Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3869400..3870057 Replicon chromosome
Accession NZ_CP071063
Organism Enterobacter mori strain 08-091

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag JY395_RS18130 Protein ID WP_215230227.1
Coordinates 3869400..3869810 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag JY395_RS18135 Protein ID WP_042716098.1
Coordinates 3869791..3870057 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JY395_RS18110 (JY395_18095) 3865392..3867125 - 1734 WP_100166357.1 single-stranded-DNA-specific exonuclease RecJ -
JY395_RS18115 (JY395_18100) 3867131..3867844 - 714 WP_215230226.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
JY395_RS18120 (JY395_18105) 3867873..3868769 - 897 WP_042716100.1 site-specific tyrosine recombinase XerD -
JY395_RS18125 (JY395_18110) 3868871..3869392 + 522 WP_010435318.1 flavodoxin FldB -
JY395_RS18130 (JY395_18115) 3869400..3869810 - 411 WP_215230227.1 protein YgfX Toxin
JY395_RS18135 (JY395_18120) 3869791..3870057 - 267 WP_042716098.1 FAD assembly factor SdhE Antitoxin
JY395_RS18140 (JY395_18125) 3870352..3871332 + 981 WP_215230228.1 tRNA-modifying protein YgfZ -
JY395_RS18145 (JY395_18130) 3871417..3872076 - 660 WP_003863433.1 hemolysin III family protein -
JY395_RS18150 (JY395_18135) 3872242..3872553 - 312 WP_215230229.1 N(4)-acetylcytidine aminohydrolase -
JY395_RS18155 (JY395_18140) 3872604..3873335 + 732 WP_215231163.1 MurR/RpiR family transcriptional regulator -
JY395_RS18160 (JY395_18145) 3873453..3874886 + 1434 WP_215230230.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16141.00 Da        Isoelectric Point: 11.5020

>T195177 WP_215230227.1 NZ_CP071063:c3869810-3869400 [Enterobacter mori]
VVLWQSDLRVSWRSQWMSLLLHGLVAAFVLLMPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLLVDSRLRWQGK
EWEIVGTPWMLSVGMMLRLRQPEGGRRQHLWLAADSMDAAEWRDLRRMMLQQPTQD

Download         Length: 411 bp

>T195177 NZ_CP094343:c3812151-3811855 [Pseudomonas sp. M1]
ATGATCGGGAGTTTCAGGGATGCGTGGCTGGAAGCGTTCTTCGTGCGGGACAGGATGCCCCGGCAGATTCCCGCGGATAT
CCAGGAGCGCCTGTTCCGCAAGCTGCAGATGCTCGACGACGCCACCACGGACGCGGACTTGCGTAGCCCACCCAGCAACC
ATTTCGAGCGCTTGCAGGGGAGCCTGCGGGCATACCACTCGATCCGGGTGAATCGCCAATGGCGCCTGGTCTTTCATTGG
GATGGCGAAAAAGGCGAAGCCTCGGACGTCTACCTCGACAACCATTCGTACCGATGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10528.99 Da        Isoelectric Point: 5.6254

>AT195177 WP_042716098.1 NZ_CP071063:c3870057-3869791 [Enterobacter mori]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT195177 NZ_CP094343:c3811846-3811538 [Pseudomonas sp. M1]
GTGATCATCACCGAACGCAAGCCAGTCAGCGTCGGCGAGGTGCTCAGCAGCGAGTTCCTCGATCCGCTAGGCCTGACCCA
AGGCCGCCTCGCCGAAGCGATGGGGGTGCAGCGCAAGCTGGTCAACGAACTGTGCAACGACCGGAGGGCAGTGACGGCCG
ATACCGCCCTGATGCTGGCCCGGGTATTCGGCAACTCCGCGGAGTTCTGGCTCAACCTGCAGCGGCGCAACGACCTGTGG
GCGGCGTTGAATTCGCCAGAGCGACGTGCCCGCATAGAGCGGGCTCGGCCATTGAATCGGGCGGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References