Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /GNAT-DUF1778
Location 1072448..1073214 Replicon chromosome
Accession NZ_CP071503
Organism Shewanella sp. FJAT-51800

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag JYB87_RS04645 Protein ID WP_207355743.1
Coordinates 1072720..1073214 (+) Length 165 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag JYB87_RS04640 Protein ID WP_207355742.1
Coordinates 1072448..1072723 (+) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JYB87_RS04615 1069282..1070076 - 795 WP_207355738.1 class I SAM-dependent methyltransferase -
JYB87_RS04620 1070309..1070782 - 474 WP_207355739.1 DNA starvation/stationary phase protection protein -
JYB87_RS04625 1070958..1071305 + 348 WP_207355740.1 DNA polymerase III subunit psi -
JYB87_RS04630 1071302..1071760 + 459 WP_207356591.1 ribosomal protein S18-alanine N-acetyltransferase -
JYB87_RS04635 1071791..1072117 - 327 WP_207355741.1 YceK/YidQ family lipoprotein -
JYB87_RS04640 1072448..1072723 + 276 WP_207355742.1 DUF1778 domain-containing protein Antitoxin
JYB87_RS04645 1072720..1073214 + 495 WP_207355743.1 GNAT family N-acetyltransferase Toxin
JYB87_RS04650 1073597..1073923 - 327 WP_207355744.1 hypothetical protein -
JYB87_RS04655 1074570..1075535 - 966 WP_207355745.1 lipoyl synthase -
JYB87_RS04660 1075532..1076188 - 657 WP_207355746.1 lipoyl(octanoyl) transferase LipB -
JYB87_RS04665 1076276..1076542 - 267 WP_037443561.1 DUF493 family protein YbeD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(85-154)

Antitoxin

Vibrio phage ICP1, Orf50

(7-85)


Sequences

Toxin        


Download         Length: 165 a.a.        Molecular weight: 18278.91 Da        Isoelectric Point: 7.2426

>T196493 WP_207355743.1 NZ_CP071503:1072720-1073214 [Shewanella sp. FJAT-51800]
MNTVLLDKDKHDRNRFNCGIDALNNYFKVMASQQAKKDNTRTFVLEDDTDNSAVIGFYTLTMTPIDLNALPIKLQKKHPS
SMSGGLIARLAVDNRYQGRGFGEWLLIDALRKLLAASDTVAFPIVIVDAKDGAAHFCEKYGFTAFQDTENKLFITIADIR
ASLS

Download         Length: 495 bp

>T196493 NZ_CP095140:1931998-1932100 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 9846.37 Da        Isoelectric Point: 9.7672

>AT196493 WP_207355742.1 NZ_CP071503:1072448-1072723 [Shewanella sp. FJAT-51800]
MASTLPRITARVDLDTQDLLTKAAAIAGMSSINSFVLNAAIEKAKQVIEREETLKLSRIDAMALMDALDQPAKANTKLQA
AAKRYDGKSQQ

Download         Length: 276 bp

>AT196493 NZ_CP095140:c1932107-1931962 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References