Detailed information of TA system TA196167

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /BrnT(toxin)
• Location: 2101409..2101901
• Replicon: chromosome
• Accession: NZ_CP071311
• Organism: Rhizobium sp. X9

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: JZY08_RS10310
• Protein ID: WP_003494557.1
• Coordinates: 2101632..2101901 (-)
• Length: 90 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: JZY08_RS10305
• Protein ID: WP_216330079.1
• Coordinates: 2101409..2101651 (-)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JZY08_RS10285	2096652..2097644	+	993	WP_137038051.1	glutathione S-transferase family protein	-
JZY08_RS10290	2097660..2098151	-	492	WP_137038052.1	NUDIX domain-containing protein	-
JZY08_RS10295	2098218..2099168	+	951	WP_003494563.1	metallophosphoesterase	-
JZY08_RS10300	2099381..2101090	-	1710	WP_216330078.1	2-isopropylmalate synthase	-
JZY08_RS10305	2101409..2101651	-	243	WP_216330079.1	CopG family antitoxin	Antitoxin
JZY08_RS10310	2101632..2101901	-	270	WP_003494557.1	BrnT family toxin	Toxin
JZY08_RS10315	2101936..2103114	-	1179	WP_216330080.1	benzoate/H(+) symporter BenE family transporter	-
JZY08_RS10320	2103080..2103334	+	255	WP_164055984.1	hypothetical protein	-
JZY08_RS10325	2103401..2104483	+	1083	WP_216330081.1	esterase-like activity of phytase family protein	-
JZY08_RS10330	2104567..2105211	-	645	WP_137038056.1	NrsF family protein	-
JZY08_RS10335	2105208..2105723	-	516	WP_035242750.1	sigma-70 family RNA polymerase sigma factor	-
JZY08_RS10340	2105942..2106199	+	258	WP_003494546.1	pentapeptide MXKDX repeat protein	-
JZY08_RS10345	2106299..2106880	-	582	WP_035242113.1	ATP-dependent Clp protease proteolytic subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (5-80)

Antitoxin

• CopG antitoxin (10-71)

Sequences

Toxin

Protein

• Length: 90 a.a.
• Molecular weight: 10808.23 Da
• Isoelectric Point: 8.8934

>T196167 WP_003494557.1 NZ_CP071311:c2101901-2101632 [Rhizobium sp. X9]
MDFEFDPAKSESNKDKHGIDFVEARALWLDEKRLVVPLETTSEERYIMIAQLRGKCWSAVYTYRNDRLRIISVRRSRDKE
KHRYEDDKR

Nucleotide

• Length: 270 bp

>T196167 NZ_CP095022:c754659-754222 [Mycobacterium tuberculosis]
ATGATAGTGCTCGACACCACCGTCCTCGTCTATGCCAAAGGCGCCGAGCATCCACTCCGCGATCCCTGCCGCGATCTCGT
CGCGGCAATCGCCGACGAACGCATCGCTGCGACCACCACCGCCGAGGTGATCCAGGAGTTCGTCCACGTACGCGCCCGCC
GGCGCGACCGCAGCGACGCCGCCGCGCTGGGCCGTGTGACTATGCCGAACTGCTCTCGCCGCTACTCACCATCAATCGAG
GCCACCTCGAAGCGCGGCCTGACGCTGTTCGAGACAACGCCAGGGCTTGAAGCCTGCGACGCGGTGCTCGCGGCGGTTGC
CGCAAGCGCCGGCGCGACCGCTCTTGTCTCGGCTGACCCGGCGTTCGCCGATCTGTCGGATGTCGTGCACGTCATTCCCG
ACGCGGCCGGGATGGTCAGCCTGCTCGGCGACCGCTGA

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 9234.34 Da
• Isoelectric Point: 4.2784

>AT196167 WP_216330079.1 NZ_CP071311:c2101651-2101409 [Rhizobium sp. X9]
MKTISVEDFDKKFDDGEDLDDYVDWSKATRPGLELVHVDVDLPEEVLRRVDAEAARLGTTRQSLMAEWIAERLESVRQVK

Nucleotide

• Length: 243 bp

>AT196167 NZ_CP095022:c754112-753867 [Mycobacterium tuberculosis]
ATGCTCAGCTTCCGCGCCGACGACCACGACGTCGACCTGGCCGACGCGTGGGCGCGTCGCCTACACATCGGCCGCTCCGA
GCTGCTGCGCGATGCGCTGCGACGTCACTTGGCCGCGCTGGCCGCGGACCAGGATGTCCAGGCCTACACCGAGCGACCGT
TGACGGACGACGAGAACGCACTGGCTGAGATCGCCGACTGGGGGCCGGCGGAGGACTGGGCCGACTGGGCCGATGCGGCG
CGGTGA