Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/YafQ-DinJ |
Location | 589790..590355 | Replicon | chromosome |
Accession | NZ_CP071248 | ||
Organism | Bifidobacterium longum subsp. infantis strain JCM 7009 |
Toxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | BLI009_RS02435 | Protein ID | WP_206648901.1 |
Coordinates | 589790..590080 (-) | Length | 97 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | B7GSH1 |
Locus tag | BLI009_RS02440 | Protein ID | WP_012576473.1 |
Coordinates | 590077..590355 (-) | Length | 93 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BLI009_RS02420 | 585649..587289 | - | 1641 | WP_206648899.1 | ABC transporter permease subunit | - |
BLI009_RS02425 | 587303..588343 | - | 1041 | WP_206648900.1 | extracellular solute-binding protein | - |
BLI009_RS02430 | 588500..589381 | - | 882 | WP_082247995.1 | MurR/RpiR family transcriptional regulator | - |
BLI009_RS02435 | 589790..590080 | - | 291 | WP_206648901.1 | type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family | Toxin |
BLI009_RS02440 | 590077..590355 | - | 279 | WP_012576473.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
BLI009_RS02445 | 590778..591119 | + | 342 | WP_206648902.1 | hypothetical protein | - |
BLI009_RS02450 | 591138..591422 | - | 285 | WP_206648903.1 | transposase | - |
BLI009_RS02455 | 591729..592373 | + | 645 | WP_206648904.1 | hypothetical protein | - |
BLI009_RS02460 | 592795..593349 | - | 555 | WP_206649259.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | - | 580858..602408 | 21550 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 97 a.a. Molecular weight: 10897.62 Da Isoelectric Point: 10.2245
>T196005 WP_206648901.1 NZ_CP071248:c590080-589790 [Bifidobacterium longum subsp. infantis]
MSSIRYTVKTTSRFRKDFKLARRRGLDAGLFKQVVSILSEGGTLPDRYHDHALTGNMTGFRECHITPDLLLVYLIEKDVL
VLTLTRTGTHSDLFGK
MSSIRYTVKTTSRFRKDFKLARRRGLDAGLFKQVVSILSEGGTLPDRYHDHALTGNMTGFRECHITPDLLLVYLIEKDVL
VLTLTRTGTHSDLFGK
Download Length: 291 bp
>T196005 NZ_CP094997:5293829-5294212 [Dyadobacter chenwenxiniae]
TTGAATATACTTTTAGATACACACGCACTGATCTGGTTTCTTGAAGGCGATGCAAATTTGTCCGAAAATGCGCTTGAAGC
AATCGAAAACAAAGACAATAAGAAATATGTTAGCATTGCTTCGCTTTGGGAAATCGCTATTAAAATCAGTTTGGGTAAAC
TCTCTCTTCAAAACTCCCTCGATCTTTTTCTTGAAGAACTCGTAGAATCAGATATTCATATTTTGCCGATATCTATAAAG
CATATCCTGCTTTTAAGTGAATTTGACTTTTTTCACAAGGACCCCTTTGATCGTCTTATCATTGCACAAGGAATAACTGA
ACACTTTGTGATTATTTCGAAAGACTCCAACTTTCTGCTTTATTCGGTTGAACTTCATTGGTAA
TTGAATATACTTTTAGATACACACGCACTGATCTGGTTTCTTGAAGGCGATGCAAATTTGTCCGAAAATGCGCTTGAAGC
AATCGAAAACAAAGACAATAAGAAATATGTTAGCATTGCTTCGCTTTGGGAAATCGCTATTAAAATCAGTTTGGGTAAAC
TCTCTCTTCAAAACTCCCTCGATCTTTTTCTTGAAGAACTCGTAGAATCAGATATTCATATTTTGCCGATATCTATAAAG
CATATCCTGCTTTTAAGTGAATTTGACTTTTTTCACAAGGACCCCTTTGATCGTCTTATCATTGCACAAGGAATAACTGA
ACACTTTGTGATTATTTCGAAAGACTCCAACTTTCTGCTTTATTCGGTTGAACTTCATTGGTAA
Antitoxin
Download Length: 93 a.a. Molecular weight: 10202.63 Da Isoelectric Point: 6.3216
>AT196005 WP_012576473.1 NZ_CP071248:c590355-590077 [Bifidobacterium longum subsp. infantis]
MSGTTTTVNVRMNAELKKQAEELFGELGMNLTTAVNIFIRQSLRQGGIPFNVSLDEPNRETVSAMLEAKRIARDGNVKGY
RDLNALFKDLDA
MSGTTTTVNVRMNAELKKQAEELFGELGMNLTTAVNIFIRQSLRQGGIPFNVSLDEPNRETVSAMLEAKRIARDGNVKGY
RDLNALFKDLDA
Download Length: 279 bp
>AT196005 NZ_CP094997:5293638-5293832 [Dyadobacter chenwenxiniae]
ATGAAAAAGGTATCAGTTCTTCCTGAGAATTTGAAAGAGGAGGTGTCCGACTATGTGGACTTCTTAATCAGCAAATATCT
CCCAGGCGAAAGTGTAAACAAAAAGCCGTTGAAGTTTGGGATGATGAAGGGAACGTTTAAAATGAGCCCTGATTTTGATG
AGCCTTTGGATGACTTTAAAGAATACATGCCTTGA
ATGAAAAAGGTATCAGTTCTTCCTGAGAATTTGAAAGAGGAGGTGTCCGACTATGTGGACTTCTTAATCAGCAAATATCT
CCCAGGCGAAAGTGTAAACAAAAAGCCGTTGAAGTTTGGGATGATGAAGGGAACGTTTAAAATGAGCCCTGATTTTGATG
AGCCTTTGGATGACTTTAAAGAATACATGCCTTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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