Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 3446042..3446760 Replicon chromosome
Accession NZ_CP071399
Organism Rhizobium leguminosarum strain OyaliB

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag J0664_RS17175 Protein ID WP_207156355.1
Coordinates 3446302..3446760 (+) Length 153 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag J0664_RS17170 Protein ID WP_207156354.1
Coordinates 3446042..3446305 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J0664_RS17155 3441548..3441985 + 438 WP_041936180.1 nucleoside deaminase -
J0664_RS17160 3442035..3442664 - 630 WP_028743735.1 hypothetical protein -
J0664_RS17165 3442798..3445689 - 2892 WP_207156353.1 isoleucine--tRNA ligase -
J0664_RS17170 3446042..3446305 + 264 WP_207156354.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
J0664_RS17175 3446302..3446760 + 459 WP_207156355.1 PIN domain-containing protein Toxin
J0664_RS17180 3446972..3447382 + 411 WP_077976703.1 DUF2384 domain-containing protein -
J0664_RS17185 3447509..3447943 + 435 WP_207156356.1 RES domain-containing protein -
J0664_RS17190 3447932..3448924 - 993 WP_207158798.1 bifunctional riboflavin kinase/FAD synthetase -
J0664_RS17195 3448956..3449804 - 849 WP_094086648.1 TIGR01459 family HAD-type hydrolase -
J0664_RS17200 3450200..3450496 + 297 WP_003545797.1 co-chaperone GroES -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-125)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(7-55)


Sequences

Toxin        


Download         Length: 153 a.a.        Molecular weight: 16923.15 Da        Isoelectric Point: 7.3174

>T196310 WP_207156355.1 NZ_CP071399:3446302-3446760 [Rhizobium leguminosarum]
VIGWLLDTNVIAALINPNGALSVKSWAAAQDEKKMFVSILTLAEYDKGIENLPEDDQNRYRYAASRDALEERFSQRVLSL
SDAAVRHWGVISGRVKLKTGHAPSVVDTLLAATAIEHNLYLVTRNVRDTRFSGAAIFDPWTNDPGQFPLSRR

Download         Length: 459 bp

>T196310 NZ_CP095086:2540343-2541665 [Escherichia coli]
ATGCCTAAACTAGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCCAACGGCGCGCACACCTTTAA
GTATGCACCTGAGTGGTTAGCCAGCCGTTATGCCAGACCGTTGTCACTTTCGCTGCCATTGCAGAGGAGGAATATCACCT
CTGATGCCGTATTTAACTTCTTCGATAACCTGTTACCCGATAGCCCGATTGTACGTGACCGGATCGTTAAACGTTATCAT
GCTAAATCCAGACAACCGTTTGATTTATTGTCAGAAATAGGGCGAGACAGCGTTGGTGCCGTGACGTTAATCCCCGAAGA
TGAAACCGTAATGTGTCCGATAATGGCATGGGAAAAGCTTACTGAAGCCAGACTTGAAGAAGTATTAACGGCTTATAAAG
CAGATATCCCGTTAGGCATGATTAGAGAAGAAAATGACTTTCGCATCTCGGTTGCTGGCGCACAGGAGAAGACTGCGCTG
CTCAGAATAGGCAATGACTGGTGCATTCCGAAGGGAATAACGCCAACGACGCACATTATCAAATTGCCGATTGGCGAAAT
CAGACAGCCCAATGCGACGCTCGATCTTAGCCAAAGCGTTGATAATGAGTATTACTGTTTGCTGCTGGCGAAAGAACTCG
GGTTGAATGTTCCGGACGCAGAAATCATTAAAGCGGGAAGGGTGCGCGCGTTAGCGGTCAAACGTTTTGACAGGCGTTGG
AATACTGAGCGAACGGTTTTACTTCGCTTGCCACAGGAGGATATGTGCCAGACATTCGGTTTACCTTCATCGGTGAAATA
TGAATCAGATGGAGGCCCCGGTATCGCGCAAATTATGGCTTTTTTGATGGGGTCCAGCGAGGCGCTGAAAGATCGCTATG
ATTTTATGAAGTTTCAGGTCTTCCAGTGGTTGATTGGCGCAACAGATGGCCATGCAAAAAACTTCTCCGTATTTATTCAG
GCTGGCGGCAGTTATCGGCTCACACCATTTTATGACATCATTTCGGCATTTCCGGTCCTTGGCGGTACGGGAATACACAT
CAGCGATCTCAAACTGGCAATGGGGCTTAACGCATCCAAAGGCAAAAAAACGGCAATCGATAAAATTTATCCGCGACATT
TTCTGGCGACAGCAAAGGTGCTGAAATTCCCGGAAGTGCAGATGCATGAAATCCTGAGTGACTTTGCCAGAATGATTCCG
GCAGCACTGGATAACGTGAAGACTTCATTACCGACAGATTTTCCGGAGAACGTGGTGACGGCAGTTGAAACCAATGTGTT
GAGGTTGCACGGTCGGTTAAGCCGAGAATACGGTATTAAGTAA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9987.43 Da        Isoelectric Point: 8.5833

>AT196310 WP_207156354.1 NZ_CP071399:3446042-3446305 [Rhizobium leguminosarum]
MKKITKQSWKLEDAKARFSEVVRRAHSEGPQRVTVRGRDSVVVISAEELDRLTKVEPKKPFVAFMESLDLKGLDLEREAD
YGRDAEL

Download         Length: 264 bp

>AT196310 NZ_CP095086:2540077-2540343 [Escherichia coli]
ATGATGAGCTTTCAGAAGATCTATAGCCCAATGCAATTGGCGAATGCAATGAAACTGGTTCGCCAGCAAAACGGCTGGAC
GCAGAGCGAGTTGGCGAAAAAAATCGGCATTAAGCAGGCGACAATTTCCAATTTCGAAAACAATCCTAACAATACCTCGC
TCACGACATTTTTTAAGATTTTACAGTCGCTTGAACTCTCAATGACGCTATGCGACGCAAAAAATGCCTCGCCAGAAGCA
ACAGAACAGCAAGATCTGGAGTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References