Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 3954009..3954790 Replicon chromosome
Accession NZ_CP071063
Organism Enterobacter mori strain 08-091

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag JY395_RS18575 Protein ID WP_109081744.1
Coordinates 3954009..3954500 (-) Length 164 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag JY395_RS18580 Protein ID WP_042713858.1
Coordinates 3954497..3954790 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JY395_RS18555 (JY395_18540) 3949904..3950596 + 693 WP_042718993.1 response regulator -
JY395_RS18560 (JY395_18545) 3950651..3952786 - 2136 WP_215230252.1 ornithine decarboxylase -
JY395_RS18565 (JY395_18550) 3952968..3953681 + 714 WP_100166396.1 DUF554 domain-containing protein -
JY395_RS18575 (JY395_18560) 3954009..3954500 - 492 WP_109081744.1 GNAT family N-acetyltransferase Toxin
JY395_RS18580 (JY395_18565) 3954497..3954790 - 294 WP_042713858.1 DUF1778 domain-containing protein Antitoxin
JY395_RS18585 (JY395_18570) 3954892..3956685 - 1794 WP_109081743.1 hybrid sensor histidine kinase/response regulator -
JY395_RS18590 (JY395_18575) 3956682..3957314 - 633 WP_042719327.1 response regulator transcription factor -
JY395_RS18595 (JY395_18580) 3957490..3957804 + 315 WP_010435531.1 lipoprotein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(87-143)

Antitoxin

Vibrio phage ICP1, Orf50

(1-95)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 17472.23 Da        Isoelectric Point: 7.2653

>T195178 WP_109081744.1 NZ_CP071063:c3954500-3954009 [Enterobacter mori]
MISAPEPLHAGHILTPFCCGVDSMDNWLKQRAMKNQASGASRTFVCCGGDSNVLAYYSLASSAVTTNTAPGRFRRNMPDP
IPVVVLGRLAVDQSLHGQGVGRALVRDAGLRVIQVAETIGIRGMLVHALSDEAREFYLRVGFESSPMDPMILMVTLGDLV
ASI

Download         Length: 492 bp

>T195178 NZ_CP094343:3840379-3840693 [Pseudomonas sp. M1]
ATGATCTTCATCGAAACGCCAGTCTTCACGAAGCGGATTCTCGCGCTAGTAGACGATGAGACCTATCGCAAGCTTCAGGA
AGACCTAACGCTCCACCCGGACGCCGGAGCAGTCATTGAAGGCACAGGTGGCGTGCGCAAGATTCGCATTGCTGCCAATG
GCCACGGGAAAAGAGGCGGCGCCCGGGTCATCTACTACCACTTCACATCCGCCTCTCAAATTGCATTCCTGCTGGTCTAT
GACAAGACATCGCAGGAGGACCTGACTGCCGATCAGAAAAAGGTACTTCGGCAGATCGTTGAGAACTGGAGATAG

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10941.57 Da        Isoelectric Point: 9.9156

>AT195178 WP_042713858.1 NZ_CP071063:c3954790-3954497 [Enterobacter mori]
MPAANTMAVKRETLNLRIRPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIEQRIIMADPEAYQEFLARLDQAPAPN
AALRKTMQTPAPWEREK

Download         Length: 294 bp

>AT195178 NZ_CP094343:3840696-3841001 [Pseudomonas sp. M1]
ATGGACAAAGAACTCTTCGCTGAACTGGTCGAAAGCGTGACCCAGATGGACGAGATCGTGCGCGGCGAACGTCAACCTTC
CCGCGAATTCCACATCGACGCCGTGAAGGTTCGCGAAATCCGCCGCGCCACTGGCCTGTCCCAGGCCAAATTCGCCCGGA
AAATCAATGTTGCTGTCGGCACGCTGCGCAATTGGGAGCAAGGGCGCCGCGATCCCGAGGGGCCTGCTCGCGCGCTGCTC
CGAGCCATCGATAATGATCCGGTCCATGTTCTAGCTGCCCTGAATGGCGGCCCGCGAGAAGACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References