Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 298042..298634 Replicon chromosome
Accession NZ_CP071320
Organism Serratia ureilytica strain T6

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag J0X03_RS01340 Protein ID WP_089197523.1
Coordinates 298042..298392 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag J0X03_RS01345 Protein ID WP_089197522.1
Coordinates 298386..298634 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J0X03_RS01325 293601..293927 - 327 WP_038878129.1 nitrite reductase small subunit NirD -
J0X03_RS01330 293924..296473 - 2550 WP_103101818.1 nitrite reductase large subunit NirB -
J0X03_RS01335 296762..298045 + 1284 WP_160204668.1 cytosine deaminase -
J0X03_RS01340 298042..298392 - 351 WP_089197523.1 type II toxin-antitoxin system ChpB family toxin Toxin
J0X03_RS01345 298386..298634 - 249 WP_089197522.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
J0X03_RS01350 298745..299929 - 1185 WP_033636290.1 MFS transporter TsgA -
J0X03_RS01355 300121..301101 - 981 WP_033645266.1 LacI family transcriptional regulator -
J0X03_RS01360 301174..302481 - 1308 WP_046687917.1 6-phospho-beta-glucosidase -
J0X03_RS01365 302478..302816 - 339 WP_025304525.1 PTS lactose/cellobiose transporter subunit IIA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-114)

Antitoxin

SpoVT-AbrB domain

(6-49)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12390.38 Da        Isoelectric Point: 11.5657

>T196176 WP_089197523.1 NZ_CP071320:c298392-298042 [Serratia ureilytica]
MVKRPVFQRGDLIRVSLNPVVGREQQGDFRPALVLSPREFNALGMVLVAPISQGANFARTAGFTVSLSGSGTATQGVILI
NQVRMMDLAGRSAQFVERAPGEVIADALARLQAIID

Download         Length: 351 bp

>T196176 NZ_CP095022:c1576003-1575602 [Mycobacterium tuberculosis]
ATGATCCTTGTCGACTCCGATGTGCTGATCGCGCATTTGCGGGGTGTCGTTGCTGCTCGCGATTGGCTTGTCAGCGCCCG
CAAGGACGGACCGCTGGCGATCAGCGTGGTGTCCACCGCCGAACTCATCGGCGGAATGCGGACCGCCGAACGGCGCGAGG
TGTGGCGCCTGCTTGCATCGTTTCGGGTACAGCCAGCAACCGAGGTAATCGCACGCCGCGCCGGCGACATGATGCGCCGA
TATCGTCGCAGCCACAACCGGATTGGACTTGGCGACTATCTGATAGCTGCTACCGCCGACGTCCAGGACCTGCAATTGGC
AACCCTCAACGTGTGGCATTTCCCCATGTTCGAGCAGCTGAAACCACCATTTGCGGTGCCGGGGCACCGACCGCGGGCAT
GA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9129.58 Da        Isoelectric Point: 4.5026

>AT196176 WP_089197522.1 NZ_CP071320:c298634-298386 [Serratia ureilytica]
MKVFIKKWGNSAGMLVPSALMNELELQVGQEMDMQVIDGTLVIKPVKKRYSLQQLLDSCDGEAPAAADDNWEHMPPAGKE
VW

Download         Length: 249 bp

>AT196176 NZ_CP095022:c1576257-1576000 [Mycobacterium tuberculosis]
ATGAAGCGGACCAACATCTACCTCGACGAGGAGCAGACGGCAAGCCTCGACAAGTTGGCCGCGCAAGAAGGTGTTTCGCG
CGCCGAGCTGATCCGCCTCCTGCTGAACCGAGCCCTCACCACCGCTGGGGACGACCTTGCATCGGACCTGCAGGCTATAA
ACGATTCGTTCGGCACGCTTCGCCACCTGGATCCGCCGGTGCGTCGCTCCGGTGGTCGTGAACAGCACCTTGCCCAGGTG
TGGCGCGCCACCTCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References