Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 5332673..5333313 Replicon chromosome
Accession NZ_CP071007
Organism Pseudomonas sp. SORT22

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JYG36_RS24465 Protein ID WP_213602580.1
Coordinates 5332903..5333313 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JYG36_RS24460 Protein ID WP_093387177.1
Coordinates 5332673..5332903 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JYG36_RS24440 (JYG36_24440) 5328118..5329452 - 1335 WP_283817167.1 precorrin-3B synthase -
JYG36_RS24445 (JYG36_24445) 5329569..5330780 + 1212 WP_195885584.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE -
JYG36_RS24450 (JYG36_24450) 5330773..5331870 + 1098 WP_213602575.1 cobalt-precorrin-5B (C(1))-methyltransferase -
JYG36_RS24455 (JYG36_24455) 5331867..5332580 + 714 WP_213602578.1 cobalt-precorrin-6A reductase -
JYG36_RS24460 (JYG36_24460) 5332673..5332903 + 231 WP_093387177.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
JYG36_RS24465 (JYG36_24465) 5332903..5333313 + 411 WP_213602580.1 tRNA(fMet)-specific endonuclease VapC Toxin
JYG36_RS24470 (JYG36_24470) 5333373..5333810 + 438 WP_045196974.1 NfeD family protein -
JYG36_RS24475 (JYG36_24475) 5333834..5334691 + 858 WP_045196972.1 SPFH domain-containing protein -
JYG36_RS24480 (JYG36_24480) 5334788..5335180 + 393 WP_045196971.1 DUF2946 domain-containing protein -
JYG36_RS24485 (JYG36_24485) 5335228..5335701 + 474 WP_045196966.1 copper chaperone PCu(A)C -
JYG36_RS24490 (JYG36_24490) 5335805..5336149 + 345 WP_230090918.1 DUF2946 domain-containing protein -
JYG36_RS24495 (JYG36_24495) 5336228..5338294 + 2067 WP_213602581.1 TonB-dependent copper receptor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(7-52)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15173.57 Da        Isoelectric Point: 7.8763

>T194969 WP_213602580.1 NZ_CP071007:5332903-5333313 [Pseudomonas sp. SORT22]
MLKYMLDTNICIFTLKNKPLVVREAFNRHYGQLCISTVTLMELMYGAEKSAAPERNLAVVEGFAARLEVLSYDDRAAAHS
GQLRAELARAGTPIGPYDQMIAGHARSLGLLLVTNNIREFQRVPGLRVEDWLNPAQ

Download         Length: 411 bp

>T194969 NZ_CP094240:3772560-3772736 [Comamonas sp. 7D-2evo2]
ATGAAGCAAAGCGAGTTCCAGAGATGGCTCGCTGCGCAGGGAGCAACTTTCAGCCACGGCACACGCCACTTGAAGGTTTT
CCTGAACGGCAAGCAAACAATAATGCCCCGGCACCCAAGCCAAGAGATTGGCGAAGGACTCAGAAAAGCGATTCTGAAAC
AGCTAGGACTTAAATAG

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8583.48 Da        Isoelectric Point: 4.3322

>AT194969 WP_093387177.1 NZ_CP071007:5332673-5332903 [Pseudomonas sp. SORT22]
MEQGAVFKSNRSQAVRLPKSVALPEDVKRVDIVAVGRTRIISPSGEAWDSWFEGQDVSPDFMAEREQDTDQEREGF

Download         Length: 231 bp

>AT194969 NZ_CP094240:3772801-3773238 [Comamonas sp. 7D-2evo2]
ATGCGATTTCCTGCAAACATCGAGCCCGATGGTGATGGCTTCATGGTCTCGTTTCCCGATATCCCGGAGGCATTGACCTG
CGGCGATACCTACGATGAGGCCGTATCCATGGCCCATGATGCGCTACTGACTGCGATGGACTTCTATTTTGACGATCGCC
GCGCCGTCCCTGAGCCATCCAAGGCCGCCAAGGGCCAGGTGCTTATCTCTTTGCCGGCCAGCGTGTCGGCAAAGGTGCTG
CTGCTCAACGAGATGGTGCATCAAGGCGTGCGCCCCATCGACCTGGCAGCACGCATGGGCACGACTAAACAAGAAGTCAA
CCGGCTGACGGACCTCAAGCATGCAACCAAGATCGACACCATCGCCAAAGCCCTGGCGACCATGGGCCTTGATCTGGAGC
TAGGCGTGCGCCGCTCAGCTACTGCAGCCGCTCGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References