Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1205878..1206534 Replicon chromosome
Accession NZ_CP071320
Organism Serratia ureilytica strain T6

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag J0X03_RS05585 Protein ID WP_108681740.1
Coordinates 1206145..1206534 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag J0X03_RS05580 Protein ID WP_019452401.1
Coordinates 1205878..1206141 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J0X03_RS05555 1200916..1202130 - 1215 WP_122016724.1 D-galactonate dehydratase family protein -
J0X03_RS05560 1202299..1203204 - 906 WP_033644066.1 lipid kinase YegS -
J0X03_RS05565 1203234..1203455 + 222 WP_139120358.1 hypothetical protein -
J0X03_RS05570 1203672..1205024 - 1353 WP_046687633.1 tRNA 5-hydroxyuridine modification protein YegQ -
J0X03_RS05575 1205203..1205541 - 339 WP_033644064.1 YegP family protein -
J0X03_RS05580 1205878..1206141 + 264 WP_019452401.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
J0X03_RS05585 1206145..1206534 + 390 WP_108681740.1 type II toxin-antitoxin system VapC family toxin Toxin
J0X03_RS05590 1206542..1207258 - 717 WP_129993536.1 two-component system response regulator BaeR -
J0X03_RS05595 1207258..1208640 - 1383 WP_033644061.1 two-component system sensor histidine kinase BaeS -
J0X03_RS05600 1208637..1210067 - 1431 WP_033644060.1 multidrug transporter subunit MdtD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-119)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 14355.61 Da        Isoelectric Point: 7.8794

>T196180 WP_108681740.1 NZ_CP071320:1206145-1206534 [Serratia ureilytica]
MYMFDTNTVSHLFRQHPQVLNVMEKLPPSAVCISSVTEAELLYGVAKRRNKALQSMVEAFLAAVTVYAWDSEAARCYGEM
RANMERKGKIMGAMDQLIAAHAQSRGATLVTNDRAFAMVPGLAVEDWTR

Download         Length: 390 bp

>T196180 NZ_CP071320:1206145-1206534 [Serratia ureilytica]
ATGTACATGTTTGATACCAACACCGTCAGCCACTTGTTTCGGCAGCATCCGCAGGTGCTTAACGTCATGGAAAAGCTCCC
GCCTTCTGCCGTATGTATTTCCAGCGTCACGGAGGCGGAACTGCTTTACGGTGTGGCTAAACGGCGGAACAAGGCGTTGC
AAAGCATGGTCGAGGCCTTTCTTGCCGCGGTGACGGTCTATGCATGGGATAGCGAGGCTGCCCGCTGTTACGGTGAAATG
CGGGCAAACATGGAGAGAAAGGGCAAAATCATGGGCGCGATGGATCAACTGATCGCCGCTCATGCGCAGAGCCGTGGCGC
GACGCTGGTGACCAACGATCGCGCATTCGCCATGGTGCCCGGATTGGCGGTTGAGGACTGGACGCGCTGA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 10048.29 Da        Isoelectric Point: 4.6583

>AT196180 WP_019452401.1 NZ_CP071320:1205878-1206141 [Serratia ureilytica]
MERIAKLFKNGRNQAVRLPVEFEFDTDRVYIRRDREGNVILSKYPAKPDSWAPLLSIIAQTPVPQEFLGAEDRQQGVADR
DPFSEDE

Download         Length: 264 bp

>AT196180 NZ_CP071320:1205878-1206141 [Serratia ureilytica]
ATGGAAAGAATCGCAAAGCTGTTTAAAAACGGCAGAAATCAGGCGGTGAGGTTACCGGTGGAATTTGAATTTGATACGGA
TCGTGTCTATATCCGTCGCGATAGGGAGGGCAACGTGATTTTATCCAAATATCCAGCAAAGCCGGACAGCTGGGCACCGC
TGCTGAGCATTATCGCCCAAACGCCGGTGCCGCAAGAGTTTCTTGGCGCGGAAGATCGTCAGCAAGGGGTTGCAGACCGC
GATCCATTCTCAGAGGACGAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References