Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 299311..301040 Replicon chromosome
Accession NZ_CP070982
Organism Pseudomonas entomophila strain Small

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag JYG34_RS01275 Protein ID WP_213659181.1
Coordinates 299311..299952 (+) Length 214 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag JYG34_RS01280 Protein ID WP_213659182.1
Coordinates 299952..301040 (+) Length 363 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JYG34_RS01255 (JYG34_01255) 295392..295907 + 516 WP_213659178.1 dihydrofolate reductase -
JYG34_RS01260 (JYG34_01260) 295948..297339 - 1392 WP_213659179.1 L-cystine transporter -
JYG34_RS01265 (JYG34_01265) 297587..298642 + 1056 WP_162042905.1 haloacid dehalogenase-like hydrolase -
JYG34_RS01270 (JYG34_01270) 298733..299314 + 582 WP_213659180.1 DarT ssDNA thymidine ADP-ribosyltransferase family protein -
JYG34_RS01275 (JYG34_01275) 299311..299952 + 642 WP_213659181.1 DUF4433 domain-containing protein Toxin
JYG34_RS01280 (JYG34_01280) 299952..301040 + 1089 WP_213659182.1 macro domain-containing protein Antitoxin
JYG34_RS01285 (JYG34_01285) 301098..302939 - 1842 WP_213659183.1 dihydroxy-acid dehydratase -
JYG34_RS01290 (JYG34_01290) 303256..304929 + 1674 WP_213659184.1 DUF4153 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(14-213)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 214 a.a.        Molecular weight: 24595.14 Da        Isoelectric Point: 9.1953

>T194904 WP_213659181.1 NZ_CP070982:299311-299952 [Pseudomonas entomophila]
MTYTRLNPSKALIWRVVHRDNLPWLLDNGLCAVSRVNLSSGYVGIGNPDLISKRSRRAVPIHPGGTLADYVPFYFTPFSV
MMKNIHSGRGVQQRRNEEIVILVSSLYHVRSLGLPFVFTDAHAYPDWAGYYSDLEHLDKIDWQILQSRDFKRDPDDPRKM
ERYQAEALIHGHVPVAGLLGIVCYNEALQRRVDQEVRQRQLDLPVHARPGWYF

Download         Length: 642 bp

>T194904 NZ_CP094173:613175-613447 [Helicobacter pylori]
ATGCTGATGATTGAAACCAGTAAAAAATTTGATAAGGATCTTAAAATTCTTGTTAAAAACGGATTTGATTTAAAGCTTTT
ATATAAAGTGGTTGAAAATTTAGCCAAAGAGCAACCCCTAGCTCCCAAATACAAAGACCACCCGCTCAAAGGCGCTTTAA
AAGATTTTAGGGAATGCCACCTAAAACCGGATTTATTGCTTGTCTATCAAATTAAAAAACAAGAAAACACCCTCTTTTTA
GTAAGGCTAGGCAGTCATAGCGAGCTGTTTTAA

Antitoxin


Download         Length: 363 a.a.        Molecular weight: 40502.41 Da        Isoelectric Point: 5.4588

>AT194904 WP_213659182.1 NZ_CP070982:299952-301040 [Pseudomonas entomophila]
MIRFTQGNLLEAKAEALVNTVNTVGVMGKGIALMFKERFVENYRLYAAACKADEVVTGKMFITEVRELDGPRWVVNFPTK
RHWRSPSQLAWITDGLHDLRSFILANDVRSIAIPPLGAGNGGLPWAAVREQIEVVLGDLDADVLVFEPTSKYQNVSKRTG
VEKLTPARALIAELVRRYWVLGMECSLLEIQKLAWFLERSIECFTPDDNPLNLQFSAHKYGPYTNRLEHLLNNLDGSYLH
CDKRIGDAGPLDVIWFDEGRKAFVDTYLQSEAKVHLPALEFTAELIDGFESPFGMELLATVDWMLHRDGVAPTVDAIREG
LQNWSGGKEAAARKNALFDDDSLATALKKLSVFQAQGVVQVH

Download         Length: 1089 bp

>AT194904 NZ_CP094173:612877-613188 [Helicobacter pylori]
ATGCCTAACACCACCGCCAAAAAAGACTACACACGATACAGCGAAAAACAGCTTTTTAACTTTTTAAATTCTATCAAGAC
CAAACAAAAAAGAGCGTTAGAAAAATTGAAAGAAATCCAAGCTCAAAAACAAAGAATCAAAAAAGCCCTCCAATTTAAAG
CGCTCCATTTAACCGAAAACGGATACACCATAGAAGAAGAGCGAGAAATCTTAGCAAGGGCTAAAGACACCAAGAACCAC
CTTTGTTTTAAAAGTGTAGAGGATTTTAAAAAGCATTGTGAAAACTTAAGATTTAAAAATGCTGATGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References