Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1906977..1907122 Replicon chromosome
Accession NZ_CP071385
Organism Klebsiella pneumoniae strain wxc2020

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1907013..1907115 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1906977..1907122 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J1F26_RS09250 1902107..1904167 + 2061 WP_004151449.1 oligopeptidase B -
J1F26_RS09255 1904171..1904830 - 660 WP_002911407.1 exodeoxyribonuclease X -
J1F26_RS09260 1904909..1905139 - 231 WP_002911406.1 DNA polymerase III subunit theta -
J1F26_RS09265 1905252..1905626 + 375 WP_004151448.1 CopC domain-containing protein YobA -
J1F26_RS09270 1905630..1906499 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
J1F26_RS09275 1906516..1906854 + 339 WP_004189269.1 YebY family protein -
- 1906977..1907122 - 146 - - Antitoxin
- 1907013..1907115 + 103 - - Toxin
J1F26_RS09280 1907489..1907632 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
J1F26_RS09285 1907737..1908705 - 969 WP_004151446.1 VirK/YbjX family protein -
J1F26_RS09290 1908862..1909515 + 654 WP_004189273.1 protein-serine/threonine phosphatase -
J1F26_RS09295 1909512..1909703 - 192 WP_002911395.1 YebW family protein -
J1F26_RS09300 1909801..1910040 - 240 WP_002911393.1 YebV family protein -
J1F26_RS09305 1910156..1911589 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T196269 NZ_CP071385:1907013-1907115 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT196269 NZ_CP071385:c1907122-1906977 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References