Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 535018..535693 Replicon chromosome
Accession NZ_CP071063
Organism Enterobacter mori strain 08-091

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag JY395_RS02560 Protein ID WP_215230570.1
Coordinates 535373..535693 (+) Length 107 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag JY395_RS02555 Protein ID WP_215230569.1
Coordinates 535018..535341 (+) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JY395_RS02535 (JY395_02525) 531294..533000 + 1707 WP_215230565.1 50S ribosome-binding GTPase -
JY395_RS02540 (JY395_02530) 533446..534264 + 819 WP_215230566.1 DUF932 domain-containing protein -
JY395_RS02545 (JY395_02535) 534297..534767 + 471 WP_215230567.1 DNA repair protein RadC -
JY395_RS02550 (JY395_02540) 534776..534997 + 222 WP_215230568.1 DUF987 family protein -
JY395_RS02555 (JY395_02545) 535018..535341 + 324 WP_215230569.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
JY395_RS02560 (JY395_02550) 535373..535693 + 321 WP_215230570.1 TA system toxin CbtA family protein Toxin
JY395_RS02565 (JY395_02555) 535807..536172 + 366 WP_215230571.1 DUF4942 domain-containing protein -
JY395_RS02570 (JY395_02560) 536396..537265 - 870 WP_163281774.1 HNH endonuclease -
JY395_RS02575 (JY395_02565) 537565..538032 + 468 WP_215230572.1 SymE family type I addiction module toxin -
JY395_RS02580 (JY395_02570) 538201..538464 + 264 WP_215230573.1 hypothetical protein -
JY395_RS02585 (JY395_02575) 539824..540324 + 501 WP_045292251.1 type VI secretion system contractile sheath small subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(12-105)

Antitoxin

Antitoxin CbeA

(4-102)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12071.69 Da        Isoelectric Point: 5.4732

>T195166 WP_215230570.1 NZ_CP071063:535373-535693 [Enterobacter mori]
MHISSVPVTVPVSSRLSPVQVWQQLLTYLLEHHYGLTLNDTPFHDDTAIEEHIDAGVTLADAVNFLVERYELVRIDRKGF
TWQEQTPFLTATDILRARRATGLINT

Download         Length: 321 bp

>T195166 NZ_CP094339:c4353738-4353361 [Escherichia coli]
ATGAACACATTACCCGATACACACATACGGGAGGCATCGCATTGCCAGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCGACTGCTGGACCAGCATTACGGCCTCACACTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTTGAAAAATACGCACTGGTGCGTACCGACCAGCCGGGATTC
AGCGCCTGTACTCGTTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCCCGCCGGGCAACCGGCCTGATGGCCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAACATCCGGGGGCGAAACAATGA

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 11964.68 Da        Isoelectric Point: 6.6250

>AT195166 WP_215230569.1 NZ_CP071063:535018-535341 [Enterobacter mori]
MQNSWGLKRDISPCFGARLVQEGCRLHFLADRAGISGAFNEEEALRLDQAFPLVMKQLELMLTTGELNPRHQHCVTLYHN
GLTCEADTLGSHGYVYIVIYPQASATK

Download         Length: 324 bp

>AT195166 NZ_CP094339:c4354196-4353828 [Escherichia coli]
GTGTCAGACACTCTCCCCGGGACAACGCATCCCGACGATAACAACGACCGCCCCTGGTGGGGGCTACCCTGCACCGTGAC
GCCCTGTTTTGGGGCACGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCAGACCGCGCCGGTATCAGAGGCCGGT
TCAGCGACGCGGATGCGTACCATCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCAAAAAGGCTGACCTGCGAAGCCGACACCCTCGGCAGTTG
TGGCTACGTTTATATGGCTGTTTATCCGACGCCCGAAACGAAAAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References