Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 229853..230544 Replicon plasmid p2
Accession NZ_CP071456
Organism Rhizobium lentis strain BLR27

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag J0663_RS27440 Protein ID WP_207245535.1
Coordinates 230104..230544 (+) Length 147 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag J0663_RS27435 Protein ID WP_207245534.1
Coordinates 229853..230107 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J0663_RS27420 227446..228303 - 858 WP_207245532.1 SDR family oxidoreductase -
J0663_RS27425 228413..228649 + 237 WP_207245925.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
J0663_RS27430 228928..229767 + 840 WP_207245533.1 helix-turn-helix domain-containing protein -
J0663_RS27435 229853..230107 + 255 WP_207245534.1 plasmid stabilization protein Antitoxin
J0663_RS27440 230104..230544 + 441 WP_207245535.1 PIN domain-containing protein Toxin
J0663_RS27445 230569..231777 - 1209 WP_207245536.1 amidohydrolase/deacetylase family metallohydrolase -
J0663_RS27450 232033..232902 - 870 WP_207245537.1 sigma-70 family RNA polymerase sigma factor -
J0663_RS27455 233010..233468 + 459 WP_207245538.1 carboxymuconolactone decarboxylase family protein -
J0663_RS27460 233533..234825 - 1293 WP_207245539.1 L-rhamnose catabolism isomerase -
J0663_RS27465 234905..235063 + 159 WP_064697274.1 YqaE/Pmp3 family membrane protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..422827 422827


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-119)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 147 a.a.        Molecular weight: 15556.78 Da        Isoelectric Point: 6.4716

>T196438 WP_207245535.1 NZ_CP071456:230104-230544 [Rhizobium lentis]
MIVLDTNVLSETMKPTPSSAVRAWLNEQAAETLYLSSVTLAELMFGIGADGRRKAALTEMLGGLLALFGDRVLPFDAGAA
RHYADLAVRARMNGKGFPTPDGYIAAIAASKGFTVATRDMGPFEAAGLTVVNPWNHRSSEASRENL

Download         Length: 441 bp

>T196438 NZ_CP095125:c2398851-2398675 [Escherichia coli]
GTGAAACAAAGCGAGTTCAGACGTTGGCTCGAATCTCAGGGCGTCGATGTAGCGAATAGCAGCAACCATTTGAAACTCAG
GTTTCATGGGAGGCGCAGTGTCATGCCGCGTCACCCCTGCGATGAGATTAAAGAACCATTGCGTAAAGCAATCCTGAAAC
AACTCGGTTTGAGTTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9512.86 Da        Isoelectric Point: 5.1891

>AT196438 WP_207245534.1 NZ_CP071456:229853-230107 [Rhizobium lentis]
MAVLTVRNVPDEVHRALRVRAAMHGRSTEAEVREILESAVKPEQRIRMGDALAELGRQLGLTNDDLEVLDQLRERAPAEP
LRFE

Download         Length: 255 bp

>AT196438 NZ_CP095125:c2398629-2398213 [Escherichia coli]
ATGCGTTATCCCGTCACTCTTACACCCGCGCCGGAAGGCGGTTATATGGTTTCTTTTGTGGATATCCCTGAAGCGTTGAC
CCAGGGCGAAACTGTCGCTGAAGCGATGGAAGCGGCAAAAGATGCTTTACTGACCGCATTTGATTTTTATTTTGAAGATA
ACGAGCTTATCCCTTTACCTTCGCCATTAAATAGTCACGATCACTTTATTGAAGTACCTTTGAGCGTCGCCTCTAAGGTA
TTGCTGTTAAATGCTTTTTTACAGTCAGAAATCACTCAGCAAGAGTTAGCCAGGCGAATTGGCAAACCTAAACAGGAGAT
TACTCGCCTATTTAACTTGCATCATGCGACAAAAATCGACGCCGTCCAGCTCGCGGCAAAGGCGCTTGGCAAAGAGTTAT
CGCTGGTGATGGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References