196160

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) abiEi-abiEii/AbiEii-AbiEi
Location 1009126..1010558 Replicon chromosome
Accession NZ_CP071305
Organism Streptococcus suis strain SC183

Toxin (Protein)


Gene name abiEi Uniprot ID A0A6B9RGA2
Locus tag JZY07_RS05055 Protein ID WP_024412121.1
Coordinates 1009126..1009971 (-) Length 282 a.a.

Antitoxin (Protein)


Gene name abiEii Uniprot ID Q8DZ36
Locus tag JZY07_RS05060 Protein ID WP_000037239.1
Coordinates 1009968..1010558 (-) Length 197 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JZY07_RS05050 1006263..1009064 + 2802 WP_024412122.1 CHAP domain-containing protein -
JZY07_RS05055 1009126..1009971 - 846 WP_024412121.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
JZY07_RS05060 1009968..1010558 - 591 WP_000037239.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(33-256)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(6-50)


Sequences

Toxin        


Download         Length: 282 a.a.        Molecular weight: 32427.13 Da        Isoelectric Point: 5.4446

>T196160 WP_024412121.1 NZ_CP071305:c1009971-1009126 [Streptococcus suis]
MNKAKLTALCHKISKNTGLTFNSVMTYYFLEVILKKLSQSTYSNHYIFKGGFLLSNVIGVESRSTVDIDFLFHQITLSEE
TVKQQLEEVLADSEKGISFTIQSITAIKESDEYGGYRATILCQLENIKQVIHLDIATGDVVTPQPITYDYKAIFDEDNFP
IIAYTIETILAEKLQTIYSRNFLNSRSKDFYDVYIISKLKKEDIDFIQLKNACQRTFSYRETELDFVKIIELLERFKSDP
IQNKQWQNYSKKNSYTKGISLADVLDEMIRLITVLISINSD

Download         Length: 846 bp

>T196160 NZ_CP095022:c695921-695508 [Mycobacterium tuberculosis]
GTGAAACCGCCGCTGGCAGTGGACACCAGCGTCGCGATTCCGTTGCTGGTACGGACCCATACCGCGCATGCGGCGGTTGT
CGCCTGGTGGGCACATCGGGAGGCCGCGCTGTGCGGGCACGCCCTGGCCGAAACCTACTCCGTGCTGACCCGCCTGCCGC
GTGACCTACGACTGGCACCGATGGACGCCGCGCGGCTTCTTACCGAACGCTTTGCGGCACCGCTGTTGTTGAGTTCCCGC
ACCACTGAACATCTCCCACGCGTGCTGGCCCAATTCGAGATCACTGGTGGCGCGGTCTATGACGCTCTCGTGGCCCTTGC
CGCCGCCGAGCACCGGGCTGAACTCGCCACACGCGATGCTCGAGCCAAGGACACTTACGAAAAGATCGGCGTCCACGTCG
TTGTCGCCGCGTGA

Antitoxin


Download         Length: 197 a.a.        Molecular weight: 23074.63 Da        Isoelectric Point: 7.8056

>AT196160 WP_000037239.1 NZ_CP071305:c1010558-1009968 [Streptococcus suis]
MSKKEILLDFIEKNNGIVTNKDCKALGIPTIYLTRLEKEGIIFRVEKGIFLTQNGDYDEYYFFQYRFPKAIFSYISALYL
QQFTDEIPQYFDVTVPRGYRFNTPPANLNIHFVSKEYSELGMTTVPTPMGNNVRVYDFERIICDFVIHREKIDSELFVKT
LQSYGNYPKKNLAKLYEYATKMNTLEKVKQTLEVLI

Download         Length: 591 bp

>AT196160 NZ_CP095022:c696154-695918 [Mycobacterium tuberculosis]
ATGAAGGCTGTTGTGGATGCGGCTGGCCGCATCGTCGTACCCAAACCGCTGCGCGAAGCCTTGGGGCTGCAACCGGGGTC
CACCGTGGAAATATCCCGCTATGGCGCTGGTCTCCACCTGATTCCCACCGGACGAACAGCGCGTCTCGAAGAGGAGAATG
GCGTACTGGTGGCCACCGGTGAGACCACGATCGACGATGAGGTCGTGTTCGGCCTTATCGATAGCGGCCGGAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6B9RGA2

Antitoxin

Source ID Structure
PDB 6Y8Q
AlphaFold DB A0A2I7ZET8

References