194906

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 3949280..3950319 Replicon chromosome
Accession NZ_CP070982
Organism Pseudomonas entomophila strain Small

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag JYG34_RS17085 Protein ID WP_213657553.1
Coordinates 3949744..3950319 (+) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag JYG34_RS17080 Protein ID WP_213657552.1
Coordinates 3949280..3949747 (+) Length 156 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JYG34_RS17060 (JYG34_17060) 3944920..3947073 + 2154 WP_213657550.1 ATP-binding domain-containing protein -
JYG34_RS17065 (JYG34_17065) 3947066..3947767 + 702 WP_213657551.1 DUF2290 domain-containing protein -
JYG34_RS17070 (JYG34_17070) 3948170..3948415 + 246 WP_011534689.1 hypothetical protein -
JYG34_RS17075 (JYG34_17075) 3948564..3948833 + 270 WP_011534690.1 DUF3077 domain-containing protein -
JYG34_RS17080 (JYG34_17080) 3949280..3949747 + 468 WP_213657552.1 helix-turn-helix domain-containing protein Antitoxin
JYG34_RS17085 (JYG34_17085) 3949744..3950319 + 576 WP_213657553.1 PIN domain-containing protein Toxin
JYG34_RS17090 (JYG34_17090) 3950459..3951622 - 1164 WP_213657554.1 ATP-binding protein -
JYG34_RS17095 (JYG34_17095) 3951705..3953021 - 1317 WP_213657555.1 APC family permease -
JYG34_RS17100 (JYG34_17100) 3953303..3954115 - 813 WP_213657556.1 LuxR C-terminal-related transcriptional regulator -
JYG34_RS17105 (JYG34_17105) 3954238..3955053 + 816 WP_213657557.1 carbon-nitrogen hydrolase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(9-115)

Antitoxin

SinI-like, DNA-binding domain

(84-129)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21558.70 Da        Isoelectric Point: 4.7497

>T194906 WP_213657553.1 NZ_CP070982:3949744-3950319 [Pseudomonas entomophila]
MKHSSFTALYDANVLYPAILRDLLMNLALTGVYRARWSARIHDEWKRNLLLNRPDLTQEQLDRTSGLMDAAVPDALVSDY
EALVSGLDLPDEDDRHVLAAAIKGNASVIVTFNLKDFPDTALRGFDIEALHPDDFIADLWDLDKAAVLEAVQRQRQSLKD
PPQSVQMYLDKLLQQKLPEAVKLLSGFKFLL

Download         Length: 576 bp

>T194906 NZ_CP094175:20461-21240 [Helicobacter pylori]
ATGGAAACTAAAGAAGAGGATAAAGATAAAAAGCTAGAAGAAATTATTGTATTGCTGTGCGAAGAGGGGGATTTGTCTAG
TCAAAAAGATCAAATCATCAAAGATCTCAAAGAAATCTATGAAGGAGAATACAAGCATAAATACTCAAAAATCACAACTA
TTATTTTAAATTCCATAAGGGATAAAGAGCAAGCCTTTATGATGCTCACACAAAATATAAAGACACTCAAAGAGATTCAA
GATAACAAAGAAGTTGAAAGCATTAAACCAAAATTAGAAAAGCTTTATGATCACATGAATTTAGAGTGTATTAGACTGCA
AGATTTTGATGAGAAAATGAGTAGAGTTAAAGATATTTCTATAAAGTTAGATAATCTAAATAAAAACTATAAAAAATTAA
GCGAAGAATTGAATAAGCAACAAACACAATACATAACAATTTTAGGTATTTTTGTCTCTATTGTTTTAACATTTGTTGGG
GGATTGGCGTTTTCCACTTCTGTTTTATCAAATATTGACAAAGCGAACGCCTATCGTTTGGTTTTTGTTATGGCTTTTAT
AGCTTTATTTTTTGGGAATATTTTGTATCTGCTTTTTTCTTTTTTATCAAAAATATCCTTATCATCAAAAATATCCTTAT
CAGAAGAGGAAAAAGATAAACAAGAAAATTTTTTCAAAAAACCTATTTTTTGGTTTAATCTAATGGTTACAATTCTATTT
GTGATTGGTTTTTTTGGAGAATTGCATATAATACAAAGATTAGTTTCTAAATATCTTTGA

Antitoxin


Download         Length: 156 a.a.        Molecular weight: 17121.49 Da        Isoelectric Point: 5.9259

>AT194906 WP_213657552.1 NZ_CP070982:3949280-3949747 [Pseudomonas entomophila]
MTTADLSHKLLPDEHEIAAAVESSRTLAAFLSTASQTQRIELLNEDNQRQVVEVPTFALRLFGEILSELALGNAVKVVPI
HAELTTQEAADLLNVSRPHLVKLLDDGLIPHTKTGRHRRVKFADLVGYKDKRDEASRAAMDELAAQAQALRMGYE

Download         Length: 468 bp

>AT194906 NZ_CP094175:20034-20471 [Helicobacter pylori]
ATGGTCAATACTTTGGAATTAGCAAAATATATTCTTAAGCATTCCAACAAAGAATTGAGCAACTTAGAATTGCAAAAAAC
TTTGTATTTCACAGAACTTGACTATATTAAAAAGTTTGACAAACACCTAGTTTCTGATGATTTTGAAGCTTGGAAATATG
GGCCTGTTGCAAGAGAAGTGTATTATGAATATCGCAATTATGGTGCCAGTTCTATTGACAAACCCAAAGAAGAAACGCTC
TCACAAAGTCTTAGAGAAGATGAACTTGAAACCATCAATCGCTCCATAGAAAAATGCAACGAAAAATCCTATTGGGATTT
AGTGAAAGAGAGTCATAAAGAAGATGGCGCTTGGCATAAAAGCTTCAAAGAAGATAGAAAAGAAATCATTAGCAAAGATT
TGATCAAACAAGAAGCAAAACAAGCAAATGGAAACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References