196320

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 2967487..2968104 Replicon chromosome
Accession NZ_CP071405
Organism Pantoea deleyi strain LMG24200

Toxin (Protein)


Gene name Hha Uniprot ID -
Locus tag J1C59_RS14075 Protein ID WP_128084885.1
Coordinates 2967889..2968104 (+) Length 72 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID -
Locus tag J1C59_RS14070 Protein ID WP_128084884.1
Coordinates 2967487..2967864 (+) Length 126 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J1C59_RS14040 2963798..2964052 + 255 WP_111140303.1 type B 50S ribosomal protein L31 -
J1C59_RS14045 2964063..2964197 + 135 Protein_2732 type B 50S ribosomal protein L36 -
J1C59_RS14050 2964250..2965128 - 879 WP_140917130.1 metal ABC transporter substrate-binding protein -
J1C59_RS14055 2965144..2965983 - 840 WP_140917129.1 metal ABC transporter permease -
J1C59_RS14060 2965980..2966648 - 669 WP_140917128.1 ATP-binding cassette domain-containing protein -
J1C59_RS14065 2966986..2967339 + 354 WP_128084883.1 hypothetical protein -
J1C59_RS14070 2967487..2967864 + 378 WP_128084884.1 Hha toxicity modulator TomB Antitoxin
J1C59_RS14075 2967889..2968104 + 216 WP_128084885.1 HHA domain-containing protein Toxin
J1C59_RS14085 2968509..2968820 + 312 WP_128084886.1 MGMT family protein -
J1C59_RS14090 2968858..2969415 - 558 WP_128084887.1 YbaY family lipoprotein -
J1C59_RS14095 2969606..2970469 + 864 WP_128084888.1 acyl-CoA thioesterase II -
J1C59_RS14100 2970519..2971805 - 1287 WP_128084889.1 ammonium transporter AmtB -
J1C59_RS14105 2971840..2972178 - 339 WP_003850469.1 P-II family nitrogen regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(12-68)

Antitoxin

Biofilm formation regulator YbaJ

(1-114)


Sequences

Toxin        


Download         Length: 72 a.a.        Molecular weight: 8480.92 Da        Isoelectric Point: 9.8189

>T196320 WP_128084885.1 NZ_CP071405:2967889-2968104 [Pantoea deleyi]
MNKTLTKTDYLMRLRRCRSLDTLERVIEKNKYELPEAELAIFYSAADHRLAELTMNKLYDKVPGSVWKFVR

Download         Length: 216 bp

>T196320 NZ_CP095086:4671420-4671797 [Escherichia coli]
ATGAATACATTACCCGACACTCACGTACGGGAGGCATCGGGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCGACTGCTGGACCAGCACTATGGCCTCACGCTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGGATTTCACTGTGTGACGCGGTGAACTTTCTCGTTGAAAAATACGCGCTGGTACGTACCGACCAGCCGGGATTC
AGCGCAGGAGCCCCGTCGCAGTTAATCAACAGCATTGATATTCTCCGGGCTCGCAGGGCAACCGGCCTGATGACCCGGAA
CAATTACAGAATGGTAAATAACATTACCCAGGGCAAGCATCCGGAGGCAAAACAATGA

Antitoxin


Download         Length: 126 a.a.        Molecular weight: 14609.23 Da        Isoelectric Point: 4.3976

>AT196320 WP_128084884.1 NZ_CP071405:2967487-2967864 [Pantoea deleyi]
MDEYSPKRHDIAQLKYLCESLFDDSMASLTDSHHGWVNDPTSESNLQLNDLIEHIASFTMNYKIKHVEDEALISQIDEYL
DDTFMLFSNYGVTSPDLQRWQRSAKRLFNLFTEECAFLQQPSHSL

Download         Length: 378 bp

>AT196320 NZ_CP095086:4670996-4671373 [Escherichia coli]
GTGTCAGACACACTGCCCGGGACAACGCATCCCGACGACAATCACGACCGCCCCTGGTGGGGGCTGCCCTGCACCGTGAC
GCCCTGTTTCGGGGCACGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCCGACCGTGCCGGTATCAGAGGCCGGT
TCAGCGACGCGGATGCATACCACCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCATCACACTGTATGCGAAAGGGCTGACCTGCGAAGCCGATACCCTTGGCAGTTG
TGGTTACGTTTATCTGGCTGTTTATCCGACACCGGCAGCGCCCGCAATCACCGTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References