Detailed information of TA system TA196004

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tacAT/GNAT-DUF1778
• Location: 1989520..1990306
• Replicon: chromosome
• Accession: NZ_CP071246
• Organism: Corynebacterium sp. CNCTC7651

Toxin (Protein)

• Gene name: tacT
• Uniprot ID: -
• Locus tag: JZY91_RS09570
• Protein ID: WP_234947647.1
• Coordinates: 1989520..1990032 (-)
• Length: 171 a.a.

Antitoxin (Protein)

• Gene name: tacA
• Uniprot ID: -
• Locus tag: JZY91_RS09575
• Protein ID: WP_234947648.1
• Coordinates: 1990022..1990306 (-)
• Length: 95 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JZY91_RS09565 (JZY91_09540)	1985471..1989475	+	4005	WP_234947646.1	non-ribosomal peptide synthetase	-
JZY91_RS09570 (JZY91_09545)	1989520..1990032	-	513	WP_234947647.1	GNAT family N-acetyltransferase	Toxin
JZY91_RS09575 (JZY91_09550)	1990022..1990306	-	285	WP_234947648.1	DUF1778 domain-containing protein	Antitoxin
JZY91_RS09580 (JZY91_09555)	1990476..1991360	+	885	WP_234947649.1	transporter substrate-binding domain-containing protein	-
JZY91_RS09585 (JZY91_09560)	1991395..1992048	+	654	WP_255695742.1	amino acid ABC transporter permease	-
JZY91_RS09590 (JZY91_09565)	1992038..1992709	+	672	WP_234947650.1	amino acid ABC transporter permease	-
JZY91_RS09595 (JZY91_09570)	1992710..1993444	+	735	WP_234947651.1	amino acid ABC transporter ATP-binding protein	-
JZY91_RS09600 (JZY91_09575)	1993590..1994249	+	660	WP_234947652.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (24-141)

Antitoxin

• Vibrio phage ICP1, Orf50 (7-72)

Sequences

Toxin

Protein

• Length: 171 a.a.
• Molecular weight: 18793.53 Da
• Isoelectric Point: 7.2151

>T196004 WP_234947647.1 NZ_CP071246:c1990032-1989520 [Corynebacterium sp. CNCTC7651]
MTADNVLQPPRRLEKSDNRKDFSSGEPSLDIWFHRYAMQNQRARNCVVYVSTWNDRVMGYYAVCTGSVEKELAPEDFASG
RPRAIPVVILARLAVDQRAQGKGIGRALLRDALTRCLAGSEAIGAAAVVVHALNEEAKQFYLSAADFIELPGEPLHLMLP
IAQIARALQE

Nucleotide

• Length: 513 bp

>T196004 NZ_CP094997:4947062-4947640 [Dyadobacter chenwenxiniae]
ATGATTCATTCCGCGAGGTTTGTAGCAATCCTCGACGCCTGCGTGCTTTATCCAGCACCAATACGGGACTTGCTGCTATA
CCTTGCAGATGCGGAATTGTACACTCCAAAATGGACTGACAAAATTCACGAAGAATGGACGCAGAGCTTGCTGAAGAAGA
GGTCGGATATTTCATCCGAACAACTGCGAAAAACGATCGCCGCTATGCATAATGCCTTTCCCGATGCCAATGTATTGAAC
TACCAGTCGCTAATGAAATCGCTTGAGTTGCCAGATCCCAATGACGCACATGTCCTTGCCGCAGCTGTGCGCTGTAATGC
CGATGTCCTTGTAACTGCCAATATAAAAGACTTTCCAAAGGAATACCTGCAACAATTTGATATTGAGCCACAACACCCGG
ATGTTTTTATTTCAAACCTGATCGAATTAAACCCGGATAATACTTTGAAAGCATTTGAAAATCAGGTCGGGAATTTGAGA
AAACCATCTCTAACAGCATGTGCGGTTCTTGACAAACTGGAAAAAGTAGGTTTGATAAAAACATCTAGCATGTTTCTGCG
GCTGATGCAATCACTCTAG

Antitoxin

Protein

• Length: 95 a.a.
• Molecular weight: 10664.02 Da
• Isoelectric Point: 4.8552

>AT196004 WP_234947648.1 NZ_CP071246:c1990306-1990022 [Corynebacterium sp. CNCTC7651]
MTIKDQRLNLRATSAQNELLRRAAEATEQSVSEFVLSSAVHEAEIVLADKRRFVLDQADFDVFRHALDQPIRVGKLAALF
AEPDVFGQEFSFDR

Nucleotide

• Length: 285 bp

>AT196004 NZ_CP094997:4946616-4947065 [Dyadobacter chenwenxiniae]
ATGGAAACTGTATTAGAAAGGCCAACAAAACGAGAACAGAAAATGGCAAGCGAATCGGTAACAAACTTTACTTCTGCGAT
ATCGAGGCGAAAGTCCGATACTGTCAACATTAGGATTCAGGAAAGTGAGGAATTGTTTACGATACCCAGGAGAGCGCTCG
AATTTCTTTCACATATCCTGTCTATAATGGCAGAGGGGAAGGCGATTTCAGTATTCCCATCTGAATCTGAACTTAGTACG
CAGCAAGCTGCCGACATTCTCCATGTGTCCCGGCCACATATTGTGAAGCTGCTCGAACAAGGAGTTATTCCATTCAAAAA
AGCAGGCAGTCACAGGAGGATTTTGCTGGAAGACCTCATGAAACATGCCGCAATGCAAAAAGAAACAACAAGAAAAAGCC
TTAAATTTCTTGTCGAACAGGCGCAGGATTTAAATCTGGGTTACGAATGA