196002

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 1319495..1320014 Replicon chromosome
Accession NZ_CP071246
Organism Corynebacterium sp. CNCTC7651

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag JZY91_RS06385 Protein ID WP_234947048.1
Coordinates 1319495..1319779 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag JZY91_RS06390 Protein ID WP_234947049.1
Coordinates 1319763..1320014 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JZY91_RS06365 (JZY91_06350) 1314760..1315458 + 699 WP_234947045.1 transcriptional repressor LexA -
JZY91_RS06370 (JZY91_06355) 1315549..1316276 + 728 Protein_1238 DeoR/GlpR family DNA-binding transcription regulator -
JZY91_RS06375 (JZY91_06360) 1316382..1317365 + 984 WP_234947046.1 1-phosphofructokinase family hexose kinase -
JZY91_RS06380 (JZY91_06365) 1317390..1319498 + 2109 WP_234947047.1 fructose-specific PTS transporter subunit EIIC -
JZY91_RS06385 (JZY91_06370) 1319495..1319779 - 285 WP_234947048.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JZY91_RS06390 (JZY91_06375) 1319763..1320014 - 252 WP_234947049.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
JZY91_RS06395 (JZY91_06380) 1320129..1320398 + 270 WP_234947050.1 HPr family phosphocarrier protein -
JZY91_RS06400 (JZY91_06385) 1320431..1321813 - 1383 WP_234947051.1 solute carrier family 23 protein -
JZY91_RS06405 (JZY91_06390) 1321830..1322747 - 918 WP_234947052.1 dihydrodipicolinate synthase family protein -
JZY91_RS06410 (JZY91_06395) 1322773..1323609 - 837 WP_234947053.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

Antitoxin ParD

(1-80)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10923.39 Da        Isoelectric Point: 6.2243

>T196002 WP_234947048.1 NZ_CP071246:c1319779-1319495 [Corynebacterium sp. CNCTC7651]
MSFRLKEEAVQDLREIWTYSADNWGADQADNYIRAIEGTIREVAKNPEKGKSTPLLPGFNWLSVRRHVIFYGQDEEGVVI
VRILHQRMDPSLHL

Download         Length: 285 bp

>T196002 NZ_CP094993:c16874-16524 [Klebsiella pneumoniae]
ATGTGGGTCATCGAGACAACTGACACCTTTGATGAGTGGTTCGATGCACTGGATGATACCGATAGAGCCAACGTGCTGGC
TTCGATGATGGTGCTGCGAGATAGAGGTCCCATGCTGTCGAGACCATACGCGGATACTGTTAACGGTTCATCCTACAGCA
ACATGAAAGAGCTGCGGGTCCAAAGCAAAGGAGATCCTATCAGGGCATTCTTTGCGTTCGATCCAAAGCGTAAGGGGATT
CTTCTCTGCGCCGGTAACAAGACCGGGGACGAGAAAAGGTTTTATGAAGTAATGATCCCAATTGCAGACCGCGAGTTTGC
GGCGCACTTGGATAAATTGAAGAAGGAGTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9276.28 Da        Isoelectric Point: 4.8047

>AT196002 WP_234947049.1 NZ_CP071246:c1320014-1319763 [Corynebacterium sp. CNCTC7651]
MAKNTSISLGNHFDSFVAQQVSTGRYATASEVVRAGLRLLEDSELRLGTLRAELEKGNRSATVEDFDFDEFLVDVRRSHE
FPA

Download         Length: 252 bp

>AT196002 NZ_CP094993:c16519-16217 [Klebsiella pneumoniae]
ATGGCAAGAACTCTTGACCAAATGCTGGCAACAGAAAAGCCTGAGGTTGTTGCCAAAGCACAGAAAGCGGCCACTGAGAT
GTTACTGAACATCCACTTGGCAGAGCTTCGTGATCGCATGAACCTTACCCAGGGGGAAATTGCTGCATCTCTGGGTGTGA
GACAGCCGACAGTCTCCGAGATGGAAAAACCTGGACGAGATCTCAAGCTGTCGTCCATTAAGCGGTACGTTGAGGCCTCC
GGTGGCAAGCTACGCCTCGATGTTGAACTTCCGGACGGCACCCACTACGGCTTTGCCGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References