Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2029775..2029920 Replicon chromosome
Accession NZ_CP071252
Organism Klebsiella pneumoniae strain MEI006

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2029811..2029913 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2029775..2029920 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J0G26_RS09715 2024905..2026965 + 2061 WP_032419805.1 oligopeptidase B -
J0G26_RS09720 2026969..2027628 - 660 WP_002911407.1 exodeoxyribonuclease X -
J0G26_RS09725 2027707..2027937 - 231 WP_002911406.1 DNA polymerase III subunit theta -
J0G26_RS09730 2028050..2028424 + 375 WP_020316569.1 CopC domain-containing protein YobA -
J0G26_RS09735 2028428..2029297 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
J0G26_RS09740 2029314..2029652 + 339 WP_002911404.1 YebY family protein -
- 2029775..2029920 - 146 - - Antitoxin
- 2029811..2029913 + 103 - - Toxin
J0G26_RS09745 2030288..2030431 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
J0G26_RS09750 2030536..2031504 - 969 WP_014907334.1 VirK/YbjX family protein -
J0G26_RS09755 2031661..2032314 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
J0G26_RS09760 2032311..2032502 - 192 WP_002911395.1 YebW family protein -
J0G26_RS09765 2032600..2032839 - 240 WP_002911393.1 YebV family protein -
J0G26_RS09770 2032955..2034388 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T196015 NZ_CP071252:2029811-2029913 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT196015 NZ_CP071252:c2029920-2029775 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References