Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 901305..902868 Replicon chromosome
Accession NZ_CP071057
Organism Marinicauda algicola strain RMAR8-3

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag JW792_RS04470 Protein ID WP_135996988.1
Coordinates 901305..902159 (-) Length 285 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag JW792_RS04475 Protein ID WP_206340898.1
Coordinates 902152..902868 (-) Length 239 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JW792_RS04440 897326..897574 + 249 WP_135997623.1 multicopper oxidase domain-containing protein -
JW792_RS04445 897663..898166 - 504 WP_084391394.1 signal peptidase II -
JW792_RS04450 898163..898822 - 660 WP_084391393.1 cation diffusion facilitator family transporter -
JW792_RS04455 898960..899370 + 411 WP_084391392.1 helix-turn-helix domain-containing protein -
JW792_RS04460 899434..900327 - 894 WP_135997627.1 IS481 family transposase -
JW792_RS04465 900438..901163 + 726 WP_135996990.1 hypothetical protein -
JW792_RS04470 901305..902159 - 855 WP_135996988.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
JW792_RS04475 902152..902868 - 717 WP_206340898.1 AbiEi antitoxin N-terminal domain-containing protein Antitoxin
JW792_RS04480 903095..904519 + 1425 WP_135996986.1 serine hydrolase -
JW792_RS04485 904565..904765 + 201 WP_135996984.1 SlyX family protein -
JW792_RS04490 904762..905796 - 1035 WP_192900991.1 acyl-CoA desaturase -
JW792_RS04495 905793..906110 - 318 WP_135996982.1 metalloregulator ArsR/SmtB family transcription factor -
JW792_RS04500 906522..907106 + 585 WP_135996981.1 NnrU family protein -
JW792_RS04505 907168..907557 + 390 WP_135996979.1 phage shock protein B -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(38-258)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(43-87)


Sequences

Toxin        


Download         Length: 285 a.a.        Molecular weight: 31235.68 Da        Isoelectric Point: 4.8272

>T195143 WP_135996988.1 NZ_CP071057:c902159-901305 [Marinicauda algicola]
MAKSPTNIATSVRQRLLNLARSEGRDFQTLLVAFGLERLIFRLSKSPHRDKFVLKGGMLVTLWTTDPGRFTRDIDFLAFG
ETGDAALTTIFAEILALDAGDGLEFSIDTITTTDIREDQVYGGKRLRTVAHLGKTEIPITIDLGFGDALPDPHYEIEYGS
ILDFEAARIRAYSPATVIAEKFQAVVALGLINGRMKDFYDLWAIPKATEIDPADLRAAIAATFERRNTPVPTEAPQGLSV
AFAEDAAKARQWLTYAEGTELKGVPLGTVLADIWTYLRAALDIN

Download         Length: 855 bp

>T195143 NZ_CP094333:c32890-32738 [Salmonella enterica subsp. enterica]
ATGCCACAGCGAACGTTTTTAATGATGTTAATCGTCATCTGTGTGACGATTCTGTGTTTTGTCTGGATGGTGAGGGATTC
GCTTTGCGTACTCCGGCTCCAGCAGGGAAACACAGTGCTTGTGGCAACGTTAGCCTACGAAGTTAAACGTTAA

Antitoxin


Download         Length: 239 a.a.        Molecular weight: 26119.16 Da        Isoelectric Point: 10.0956

>AT195143 WP_206340898.1 NZ_CP071057:c902868-902152 [Marinicauda algicola]
MAGLLLSPARRMPINVLHNLGQKCILSENMKHASSHPVTQQDRLLAYLRDHDIARAFELREIGVSATAISRAVEAGNVVR
IGRGLYQAADAEADLNTNLAEVAKRAPRSVICLLSALAFHGLTDQLPRKVWFAIGAKDWEPSIAYPPVRVVRFREPYFSD
GIETHRIGGTQVRIYSVPKSIADAFRNPKLVDRSVAIEALKAALDQRKATPAVLMQAAADYGAARIMRPYLEALTSNG

Download         Length: 717 bp

>AT195143 NZ_CP094333:32940-33002 [Salmonella enterica subsp. enterica]
TCGAAGCATTACAGTAGAGCCCTTGGTTGATTGATAAAAAAATCTCCAGGGGCTTTCTGCTGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References