Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 550883..551481 Replicon plasmid p1
Accession NZ_CP071455
Organism Rhizobium lentis strain BLR27

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag J0663_RS24735 Protein ID WP_207244663.1
Coordinates 550883..551176 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag J0663_RS24740 Protein ID WP_183704861.1
Coordinates 551173..551481 (-) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J0663_RS24710 546552..547517 - 966 WP_207244662.1 DUF1349 domain-containing protein -
J0663_RS24715 547752..548162 + 411 WP_096772345.1 transposase -
J0663_RS24720 548159..548506 + 348 WP_095436757.1 IS66 family insertion sequence element accessory protein TnpB -
J0663_RS24725 548552..550207 + 1656 WP_207243129.1 IS66 family transposase -
J0663_RS24730 550216..550491 + 276 WP_207243130.1 hypothetical protein -
J0663_RS24735 550883..551176 - 294 WP_207244663.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
J0663_RS24740 551173..551481 - 309 WP_183704861.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
J0663_RS24745 551778..552424 + 647 Protein_524 IS21-like element helper ATPase IstB -
J0663_RS24750 552489..552665 - 177 WP_207245512.1 hypothetical protein -
J0663_RS24755 552992..553732 + 741 WP_183704862.1 SDR family oxidoreductase -
J0663_RS24760 554012..554248 - 237 WP_207244664.1 hypothetical protein -
J0663_RS24765 554375..555889 - 1515 WP_207245492.1 GMC family oxidoreductase N-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB 1..877212 877212
- inside IScluster/Tn - - 547752..552424 4672


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-51)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10562.07 Da        Isoelectric Point: 5.7996

>T196436 WP_207244663.1 NZ_CP071455:c551176-550883 [Rhizobium lentis]
VKLTWSAFALSDRDAIFTYIEAENPSAAVMIDERIMAAARRLVDFPASGRVGRIAGTRELVINGTPYIAAYVATETAVRV
LRVLHGSQEWPDTLPGS

Download         Length: 294 bp

>T196436 NZ_CP095125:1998957-1999060 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11179.60 Da        Isoelectric Point: 4.8892

>AT196436 WP_183704861.1 NZ_CP071455:c551481-551173 [Rhizobium lentis]
MAANALVQTRIDAEVRDRASAVLENMGLTVSDAVRILLTRTANEGALPLELFSGSEAHDAWFRTKVLEALNDTRPDVSDF
DVEAHFEERRAIARVKAGALKS

Download         Length: 309 bp

>AT196436 NZ_CP095125:c1999098-1998827 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References