Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-DUF971
Location 4336856..4337456 Replicon chromosome
Accession NZ_CP070982
Organism Pseudomonas entomophila strain Small

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag JYG34_RS18805 Protein ID WP_213657818.1
Coordinates 4336856..4337158 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag JYG34_RS18810 Protein ID WP_011535020.1
Coordinates 4337151..4337456 (+) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JYG34_RS18790 (JYG34_18790) 4332900..4334279 + 1380 WP_213657815.1 sodium:solute symporter -
JYG34_RS26475 4334359..4334487 - 129 WP_256660254.1 PA1414 family protein -
JYG34_RS18795 (JYG34_18795) 4334612..4335505 - 894 WP_213657816.1 LysR family transcriptional regulator -
JYG34_RS18800 (JYG34_18800) 4335612..4336778 + 1167 WP_213657817.1 MFS transporter -
JYG34_RS18805 (JYG34_18805) 4336856..4337158 + 303 WP_213657818.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JYG34_RS18810 (JYG34_18810) 4337151..4337456 + 306 WP_011535020.1 putative addiction module antidote protein Antitoxin
JYG34_RS18815 (JYG34_18815) 4337530..4338456 - 927 WP_011535021.1 DMT family transporter -
JYG34_RS18820 (JYG34_18820) 4338791..4339219 + 429 WP_249746181.1 barstar family protein -
JYG34_RS18825 (JYG34_18825) 4339309..4340456 + 1148 Protein_3692 IS3 family transposase -
JYG34_RS18830 (JYG34_18830) 4340556..4341803 + 1248 WP_213657248.1 IS256 family transposase -
JYG34_RS18835 (JYG34_18835) 4341973..4342320 - 348 WP_213657819.1 immunity 8 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 4328153..4372118 43965


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-95)

Antitoxin

Uncharacterized protein HI1420

(6-93)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11316.98 Da        Isoelectric Point: 10.6106

>T194907 WP_213657818.1 NZ_CP070982:4336856-4337158 [Pseudomonas entomophila]
MKTIESSSFRRWLIGLRDTTARARIVARTNRLKEGLAGDVSPVGHGMSELRVHYGPGYRVYFHQCGDTLIILLCGGDKGS
QQRDIKAARQILQSWRMQND

Download         Length: 303 bp

>T194907 NZ_CP094175:576261-576527 [Helicobacter pylori]
GTGTTGAAACTCAACCTTAAAAAATCTTTTCAAAAAGATTTTGATAAATTACTTTTGAATGGGTTTGATGATAGCGTTTT
GAATGCAGTCATTCTGTCTTTGAGAAAAAAAGAACCGCTAGACCCACAATTTAAAGATCACGCTTTAAAAGGCAATTGGA
AGCCTTTTAGAGAATGCCACATTAAATCTGATATTTTGCTTGTGTATTTAGTGAAAGGTGATGAGCTTATTTTAGTAAGG
CTAGGCAGTCATAGCGAGCTGTTTTAA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10851.36 Da        Isoelectric Point: 5.5900

>AT194907 WP_011535020.1 NZ_CP070982:4337151-4337456 [Pseudomonas entomophila]
MTETFHEFDAAAYLTSPEAIAQFMTDALETGDAAYVAKAVGVVARAKGMSELAKETGLSREQLYRSFSEHGNPTLKSFLT
VMKALGIDMAARPHLVQQGVG

Download         Length: 306 bp

>AT194907 NZ_CP094175:575903-576280 [Helicobacter pylori]
ATGCCTAATTCTCCCACCAAAAAAGACTACACACAATACAGCGAAAAACAGCTTTTTAACTTAATCAACCAATTAGAACA
AAAAATCAAAAAGATGCAAAATGATAGAGCTTCTTTTAAAGAAAAAATGGCTAAAGAATTGGAAAAAAGGGATCAAAACT
TTAAGGATAAAATAGACGCATTAAATGAACTCTTGCAAAAAATCAGCCAAGCTTTTGATAATAAAAGAGATTGTTGTTTG
GGGCATGAAACCCCAAACCTTGAAACGCAACAAGCCATGAGAGATGCACTTAACAAAGAAACCGATTTGATTGTTGAGGA
TTTTTCTAGTTATAGCGATGAAAGAAAAAAGGCGTTAGGTGTTGAAACTCAACCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References