Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 589790..590355 Replicon chromosome
Accession NZ_CP071248
Organism Bifidobacterium longum subsp. infantis strain JCM 7009

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BLI009_RS02435 Protein ID WP_206648901.1
Coordinates 589790..590080 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID B7GSH1
Locus tag BLI009_RS02440 Protein ID WP_012576473.1
Coordinates 590077..590355 (-) Length 93 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BLI009_RS02420 585649..587289 - 1641 WP_206648899.1 ABC transporter permease subunit -
BLI009_RS02425 587303..588343 - 1041 WP_206648900.1 extracellular solute-binding protein -
BLI009_RS02430 588500..589381 - 882 WP_082247995.1 MurR/RpiR family transcriptional regulator -
BLI009_RS02435 589790..590080 - 291 WP_206648901.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
BLI009_RS02440 590077..590355 - 279 WP_012576473.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
BLI009_RS02445 590778..591119 + 342 WP_206648902.1 hypothetical protein -
BLI009_RS02450 591138..591422 - 285 WP_206648903.1 transposase -
BLI009_RS02455 591729..592373 + 645 WP_206648904.1 hypothetical protein -
BLI009_RS02460 592795..593349 - 555 WP_206649259.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 580858..602408 21550


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-94)

Antitoxin

(6-70)


Sequences


Toxin        


Download         Length: 97 a.a.        Molecular weight: 10897.62 Da        Isoelectric Point: 10.2245

>T196005 WP_206648901.1 NZ_CP071248:c590080-589790 [Bifidobacterium longum subsp. infantis]
MSSIRYTVKTTSRFRKDFKLARRRGLDAGLFKQVVSILSEGGTLPDRYHDHALTGNMTGFRECHITPDLLLVYLIEKDVL
VLTLTRTGTHSDLFGK

Download         Length: 291 bp

>T196005 NZ_CP094997:5293829-5294212 [Dyadobacter chenwenxiniae]
TTGAATATACTTTTAGATACACACGCACTGATCTGGTTTCTTGAAGGCGATGCAAATTTGTCCGAAAATGCGCTTGAAGC
AATCGAAAACAAAGACAATAAGAAATATGTTAGCATTGCTTCGCTTTGGGAAATCGCTATTAAAATCAGTTTGGGTAAAC
TCTCTCTTCAAAACTCCCTCGATCTTTTTCTTGAAGAACTCGTAGAATCAGATATTCATATTTTGCCGATATCTATAAAG
CATATCCTGCTTTTAAGTGAATTTGACTTTTTTCACAAGGACCCCTTTGATCGTCTTATCATTGCACAAGGAATAACTGA
ACACTTTGTGATTATTTCGAAAGACTCCAACTTTCTGCTTTATTCGGTTGAACTTCATTGGTAA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10202.63 Da        Isoelectric Point: 6.3216

>AT196005 WP_012576473.1 NZ_CP071248:c590355-590077 [Bifidobacterium longum subsp. infantis]
MSGTTTTVNVRMNAELKKQAEELFGELGMNLTTAVNIFIRQSLRQGGIPFNVSLDEPNRETVSAMLEAKRIARDGNVKGY
RDLNALFKDLDA

Download         Length: 279 bp

>AT196005 NZ_CP094997:5293638-5293832 [Dyadobacter chenwenxiniae]
ATGAAAAAGGTATCAGTTCTTCCTGAGAATTTGAAAGAGGAGGTGTCCGACTATGTGGACTTCTTAATCAGCAAATATCT
CCCAGGCGAAAGTGTAAACAAAAAGCCGTTGAAGTTTGGGATGATGAAGGGAACGTTTAAAATGAGCCCTGATTTTGATG
AGCCTTTGGATGACTTTAAAGAATACATGCCTTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB A0A0A8MHE5

References