Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2048806..2048951 Replicon chromosome
Accession NZ_CP071464
Organism Klebsiella pneumoniae strain C2244

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2048842..2048944 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2048806..2048951 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J1C69_RS10020 2043936..2045996 + 2061 WP_004151449.1 oligopeptidase B -
J1C69_RS10025 2046000..2046659 - 660 WP_002911407.1 exodeoxyribonuclease X -
J1C69_RS10030 2046738..2046968 - 231 WP_002911406.1 DNA polymerase III subunit theta -
J1C69_RS10035 2047081..2047455 + 375 WP_004151448.1 CopC domain-containing protein YobA -
J1C69_RS10040 2047459..2048328 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
J1C69_RS10045 2048345..2048683 + 339 WP_002911404.1 YebY family protein -
- 2048806..2048951 - 146 - - Antitoxin
- 2048842..2048944 + 103 - - Toxin
J1C69_RS10050 2049319..2049462 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
J1C69_RS10055 2049567..2050535 - 969 WP_004151446.1 VirK/YbjX family protein -
J1C69_RS10060 2050692..2051345 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
J1C69_RS10065 2051342..2051533 - 192 WP_002911395.1 YebW family protein -
J1C69_RS10070 2051631..2051870 - 240 WP_002911393.1 YebV family protein -
J1C69_RS10075 2051986..2053419 - 1434 WP_101345779.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T196446 NZ_CP071464:2048842-2048944 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT196446 NZ_CP071464:c2048951-2048806 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References