Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | hicAB/HicA-HicB |
| Location | 744318..744964 | Replicon | chromosome |
| Accession | NZ_CP070982 | ||
| Organism | Pseudomonas entomophila strain Small | ||
Toxin (Protein)
| Gene name | hicA | Uniprot ID | - |
| Locus tag | JYG34_RS03305 | Protein ID | WP_213659467.1 |
| Coordinates | 744318..744500 (+) | Length | 61 a.a. |
Antitoxin (Protein)
| Gene name | hicB | Uniprot ID | - |
| Locus tag | JYG34_RS03310 | Protein ID | WP_213659468.1 |
| Coordinates | 744557..744964 (+) | Length | 136 a.a. |
Genomic Context
Location: 744318..744500 (183 bp)
Type: Toxin
Protein ID: WP_213659467.1
Type: Toxin
Protein ID: WP_213659467.1
Location: 744557..744964 (408 bp)
Type: Antitoxin
Protein ID: WP_213659468.1
Type: Antitoxin
Protein ID: WP_213659468.1
Location: 745519..746106 (588 bp)
Type: Others
Protein ID: WP_213659470.1
Type: Others
Protein ID: WP_213659470.1
Location: 746294..747190 (897 bp)
Type: Others
Protein ID: WP_213659471.1
Type: Others
Protein ID: WP_213659471.1
Location: 747310..748977 (1668 bp)
Type: Others
Protein ID: WP_213659472.1
Type: Others
Protein ID: WP_213659472.1
Location: 739338..739961 (624 bp)
Type: Others
Protein ID: WP_213659462.1
Type: Others
Protein ID: WP_213659462.1
Location: 739972..740391 (420 bp)
Type: Others
Protein ID: WP_213659463.1
Type: Others
Protein ID: WP_213659463.1
Location: 740388..741713 (1326 bp)
Type: Others
Protein ID: WP_213659464.1
Type: Others
Protein ID: WP_213659464.1
Location: 741713..743467 (1755 bp)
Type: Others
Protein ID: WP_213659465.1
Type: Others
Protein ID: WP_213659465.1
Location: 743498..744103 (606 bp)
Type: Others
Protein ID: WP_213659466.1
Type: Others
Protein ID: WP_213659466.1
Location: 745005..745319 (315 bp)
Type: Others
Protein ID: WP_213659469.1
Type: Others
Protein ID: WP_213659469.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JYG34_RS03280 (JYG34_03280) | 739338..739961 | - | 624 | WP_213659462.1 | lysophospholipid acyltransferase family protein | - |
| JYG34_RS03285 (JYG34_03285) | 739972..740391 | - | 420 | WP_213659463.1 | hypothetical protein | - |
| JYG34_RS03290 (JYG34_03290) | 740388..741713 | - | 1326 | WP_213659464.1 | phosphatase PAP2/dual specificity phosphatase family protein | - |
| JYG34_RS03295 (JYG34_03295) | 741713..743467 | - | 1755 | WP_213659465.1 | bifunctional alpha/beta hydrolase/class I SAM-dependent methyltransferase | - |
| JYG34_RS03300 (JYG34_03300) | 743498..744103 | - | 606 | WP_213659466.1 | CDP-alcohol phosphatidyltransferase family protein | - |
| JYG34_RS03305 (JYG34_03305) | 744318..744500 | + | 183 | WP_213659467.1 | type II toxin-antitoxin system HicA family toxin | Toxin |
| JYG34_RS03310 (JYG34_03310) | 744557..744964 | + | 408 | WP_213659468.1 | type II toxin-antitoxin system HicB family antitoxin | Antitoxin |
| JYG34_RS03315 (JYG34_03315) | 745005..745319 | - | 315 | WP_213659469.1 | putative quinol monooxygenase | - |
| JYG34_RS03320 (JYG34_03320) | 745519..746106 | + | 588 | WP_213659470.1 | NAD(P)H-dependent oxidoreductase | - |
| JYG34_RS03325 (JYG34_03325) | 746294..747190 | + | 897 | WP_213659471.1 | LysR family transcriptional regulator | - |
| JYG34_RS03330 (JYG34_03330) | 747310..748977 | + | 1668 | WP_213659472.1 | gamma-glutamyltransferase | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 61 a.a. Molecular weight: 6926.98 Da Isoelectric Point: 11.2510
>T194905 WP_213659467.1 NZ_CP070982:744318-744500 [Pseudomonas entomophila]
MRSRDVIQLIEADGWYEVEVKGSHHQFRHPFKRGRVTVPHPKSDLPRGTAHSILKRAGLK
MRSRDVIQLIEADGWYEVEVKGSHHQFRHPFKRGRVTVPHPKSDLPRGTAHSILKRAGLK
Download Length: 183 bp
>T194905 NZ_CP094173:1617045-1617326 [Helicobacter pylori]
ATGCTTAAAGTCAGAACTAAGAAAGATTTTCTTAAAGACTTTAATAAGCATATCTTATCTGGGCGTATTAAAGAAAGCGA
TGTTACAAGCATTGTTGATTGCCTCAAAGAGCAAAAACCACTCCAACAAAAGTATTGCGACCATGCCTTGAGTGGCAATC
TTAAAGGGTTGAGAGAGTGTCATGTCAAGCCAAACTTGTTATTGATTTATGAAATCAAAAAACAAGAAAACGAACTTGTT
TTATTGCGTCTAGACACTCATAGCGAGCTATTTAAAAAGTGA
ATGCTTAAAGTCAGAACTAAGAAAGATTTTCTTAAAGACTTTAATAAGCATATCTTATCTGGGCGTATTAAAGAAAGCGA
TGTTACAAGCATTGTTGATTGCCTCAAAGAGCAAAAACCACTCCAACAAAAGTATTGCGACCATGCCTTGAGTGGCAATC
TTAAAGGGTTGAGAGAGTGTCATGTCAAGCCAAACTTGTTATTGATTTATGAAATCAAAAAACAAGAAAACGAACTTGTT
TTATTGCGTCTAGACACTCATAGCGAGCTATTTAAAAAGTGA
Antitoxin
Download Length: 136 a.a. Molecular weight: 14646.54 Da Isoelectric Point: 4.7269
>AT194905 WP_213659468.1 NZ_CP070982:744557-744964 [Pseudomonas entomophila]
MKFPVVLHKDEGSDYGVIVPDVPGCFSAGFSVSQALDNVQEALALHFEGLVADGEALPQAQEVDVHVANPDYAGGVWAVV
EFDVTPYLGKAVRFNATLPENLLQRIDEKVKRDHRYASRSGFLASAALRELAVVH
MKFPVVLHKDEGSDYGVIVPDVPGCFSAGFSVSQALDNVQEALALHFEGLVADGEALPQAQEVDVHVANPDYAGGVWAVV
EFDVTPYLGKAVRFNATLPENLLQRIDEKVKRDHRYASRSGFLASAALRELAVVH
Download Length: 408 bp
>AT194905 NZ_CP094173:1616738-1617052 [Helicobacter pylori]
ATGTCAAATATTATTACAGATTACTCGCAATACAATGAAAAGCAACTGCACAATTTCTTAAACGCCATTGAAAAACAATT
GCTTAAGGCAGAAGGGGATAAAAATAAGGCGATAAAAAAAATCCAAGAGTGTGAATTGCAAGAACAAATGATCAGACAAG
TTTTAGCCCAAAAACATTCTCAAGAAAAAGAACCCACACAAAGTTTGTTAAACACGATCGCCTCAAAAGATGACCCAGAA
TGCGATGTTTCGTTTGGAGATTTCAATGATTTTTTACAAATAGCAAAACAAGAAAGAGAAAGGCATAATGCTTAA
ATGTCAAATATTATTACAGATTACTCGCAATACAATGAAAAGCAACTGCACAATTTCTTAAACGCCATTGAAAAACAATT
GCTTAAGGCAGAAGGGGATAAAAATAAGGCGATAAAAAAAATCCAAGAGTGTGAATTGCAAGAACAAATGATCAGACAAG
TTTTAGCCCAAAAACATTCTCAAGAAAAAGAACCCACACAAAGTTTGTTAAACACGATCGCCTCAAAAGATGACCCAGAA
TGCGATGTTTCGTTTGGAGATTTCAATGATTTTTTACAAATAGCAAAACAAGAAAGAGAAAGGCATAATGCTTAA