Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE(toxin)
Location 2726421..2726943 Replicon chromosome
Accession NZ_CP071503
Organism Shewanella sp. FJAT-51800

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag JYB87_RS12040 Protein ID WP_207353739.1
Coordinates 2726662..2726943 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JYB87_RS12035 Protein ID WP_207353738.1
Coordinates 2726421..2726672 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JYB87_RS12000 2721478..2722182 + 705 WP_207353731.1 helix-turn-helix domain-containing protein -
JYB87_RS12005 2722801..2723094 + 294 WP_207353732.1 hypothetical protein -
JYB87_RS12010 2723177..2723521 + 345 WP_207353733.1 hypothetical protein -
JYB87_RS12015 2723518..2724423 + 906 WP_207353734.1 PD-(D/E)XK nuclease-like domain-containing protein -
JYB87_RS12020 2724434..2725387 + 954 WP_207353735.1 recombinase RecT -
JYB87_RS12025 2725432..2726034 + 603 WP_207353736.1 phage N-6-adenine-methyltransferase -
JYB87_RS12030 2726027..2726251 + 225 WP_207353737.1 hypothetical protein -
JYB87_RS12035 2726421..2726672 + 252 WP_207353738.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
JYB87_RS12040 2726662..2726943 + 282 WP_207353739.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
JYB87_RS12045 2727111..2728145 + 1035 WP_207353740.1 hypothetical protein -
JYB87_RS12050 2728230..2729180 - 951 WP_207353741.1 TerC/Alx family metal homeostasis membrane protein -
JYB87_RS12055 2729540..2729734 - 195 WP_207353742.1 hypothetical protein -
JYB87_RS12060 2729831..2730472 - 642 WP_207353743.1 hypothetical protein -
JYB87_RS12065 2730513..2731139 - 627 WP_207353744.1 DUF2026 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2677053..2732504 55451


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10964.72 Da        Isoelectric Point: 10.3168

>T196494 WP_207353739.1 NZ_CP071503:2726662-2726943 [Shewanella sp. FJAT-51800]
MTYKLKFDKRALKEWEKLGYPVKTQFKKKLEERLENPRVPSAKLSGHADRYKIKLRSAGYRLVYQVFDEEIVVTVIAIGK
RENSDVYSLADNR

Download         Length: 282 bp

>T196494 NZ_CP095140:c2630735-2629413 [Klebsiella pneumoniae]
ATGGCGACGCTTACCACCTGGATGAACAATGTGCGCGTGGGAACCTTAACCCGCCAGGCTAACGGGGCGCACAGTTTTCG
CTATGAGGAAGAGTGGCTGCGCAGCCCGCGCGCCAGACCGCTCTCCCTCTCACTGCCGCTGCAGTATGGCAATATCACTG
CCGACGCGGTGTATCACTATTTTGATAACCTGCTGCCCGACAGCCCGCAGGTCCGCGACCGGATCGTCAGGCGCTATCAG
GCGCGCTCGAAGCAGCCGTTCGATCTGCTGGCCGAAGTCGGGCGGGATAGCGTAGGGGCGGTGACCCTCCTGCCGCCGGG
GGAAGAGGCGCACCTGGAAGGATTACGCTGGCAGACGCTGGACGAGGCGCAGCTCACCGCTTTGCTGACCGCTTACCAGT
CGGATATCCCCCTCGGGATGATTACCAGCCAGGACGATTTCCGTATCTCGGTGGCCGGCGCCCAGGAGAAAACGGCGCTG
CTGCGGATGGGCGAGCAGTGGTGTATTCCGCAGGGCGCCACGCCGACCACGCATATCATTAAGCTGCCCATCGGCGAGAT
CAAGCAGCCCAATGCGACGCTGGATCTGCGTGAAAGCGTGGATAATGAGTATCTGTGCCTGGCGCTGGCCAGAGAACTGG
GCCTGGCGGTGCCGGAAGCGGAGATCATCACCACCCCGCGGATCCGCGCCCTGGCGGTAACCCGCTTCGACCGGCGCTGG
GCGCAGGAGGGACGGGTGCTGCTGCGTCTGCCGCAGGAGGATCTGTGTCAGGCTTTTGGTCTTCCTTCAGCGATGAAATA
TGAGTCTGACGGCGGGCCGGGTATCGCCGCGATCATGACCTTTCTGCTGGGCTCGAGTGAAGCGCTGAAAGATCGCTATG
ACTTTATGAAGTTCATGGTCTTCCAGTGGCTGACGGGGGCGACGGACGGTCACGCAAAAAACTTCTCAATTTACCTGTTG
CCCGGCGGCAGCTACCGCTTAACACCGTTCTACGACATTATTTCGGCGTTTCCGGTGCTGGGCGGCACGGGACTGCATCT
GCGCGATCTGAAGCTGTCGATGGGGCTCAATGCCACAAAAGGGCGTAAAACAGAGATTAACGCCATCTATCCGCGTCATT
TTCTGGCGACGGCCAAAGCGGTGAACTTTCCCCGGGAGCAGATGCTGGCGATCCTCCAGGAGTTTGCCGGGCATGTGCCG
CAGGCAATCGAAAGCGCTCGCCGGACGCTGCCGGCGGACTTTTCCAGCCACGTCTGGCAGGCCATTACAGAGAACATGCT
GAAGCTGCACGCCCGCCTGCAGCAAGGGCTGCAGGCGCTATAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9243.44 Da        Isoelectric Point: 3.7804

>AT196494 WP_207353738.1 NZ_CP071503:2726421-2726672 [Shewanella sp. FJAT-51800]
MAYQILTSVAASITELKKNPMGTALEGEGQPVAILNRNEPAFYIVPPALFGYFQELAEDAELNRIADERMQEPDFVEVNI
DDL

Download         Length: 252 bp

>AT196494 NZ_CP095140:c2631001-2630735 [Klebsiella pneumoniae]
ATGAATTCCCCGCAGATATACAGTCCCGTGCAGCTGGCCAATTACATGAAGCTGCTGCGCCAGCAGAACCACTGGACCCA
GGATGCGCTGGCCAGGCGGATCGGCATTAAGCAGGCCACGCTGTCCAATTTTGAAAATCACCCCGACAAAACCACCTTAA
CCACGCTGTTTAAGATCCTCCAGTCGCTGGGGGTGGTGATGACGCTGAACGCCAAAGCTGCTGAGACGGCGCCGGCTCCC
GATAACAACACGGACCTTGACTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References