Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4164018..4164687 Replicon chromosome
Accession NZ_CP071204
Organism Serratia marcescens subsp. marcescens ATCC 13880 substr. Sm_S6_jyu2015

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag J0G02_RS19885 Protein ID WP_016929976.1
Coordinates 4164018..4164440 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A8G2G4M4
Locus tag J0G02_RS19890 Protein ID WP_004931679.1
Coordinates 4164421..4164687 (-) Length 89 a.a.

Genomic Context


J0G02_RS19865J0G02_RS19895J0G02_RS19910J0G02_RS19870J0G02_RS19875J0G02_RS19880J0G02_RS19885J0G02_RS19890J0G02_RS19900J0G02_RS19905J0G02_RS19915
Location: 4159904..4160422 (519 bp)
Type: Others
Protein ID: WP_033639477.1
Location: 4165008..4166000 (993 bp)
Type: Others
Protein ID: WP_033639470.1
Location: 4167545..4168153 (609 bp)
Type: Others
Protein ID: WP_028127691.1
Location: 4160460..4161824 (1365 bp)
Type: Others
Protein ID: WP_033639476.1
Location: 4161905..4163323 (1419 bp)
Type: Others
Protein ID: WP_033639474.1
Location: 4163320..4164018 (699 bp)
Type: Others
Protein ID: WP_033639472.1
Location: 4164018..4164440 (423 bp)
Type: Toxin
Protein ID: WP_016929976.1
Location: 4164421..4164687 (267 bp)
Type: Antitoxin
Protein ID: WP_004931679.1
Location: 4166039..4166536 (498 bp)
Type: Others
Protein ID: WP_033639468.1
Location: 4166687..4167361 (675 bp)
Type: Others
Protein ID: WP_033639467.1
Location: 4168194..4169120 (927 bp)
Type: Others
Protein ID: WP_033639466.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
J0G02_RS198654159904..4160422+519WP_033639477.1flavodoxin FldB-
J0G02_RS198704160460..4161824-1365WP_033639476.1cell envelope integrity protein CreD-
J0G02_RS198754161905..4163323-1419WP_033639474.1two-component system sensor histidine kinase CreC-
J0G02_RS198804163320..4164018-699WP_033639472.1two-component system response regulator CreB-
J0G02_RS198854164018..4164440-423WP_016929976.1protein YgfXToxin
J0G02_RS198904164421..4164687-267WP_004931679.1FAD assembly factor SdhEAntitoxin
J0G02_RS198954165008..4166000+993WP_033639470.1tRNA-modifying protein YgfZ-
J0G02_RS199004166039..4166536-498WP_033639468.1DUF2165 domain-containing protein-
J0G02_RS199054166687..4167361-675WP_033639467.1hemolysin III family protein-
J0G02_RS199104167545..4168153+609WP_028127691.1HD domain-containing protein-
J0G02_RS199154168194..4169120-927WP_033639466.1ribokinase-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(2-131)

Antitoxin

(7-79)


Sequences


Toxin        


Download         Length: 141 a.a.        Molecular weight: 16501.62 Da        Isoelectric Point: 11.2159

>T195674 WP_016929976.1 NZ_CP071204:c4164440-4164018 [Serratia marcescens subsp. marcescens ATCC 13880]
VAQWRCDIRISWRTQLFSLLTHGVLILLILISPWPEGFGPLWLVLLTLVVFQCIRSQKRIAAVQGELRLLADRRFSWHGR
EWRLAKKPWMPGYGMLLTLQPMEGKKRRRLWLASDCMSKEEWRHLRQLLLHPPAGNGEEP

Download         Length: 423 bp

>T195674 NZ_CP094787:c2485302-2485036 [Staphylococcus aureus]
ATGAGCAATTACACGGTTAAGATTAAAAATTCAGCGAAATCAGATTTAAAGAAAATAAAACATTCTTATTTAAAGAAGTC
ATTTTTAGAAATTGTTGAGACTTTAAAAAATGATCCGTATAAAATAACACAATCTTTTGAAAAATTAGAGCCTAAATATT
TAGAGCGATATTCAAGAAGAATTAACCATCAGCACAGGGTCGTCTATACCGTAGATGATCGAAATAAAGAAGTATTAATA
CTATCGGCATGGTCACATTATGATTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10387.89 Da        Isoelectric Point: 4.7921

>AT195674 WP_004931679.1 NZ_CP071204:c4164687-4164421 [Serratia marcescens subsp. marcescens ATCC 13880]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLNDADKALFIRLLECDDPDLFNWLMNHGAPQDGELQRMVTLIQTRN
KDRGPVAM

Download         Length: 267 bp

>AT195674 NZ_CP094787:c2485559-2485302 [Staphylococcus aureus]
ATGATTATCACTAGCCCTACAGAAGCGAGAAAAGATTTTTATCAATTACTAAAAAATGTTAATAATAATCACGAACCAAT
TTATATTAGTGGCAATAATGCCGAAAATAATGCTGTGATTATAGGTTTAGAAGATTGGAAAAGTATACAAGAGACAATAT
ATCTTGAATCTACTGGTACAATGGACAAAGTAAGAGAAAGAGAAAAAGATAATAGTGGTACAACAAATATAGATGATATT
GATTGGGATAATCTTTAA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References