTAATTTTGATGAACTAGTG
AAGCTTTATGAAAAAGACGTAGTAAAACACGTTACCCCTTATTCTAATCGCATGACAGAAGCGATCATAAGCCGTTTGAG
CGATCAAGGGTATAATTTGGTGATCGAAGGTACAGGACGAACAACAGACGTTCCTATTCAAACCGCAACAATGCTTCAAT
CTAAAGGTTATGAAACAAAAATATACGTCATGGCAGTACCGAAAATTGAATCATACTTAGGAACAATTGAACGATATGAA
ACCATGTATGCAGATGATCCAATGACAGCCAGGGCAACACCAAAACAAGCGCATGATATTGTTGTCAAAAACTTACCGAC
CAATTTAGAAACCCTTCATAAAACGGGCTTATTTAGCGATATAAGGCTTTACAATAGAGAAGGAGTGAAACTCTATTCAA
GCTTAGAAACGCCTTCCATTAGTCCGAAAGAGACCTTAGAAAGAGAATTAAATCGTAAAGTATCAGGGAAAGAAATTCAA
CCGACTTTGGAGAGAATAGAGCAAAAAATGGTTCAAAATCAACACCAAGAAACCCCTGAATTTAAAGCAATTCAACAAAA
AGCTAATAAAGACCGCCCTCAGTTACAAGCTATGCTTGCTTATATACGTGAAGGTGATATAGTGGTTGTGACAGAATTAG
AACGCCTGGGTAGGAATAACAAGGAGCTAACTGAGGTCATGAATGATATTCAAGCCAAGGGGGCAACCTTGGAAGTCTTA
AATCTTCCCACTCTTCGAGGGATTGAGGATGACAACCTGAGACGGCTCTTGAACAATCTTATCCTGGAACTCTACAAGTA
CCAGGCACAAGCTGAAAGGGAACGCATAAAGGAACGGCAACGCCAAGGGATAGCTATTGCCAAGACTCAAGGAAAGTACA
AAGGCAGAAAAGCCATTTTTTCAGAAGATGACAGCAGGCTTCTTCATGCCTTTGACCTTTACCTTGAAGGTCTATCAGAT
AAAGACGTTGCCAAGCTAACAGGTATCAACGAACGTACTTTTAGGCGGTATCGTGAAAAGCATAAGATAAAAAGATAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10503.95 Da        Isoelectric Point: 4.3525

>AT196566 WP_095126119.1 NZ_CP071586:c956363-956073 [Pseudomonas germanica]
MTEEFTRFDAVEYLKTPEDMAAYLDACFDDDEGDGVLIRAALNDIARAQGMTQVARDAGLGRESLYKALSSTGNPEFATI
MKVMKALGLRLHAVTL

Download         Length: 291 bp

>AT196566 NZ_CP095162:c1210931-1210659 [Streptococcus suis]
ATGGCAGTTACGTATGAAAAAACATTTGAAATAGAGATCATTAACGAATTATCGGCAAGCGTTTATAATCGAGTATTAAA
CTATGTTTTGAACCATGAATTAAATAAAAATGACTCTCAATTATTGGAAGTCAATTTATTAAACCAATTAAAGCTTGCAA
AACGTGTAAATCTTTTTGATTATTCTTTAGAAGAATTACAAGCCGTTCATGAGTATTGGCGGTCAATGAATCGTTACTCA
AAACAAGTTTTGAATAAAGAGAAAGTGGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References