Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/RelB(antitoxin) |
| Location | 1284693..1285308 | Replicon | chromosome |
| Accession | NZ_CP071145 | ||
| Organism | Streptococcus equi subsp. equi strain 470_007 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | C0M8Y9 |
| Locus tag | JZI48_RS06255 | Protein ID | WP_012680125.1 |
| Coordinates | 1284970..1285308 (+) | Length | 113 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | C0M8Z0 |
| Locus tag | JZI48_RS06250 | Protein ID | WP_012680126.1 |
| Coordinates | 1284693..1284980 (+) | Length | 96 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JZI48_RS06245 (JZI48_06245) | 1282880..1284331 | + | 1452 | WP_012680127.1 | ATP-binding protein | - |
| JZI48_RS06250 (JZI48_06250) | 1284693..1284980 | + | 288 | WP_012680126.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| JZI48_RS06255 (JZI48_06255) | 1284970..1285308 | + | 339 | WP_012680125.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| JZI48_RS11025 | 1285900..1286463 | - | 564 | Protein_1217 | transposase | - |
| JZI48_RS11030 | 1286610..1286924 | - | 315 | Protein_1218 | IS200/IS605 family transposase | - |
| JZI48_RS06270 (JZI48_06270) | 1287119..1288162 | - | 1044 | WP_012680124.1 | aldose epimerase family protein | - |
| JZI48_RS06275 (JZI48_06275) | 1288239..1289249 | - | 1011 | WP_012680123.1 | UDP-glucose 4-epimerase GalE | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 113 a.a. Molecular weight: 13203.98 Da Isoelectric Point: 4.6787
>T195470 WP_012680125.1 NZ_CP071145:1284970-1285308 [Streptococcus equi subsp. equi]
MAYDIYISNKAEQDLDEIYNYYLTEFSHSSAQKVIESLQSAISILEISPEGYVDFDDRVGRKLFPEGQLRMIPSKHFIVF
YLIRQSRVDILRIRSTKTDYLNDLENLFNNIL
MAYDIYISNKAEQDLDEIYNYYLTEFSHSSAQKVIESLQSAISILEISPEGYVDFDDRVGRKLFPEGQLRMIPSKHFIVF
YLIRQSRVDILRIRSTKTDYLNDLENLFNNIL
Download Length: 339 bp
>T195470 NZ_CP094733:2036042-2036230 [Staphylococcus epidermidis]
ATGAGCTTACATTTCCAAATTTTGCTGTGGCTTTCTATCTTATTTATCATCGCAGGAACGATATTATTGGTAACAATGCT
TAAAACTAAAAAAGAAGAACGAAAAGAATCTTATCTAGGCTTTACTGTAATTTTCTTAATCTTTGGTTTTGCCATCTTAA
TTTATACTTTTATATTCGGAATTTTATAA
ATGAGCTTACATTTCCAAATTTTGCTGTGGCTTTCTATCTTATTTATCATCGCAGGAACGATATTATTGGTAACAATGCT
TAAAACTAAAAAAGAAGAACGAAAAGAATCTTATCTAGGCTTTACTGTAATTTTCTTAATCTTTGGTTTTGCCATCTTAA
TTTATACTTTTATATTCGGAATTTTATAA
Antitoxin
Download Length: 96 a.a. Molecular weight: 10977.52 Da Isoelectric Point: 4.4777
>AT195470 WP_012680126.1 NZ_CP071145:1284693-1284980 [Streptococcus equi subsp. equi]
MATLIRDRQYNFRVNTEMMEEAKRILEAKNISVPDALNLFVERVVEEKDLPIKTAEQIRAESFLNELISELDEGYQDILA
GRTKPANEVFSKYGL
MATLIRDRQYNFRVNTEMMEEAKRILEAKNISVPDALNLFVERVVEEKDLPIKTAEQIRAESFLNELISELDEGYQDILA
GRTKPANEVFSKYGL
Download Length: 288 bp
>AT195470 NZ_CP094733:2035760-2036017 [Staphylococcus epidermidis]
ATGAAATTAAACAAAGCAAATATATTCAATTTGATATTCACCATTTTATTTTTTTCATTTAACATTCTCATAACCTATAA
CGCAAATATAGATTATAAGTTATGGTTAATACCTGGTTTAGCAATTTGTGGTTTTGCTCTTTTTTCAAGCTTGACCTTAG
TAATTATCTATAGTGATTTATTCAGTGAAATATTATTTTTTATCAACATTATCTTAGCACTGTATTACATTTATCCGATT
TTTTATGAATTTGTCTAA
ATGAAATTAAACAAAGCAAATATATTCAATTTGATATTCACCATTTTATTTTTTTCATTTAACATTCTCATAACCTATAA
CGCAAATATAGATTATAAGTTATGGTTAATACCTGGTTTAGCAATTTGTGGTTTTGCTCTTTTTTCAAGCTTGACCTTAG
TAATTATCTATAGTGATTTATTCAGTGAAATATTATTTTTTATCAACATTATCTTAGCACTGTATTACATTTATCCGATT
TTTTATGAATTTGTCTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|