Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2171702..2171973 Replicon chromosome
Accession NZ_CP071259
Organism Escherichia coli strain MEI005

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2171832..2171935 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2171702..2171973 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J0G24_RS10480 2168257..2168919 - 663 WP_000944256.1 exodeoxyribonuclease X -
J0G24_RS10485 2168943..2169599 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
J0G24_RS10490 2169701..2169931 - 231 WP_000916763.1 DNA polymerase III subunit theta -
J0G24_RS10495 2170070..2170444 + 375 WP_000204700.1 CopC domain-containing protein YobA -
J0G24_RS10500 2170448..2171320 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
J0G24_RS10505 2171333..2171674 + 342 WP_000976472.1 YebY family protein -
- 2171702..2171973 - 272 - - Antitoxin
- 2171832..2171935 + 104 - - Toxin
J0G24_RS10510 2172070..2172726 + 657 WP_000812712.1 protein-serine/threonine phosphatase -
J0G24_RS10515 2172727..2172918 - 192 WP_001296140.1 YebW family protein -
J0G24_RS10520 2173023..2173259 - 237 WP_001295499.1 YebV family protein -
J0G24_RS10525 2173377..2174816 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T196039 NZ_CP071259:2171832-2171935 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT196039 NZ_CP071259:c2171973-2171702 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References