Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1940616..1940761 Replicon chromosome
Accession NZ_CP071080
Organism Klebsiella pneumoniae strain 3347684I

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1940652..1940754 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1940616..1940761 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JY393_RS09255 1935746..1937806 + 2061 WP_211652365.1 oligopeptidase B -
JY393_RS09260 1937810..1938469 - 660 WP_002911407.1 exodeoxyribonuclease X -
JY393_RS09265 1938548..1938778 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JY393_RS09270 1938891..1939265 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JY393_RS09275 1939269..1940138 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
JY393_RS09280 1940155..1940493 + 339 WP_016529031.1 YebY family protein -
- 1940616..1940761 - 146 - - Antitoxin
- 1940652..1940754 + 103 - - Toxin
JY393_RS09285 1941129..1941272 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JY393_RS09290 1941377..1942345 - 969 WP_004151446.1 VirK/YbjX family protein -
JY393_RS09295 1942502..1943155 + 654 WP_009307541.1 protein-serine/threonine phosphatase -
JY393_RS09300 1943152..1943343 - 192 WP_002911395.1 YebW family protein -
JY393_RS09305 1943441..1943680 - 240 WP_002911393.1 YebV family protein -
JY393_RS09310 1943796..1945229 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T195241 NZ_CP071080:1940652-1940754 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT195241 NZ_CP071080:c1940761-1940616 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References