Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 734224..734902 Replicon chromosome
Accession NZ_CP071062
Organism Dickeya solani strain IPO2019

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag JYR06_RS03455 Protein ID WP_023637601.1
Coordinates 734471..734902 (+) Length 144 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A2K8QSU7
Locus tag JYR06_RS03450 Protein ID WP_023637600.1
Coordinates 734224..734490 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JYR06_RS03430 730674..731324 + 651 WP_022632163.1 LysE family translocator -
JYR06_RS03435 731395..732003 - 609 WP_022632164.1 HD domain-containing protein -
JYR06_RS03440 732213..732863 + 651 WP_022632165.1 hemolysin III family protein -
JYR06_RS03445 732937..733917 - 981 WP_022632166.1 tRNA-modifying protein YgfZ -
JYR06_RS03450 734224..734490 + 267 WP_023637600.1 FAD assembly factor SdhE Antitoxin
JYR06_RS03455 734471..734902 + 432 WP_023637601.1 protein YgfX Toxin
JYR06_RS03460 735002..735520 - 519 WP_022632169.1 flavodoxin FldB -
JYR06_RS03465 735649..736974 - 1326 WP_022632170.1 MHS family MFS transporter -
JYR06_RS03470 737237..738136 + 900 WP_022632171.1 site-specific tyrosine recombinase XerD -
JYR06_RS03475 738226..738933 + 708 WP_022632172.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 144 a.a.        Molecular weight: 16808.51 Da        Isoelectric Point: 11.7737

>T195147 WP_023637601.1 NZ_CP071062:734471-734902 [Dickeya solani]
VAQWQCDLRVSWRMQLFSLLTHGFLVLMILLAPWPDGYAPLWLGLVTLVVFGFVRSQRIIKSRQGEISLHGENQLHWQQR
DWQIARRPWVMRNGVLLSLRATTGKGHQRLWLASDSMGNEEWRLLRQLLQQHPLQGTESSRHH

Download         Length: 432 bp

>T195147 NZ_CP094339:178572-178679 [Escherichia coli]
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAATAAGCGGAAGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10544.03 Da        Isoelectric Point: 5.5535

>AT195147 WP_023637600.1 NZ_CP071062:734224-734490 [Dickeya solani]
MDINNKSRIHWACRRGMRELDISIMPFFEHEYDTLSDDDKQHFIRLLQCDDPDLFNWLMNHGEPVDPELKRMVSLIQTRN
KDRGPVAM

Download         Length: 267 bp

>AT195147 NZ_CP094339:c178515-178458 [Escherichia coli]
TCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2K8QSU7

References