Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1698331..1698476 Replicon chromosome
Accession NZ_CP071279
Organism Klebsiella pneumoniae subsp. pneumoniae strain SA-KpST14

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1698367..1698469 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1698331..1698476 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JZ794_RS08360 1693461..1695521 + 2061 WP_004151449.1 oligopeptidase B -
JZ794_RS08365 1695525..1696184 - 660 WP_043906809.1 exodeoxyribonuclease X -
JZ794_RS08370 1696263..1696493 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JZ794_RS08375 1696606..1696980 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JZ794_RS08380 1696984..1697853 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
JZ794_RS08385 1697870..1698208 + 339 WP_002911404.1 YebY family protein -
- 1698331..1698476 - 146 - - Antitoxin
- 1698367..1698469 + 103 - - Toxin
JZ794_RS08390 1698845..1698988 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JZ794_RS08395 1699093..1700061 - 969 WP_004151446.1 VirK/YbjX family protein -
JZ794_RS08400 1700218..1700871 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
JZ794_RS08405 1700868..1701059 - 192 WP_002911395.1 YebW family protein -
JZ794_RS08410 1701157..1701396 - 240 WP_002911393.1 YebV family protein -
JZ794_RS08415 1701512..1702945 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T196139 NZ_CP071279:1698367-1698469 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT196139 NZ_CP071279:c1698476-1698331 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References