Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1210026..1210693 Replicon chromosome
Accession NZ_CP071312
Organism Rhizobium sp. X9

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JZY08_RS20480 Protein ID WP_112585197.1
Coordinates 1210283..1210693 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JZY08_RS20475 Protein ID WP_112585195.1
Coordinates 1210026..1210286 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JZY08_RS20460 1205726..1207513 + 1788 WP_112585936.1 DUF3363 domain-containing protein -
JZY08_RS20465 1207529..1209529 + 2001 WP_112585191.1 conjugal transfer protein TraG -
JZY08_RS20470 1209539..1209964 + 426 WP_112585193.1 ribbon-helix-helix protein, CopG family -
JZY08_RS20475 1210026..1210286 + 261 WP_112585195.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
JZY08_RS20480 1210283..1210693 + 411 WP_112585197.1 type II toxin-antitoxin system VapC family toxin Toxin
JZY08_RS20485 1210740..1211138 - 399 WP_216331575.1 hypothetical protein -
JZY08_RS20490 1211135..1211785 - 651 WP_112585201.1 glutathione S-transferase family protein -
JZY08_RS20495 1212141..1213139 + 999 WP_009452107.1 P-type conjugative transfer ATPase TrbB -
JZY08_RS20500 1213136..1213465 + 330 WP_009452106.1 TrbC/VirB2 family protein -
JZY08_RS20505 1213465..1213746 + 282 WP_097136820.1 VirB3 family type IV secretion system protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1171274..1217049 45775


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-126)

Antitoxin

SpoVT-AbrB domain

(8-48)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15165.21 Da        Isoelectric Point: 7.0182

>T196169 WP_112585197.1 NZ_CP071312:1210283-1210693 [Rhizobium sp. X9]
VTFRLLDTNAVISLVARRSEPLLQRVETSEPGSLAVSSVVAHELYFGAYRSERVAYNLETLRLLFTDLAILDFDREDARV
AGEIRAELKRRGTPIGPYDTLIAGQAKARGLTLVTNNTGEFSRIAGLRIEDWTTNR

Download         Length: 411 bp

>T196169 NZ_CP095022:840096-840524 [Mycobacterium tuberculosis]
ATGTTCCTTCTCGACGCCAACGTGCTGCTGGCTGCACACCGCGGTGACCACCCGAATCACCGAACCGTCCGCCCCTGGTT
CGATCGACTGCTCGCGGCTGACGACCCCTTCACAGTGCCGAACCTGGTATGGGCGTCGTTCCTCCGGCTGGCAACGAATC
GACGCATCTTCGAGATTCCGTCACCGCGAGCAGAGGCATTCGCATTCGTCGAAGCCGTCACCGCCCAGCCCCATCACCTT
CCGACGAACCCCGGTCCCAGACACCTCATGCTGCTGCGAAAACTCTGCGACGAGGCCGACGCATCGGGCGACTTGATACC
TGACGCGGTACTCGCGGCCATAGCAGTGGGGCATCACTGCGCCGTGGTGAGCCTGGACAGGGATTTCGCCCGGTTTGCCT
CGGTGCGCCACATTCGCCCGCCGCTCTAG

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9882.00 Da        Isoelectric Point: 5.1570

>AT196169 WP_112585195.1 NZ_CP071312:1210026-1210286 [Rhizobium sp. X9]
MPHIAKIFQSGNSQAVRLPKDFRFDVEEVEVSREGDAVILRPRPDTTRRWASLHAAVERGFSADFMAEGRDQPKEQDRPE
LDQAFQ

Download         Length: 261 bp

>AT196169 NZ_CP095022:839815-840072 [Mycobacterium tuberculosis]
ATGCGCACCACGGTGTCAATCTCCGATGAAATACTCGCTGCCGCCAAACGCCGGGCCCGCGAGCGTGGTCAATCGCTGGG
CGCTGTGATCGAGGACGCCCTTCGGCGGGAGTTCGCCGCCGCCCACGTCGGCGGCGCCCGCCCGACCGTCCCGGTTTTCG
ACGGCGGCACCGGTCCGCGGCGAGGCATCGACCTGACCTCGAATAGAGCGTTGTCCGAAGTGCTCGACGAGGGCCTGGAA
CTGAACTCCCGGAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References