Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/RelB(antitoxin) |
| Location | 931468..932083 | Replicon | chromosome |
| Accession | NZ_CP071142 | ||
| Organism | Streptococcus equi subsp. equi strain 489_004 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | C0M8Y9 |
| Locus tag | JZI57_RS04620 | Protein ID | WP_012680125.1 |
| Coordinates | 931745..932083 (+) | Length | 113 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | C0M8Z0 |
| Locus tag | JZI57_RS04615 | Protein ID | WP_012680126.1 |
| Coordinates | 931468..931755 (+) | Length | 96 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JZI57_RS04610 (JZI57_04610) | 929655..931106 | + | 1452 | WP_012680127.1 | ATP-binding protein | - |
| JZI57_RS04615 (JZI57_04615) | 931468..931755 | + | 288 | WP_012680126.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| JZI57_RS04620 (JZI57_04620) | 931745..932083 | + | 339 | WP_012680125.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| JZI57_RS11010 | 932675..933238 | - | 564 | Protein_892 | transposase | - |
| JZI57_RS11015 | 933385..933699 | - | 315 | Protein_893 | IS200/IS605 family transposase | - |
| JZI57_RS04635 (JZI57_04635) | 933894..934937 | - | 1044 | WP_012680124.1 | aldose epimerase family protein | - |
| JZI57_RS04640 (JZI57_04640) | 935014..936024 | - | 1011 | WP_012680123.1 | UDP-glucose 4-epimerase GalE | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 113 a.a. Molecular weight: 13203.98 Da Isoelectric Point: 4.6787
>T195463 WP_012680125.1 NZ_CP071142:931745-932083 [Streptococcus equi subsp. equi]
MAYDIYISNKAEQDLDEIYNYYLTEFSHSSAQKVIESLQSAISILEISPEGYVDFDDRVGRKLFPEGQLRMIPSKHFIVF
YLIRQSRVDILRIRSTKTDYLNDLENLFNNIL
MAYDIYISNKAEQDLDEIYNYYLTEFSHSSAQKVIESLQSAISILEISPEGYVDFDDRVGRKLFPEGQLRMIPSKHFIVF
YLIRQSRVDILRIRSTKTDYLNDLENLFNNIL
Download Length: 339 bp
>T195463 NZ_CP094731:876300-876509 [Staphylococcus epidermidis]
ATGAAATTGAAAAAAGGATTGATACATGTTTCAGGTATTAAAACAACTGAACAAGAGAAACAGCTCAAAGATCATTTATC
TAAGATGATAGGCATCAATAGTGTGGATATCGATTACCAAATGAATGAGATTCGAGTGGAATTTGACACTCCCGCAAATT
TAAATAACATTGAAAAAGAAATTTACGATTGCGGATTTCGTATTTTATAA
ATGAAATTGAAAAAAGGATTGATACATGTTTCAGGTATTAAAACAACTGAACAAGAGAAACAGCTCAAAGATCATTTATC
TAAGATGATAGGCATCAATAGTGTGGATATCGATTACCAAATGAATGAGATTCGAGTGGAATTTGACACTCCCGCAAATT
TAAATAACATTGAAAAAGAAATTTACGATTGCGGATTTCGTATTTTATAA
Antitoxin
Download Length: 96 a.a. Molecular weight: 10977.52 Da Isoelectric Point: 4.4777
>AT195463 WP_012680126.1 NZ_CP071142:931468-931755 [Streptococcus equi subsp. equi]
MATLIRDRQYNFRVNTEMMEEAKRILEAKNISVPDALNLFVERVVEEKDLPIKTAEQIRAESFLNELISELDEGYQDILA
GRTKPANEVFSKYGL
MATLIRDRQYNFRVNTEMMEEAKRILEAKNISVPDALNLFVERVVEEKDLPIKTAEQIRAESFLNELISELDEGYQDILA
GRTKPANEVFSKYGL
Download Length: 288 bp
>AT195463 NZ_CP094731:876000-876293 [Staphylococcus epidermidis]
ATGGCAGACATGGAGAGTGCACATCACTCAGAGCAAATAAAAACAAATTTAAAATCAAGATTAAATAGAATAGAAGGTCA
AGTAAGAGCAATCAATCGTATGATTGATGACGATGTTTACTGTGATGATGTACTAACTCAAATTAGAGCAACACGTTCAG
CATTGAATAGTGTAGCTATTAAATTACTAGATCATCACATGAAGGGTTGTATTATGGAAAAAATAAACGACGGTGCGCAA
GAAGAAGCAATGGATGAATTGCTCGTGACATTCCAAAAATTAATAAAAGATTAA
ATGGCAGACATGGAGAGTGCACATCACTCAGAGCAAATAAAAACAAATTTAAAATCAAGATTAAATAGAATAGAAGGTCA
AGTAAGAGCAATCAATCGTATGATTGATGACGATGTTTACTGTGATGATGTACTAACTCAAATTAGAGCAACACGTTCAG
CATTGAATAGTGTAGCTATTAAATTACTAGATCATCACATGAAGGGTTGTATTATGGAAAAAATAAACGACGGTGCGCAA
GAAGAAGCAATGGATGAATTGCTCGTGACATTCCAAAAATTAATAAAAGATTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|