Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 5023882..5024401 Replicon chromosome
Accession NZ_CP070982
Organism Pseudomonas entomophila strain Small

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag JYG34_RS21965 Protein ID WP_213658317.1
Coordinates 5024111..5024401 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JYG34_RS21960 Protein ID WP_213658316.1
Coordinates 5023882..5024121 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JYG34_RS21945 (JYG34_21945) 5019005..5019529 - 525 WP_213658313.1 histidine phosphatase family protein -
JYG34_RS21950 (JYG34_21950) 5019693..5021981 - 2289 WP_213658314.1 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase -
JYG34_RS21955 (JYG34_21955) 5022303..5023790 + 1488 WP_213658315.1 methylenetetrahydrofolate reductase C-terminal domain-containing protein -
JYG34_RS21960 (JYG34_21960) 5023882..5024121 + 240 WP_213658316.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
JYG34_RS21965 (JYG34_21965) 5024111..5024401 + 291 WP_213658317.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JYG34_RS21970 (JYG34_21970) 5024404..5025177 - 774 WP_213658318.1 carbon-nitrogen hydrolase family protein -
JYG34_RS21975 (JYG34_21975) 5025413..5026453 + 1041 WP_213658319.1 DMT family transporter -
JYG34_RS21980 (JYG34_21980) 5026598..5026993 + 396 WP_213658320.1 hypothetical protein -
JYG34_RS21985 (JYG34_21985) 5027019..5027504 - 486 WP_213658321.1 PIN domain-containing protein -
JYG34_RS21990 (JYG34_21990) 5027485..5028552 - 1068 WP_213658322.1 XRE family transcriptional regulator -
JYG34_RS21995 (JYG34_21995) 5028755..5029351 + 597 WP_213658323.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-81)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-64)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11345.25 Da        Isoelectric Point: 10.3672

>T194909 WP_213658317.1 NZ_CP070982:5024111-5024401 [Pseudomonas entomophila]
MTYNLDFDARALKEWQKLGDTIRQQLKKKLATVLLNPRVEANRLHGFADCYKIKLRSSGYRMIYQVIDQEVVVFVIAVDK
RERDQVYRKAAERLAK

Download         Length: 291 bp

>T194909 NZ_CP094178:18330-19091 [Helicobacter pylori]
ATGGAAACTAAAGAAGAAGATAAAGATAAAAAGCTAGAAAAAATTATTGTATTGCTGTGCGAAGAGGGGGATTTGTCTAG
CCAAAAAGATCAAATCATCAAAGATCTCAAAGAAATCTATAAAGGAGAATACAAGCATAAATACTCAAAAATCACAACTA
TTATTTTAAATTCCACAAGGGATAAAGAGCAAGCCTTTATGATGCTCACACAAAATATAAAGACGCTCAAAGAGATTCAA
GATAATAAAGAAGTTGAAAGCATTAAACCAAAACTAGAAAAGCTTTATGATCACATGAATTTAGAGTGTATCAGACTGCA
AGATTTTGATGAGAAAATGAGTAGAGTTAAAGATATTTCTATAAGGTTAGATAATCTAAATAAAAACTATAAAAAATTAA
GCGAAGAATTGAATAAGCAGCAAACGCAATACATAACAATTTTAGGTATTTTTGCCTCTATTGTTTTAACATTTGTTGGG
GGATTGGCGTTTTCCACTTCTGTTTTATCAAATATTGACAAAGCGAACGCCTATCGTTTGGTTTTTGTTATGGCTTTTAT
AGCTTTATTTTTTGGGAATATTTTGTATCTGCTTTTTTCTTTTTTATCAAAAATATCCTTATCAAAAGAGAAAAAAGATA
AACAAGAAAATTTTTTCAAAAAACCTATTTTTTGGTTTAATCTAATGGTTACAATCCTATTTGTGATTGGTTTTGTGGGA
GAATTGCATATAATACAAAGATTAGCTTCTAAATATTTTTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9062.50 Da        Isoelectric Point: 4.8279

>AT194909 WP_213658316.1 NZ_CP070982:5023882-5024121 [Pseudomonas entomophila]
MASINVRIDDELKVRAYRELEKLGVTPSELMRQALQYVAERGQLPFKPVLLTEEDEALLATVRERLAAPQRIRVTLDDL

Download         Length: 240 bp

>AT194909 NZ_CP094178:17903-18340 [Helicobacter pylori]
ATGGTCAATGCTTTGGAACTAGCAAAATATATTCTTAAGCGTTCAAACAAAGAATTGAGCAACTTAGAATTGCAAAAAAC
TTTGTATTTCACAGAGCTTGACTATATCAAAAAGTTTGACAAACACCTAGTTTCTGATGATTTTGAAGCTTGGAAATATG
GGCCTGTTGCAAGGGAAGTGTATTATGAATATCGCAATTATGGTGCCAATTCCATTGACAAACCCAAAGAAGAAACGCTC
TCACAAAATCTTAGAAAAGATGAATTGGAAACCATCAACTACTCCATAGAAAAATGCAACGAAAAATCCTATTGGGATTT
AGTGAAAGAGAGTCATAAAGAAGATGGTGCTTGGCATAAAAGCTTCAAAGAAGATAGAAAAGAAGTCATTAGCAAAGATT
TGATCAAACAAGAAGCAAAACAAGCAAATGGAAACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References