Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 2904877..2905505 Replicon chromosome
Accession NZ_CP071409
Organism [Pantoea] beijingensis strain JZB2120001

Toxin (Protein)


Gene name Hha Uniprot ID -
Locus tag J1C60_RS13205 Protein ID WP_128179335.1
Coordinates 2905287..2905505 (+) Length 73 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID -
Locus tag J1C60_RS13200 Protein ID WP_128179336.1
Coordinates 2904877..2905257 (+) Length 127 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J1C60_RS13170 2900691..2900945 + 255 WP_128179341.1 type B 50S ribosomal protein L31 -
J1C60_RS13175 2900958..2901098 + 141 WP_128179340.1 type B 50S ribosomal protein L36 -
J1C60_RS13180 2901145..2902023 - 879 WP_128179339.1 metal ABC transporter substrate-binding protein -
J1C60_RS13185 2902020..2902889 - 870 WP_128179440.1 metal ABC transporter permease -
J1C60_RS13190 2902892..2903578 - 687 WP_128179338.1 ATP-binding cassette domain-containing protein -
J1C60_RS13195 2904122..2904475 + 354 WP_128179337.1 hypothetical protein -
J1C60_RS13200 2904877..2905257 + 381 WP_128179336.1 Hha toxicity modulator TomB Antitoxin
J1C60_RS13205 2905287..2905505 + 219 WP_128179335.1 HHA domain-containing protein Toxin
J1C60_RS13215 2906331..2906642 + 312 WP_128179334.1 MGMT family protein -
J1C60_RS13220 2906742..2907299 - 558 WP_128179333.1 YbaY family lipoprotein -
J1C60_RS13225 2907472..2908404 - 933 WP_128179332.1 LysR family transcriptional regulator -
J1C60_RS13230 2908515..2909717 + 1203 WP_128179331.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(13-69)

Antitoxin

Biofilm formation regulator YbaJ

(1-114)


Sequences

Toxin        


Download         Length: 73 a.a.        Molecular weight: 8655.97 Da        Isoelectric Point: 7.9893

>T196332 WP_128179335.1 NZ_CP071409:2905287-2905505 [[Pantoea] beijingensis]
MTDKTLTKTDYLMRLRRCRSIDTLERVIEKNKYELSDDELEVFNSAADHRLAELTMNKLYDKVPVSVWKYVR

Download         Length: 219 bp

>T196332 NZ_CP095088:1032217-1032552 [Escherichia coli]
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCTGG
ACATCGTCCAGCTGTTGTCCTGAGTCCTTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTGTACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACAGTTGCCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTACTGATTGGGTAG

Antitoxin


Download         Length: 127 a.a.        Molecular weight: 14656.42 Da        Isoelectric Point: 4.4796

>AT196332 WP_128179336.1 NZ_CP071409:2904877-2905257 [[Pantoea] beijingensis]
MDEYSPKRHDIAQLKFLCENLYDESMTTLGDSHHGWVNDPTSAINLQLNELIEHIASFTMNYKIKHVEDSDLIGQIDEYL
DDTFMLFSNYGINAQDLNRWQKSAKRLFNIFAEECALLPLQPSHSF

Download         Length: 381 bp

>AT196332 NZ_CP095088:1031969-1032217 [Escherichia coli]
ATGATCCACAGTAGCGTAAAGCGTTGGGGAAATTCACCGGCGGTGCGGATCCCGGCTACGTTAATGCAGGCGCTCAATCT
GAATATTGATGATGAAGTGAAGATTGACCTGGTGGATGGCAAATTAATTATTGAGCCAGTGCGTAAAGAGCCCGTATTTA
CGCTTGCTGAACTGGTCAACGACATCACGCCGGAAAACCTCCACGAGAATATCGACTGGGGAGAGCCGAAAGATAAGGAA
GTCTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References