Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/upstrm_HI1419-dnstrm_HI1420 |
Location | 502025..502624 | Replicon | chromosome |
Accession | NZ_CP070981 | ||
Organism | Pseudomonas rhodesiae strain DLA23 |
Toxin (Protein)
Gene name | relE | Uniprot ID | A0A5C5P148 |
Locus tag | JYG38_RS02165 | Protein ID | WP_034095668.1 |
Coordinates | 502319..502624 (-) | Length | 102 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | A0A8I1E6D6 |
Locus tag | JYG38_RS02160 | Protein ID | WP_034095667.1 |
Coordinates | 502025..502315 (-) | Length | 97 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
JYG38_RS02140 (JYG38_02140) | 498436..500496 | - | 2061 | WP_213632964.1 | TonB-dependent copper receptor | - |
JYG38_RS02145 (JYG38_02145) | 500589..500990 | - | 402 | WP_034095664.1 | DUF2946 domain-containing protein | - |
JYG38_RS02150 (JYG38_02150) | 501002..501484 | - | 483 | WP_034136693.1 | copper chaperone PCu(A)C | - |
JYG38_RS02155 (JYG38_02155) | 501532..501927 | - | 396 | WP_094065078.1 | DUF2946 domain-containing protein | - |
JYG38_RS02160 (JYG38_02160) | 502025..502315 | - | 291 | WP_034095667.1 | putative addiction module antidote protein | Antitoxin |
JYG38_RS02165 (JYG38_02165) | 502319..502624 | - | 306 | WP_034095668.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
JYG38_RS02170 (JYG38_02170) | 503001..503735 | - | 735 | WP_213632966.1 | cobalt-precorrin-6A reductase | - |
JYG38_RS02175 (JYG38_02175) | 503732..504937 | - | 1206 | WP_213632968.1 | precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE | - |
JYG38_RS02180 (JYG38_02180) | 505033..506322 | + | 1290 | WP_276574130.1 | precorrin-3B synthase | - |
JYG38_RS02185 (JYG38_02185) | 506315..506941 | + | 627 | WP_094065075.1 | precorrin-8X methylmutase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 102 a.a. Molecular weight: 11640.25 Da Isoelectric Point: 5.8918
>T194902 WP_034095668.1 NZ_CP070981:c502624-502319 [Pseudomonas rhodesiae]
MTIEFNETIEFANWLEAVRDPFVKVRVVKRVRMAEAGNFGDCESVGDGVFEMRIHYGPGYRVYFTRRDEVVYLLLIGGDK
STQSRDIKRAKQIAINFGSEE
MTIEFNETIEFANWLEAVRDPFVKVRVVKRVRMAEAGNFGDCESVGDGVFEMRIHYGPGYRVYFTRRDEVVYLLLIGGDK
STQSRDIKRAKQIAINFGSEE
Download Length: 306 bp
>T194902 NZ_CP094171:577240-577524 [Helicobacter pylori]
ATGTATGCTTTAGCGTTTGATTTAAAGATTGAGATTTTAAAAAAAGAATACGGAGAACCCTACAATAAAGCCTATGATGA
TTTAAGGCAAGAATTAGAGCTATTAGGGTTTGAATGGACTCAAGGGAGCGTTTATGTTAATTATTCTAAAGAAAACACTC
TAGCACAAGTCTATAAAGCGATCAATAAACTCTCTCAAATTGAGTGGTTTAAAAAGTCTGTTAGGGATATTAGAGCGTTT
AAGGTAGAGGACTTTAGCGATTTTACTGAGATTGTGAAATCCTAG
ATGTATGCTTTAGCGTTTGATTTAAAGATTGAGATTTTAAAAAAAGAATACGGAGAACCCTACAATAAAGCCTATGATGA
TTTAAGGCAAGAATTAGAGCTATTAGGGTTTGAATGGACTCAAGGGAGCGTTTATGTTAATTATTCTAAAGAAAACACTC
TAGCACAAGTCTATAAAGCGATCAATAAACTCTCTCAAATTGAGTGGTTTAAAAAGTCTGTTAGGGATATTAGAGCGTTT
AAGGTAGAGGACTTTAGCGATTTTACTGAGATTGTGAAATCCTAG
Antitoxin
Download Length: 97 a.a. Molecular weight: 10404.99 Da Isoelectric Point: 5.8124
>AT194902 WP_034095667.1 NZ_CP070981:c502315-502025 [Pseudomonas rhodesiae]
MSESFSRFDAAKYLKTPLEMAAYLETCFEDDAGDGLLIRTALNDIARAQGMTQVARDAGLGRESLYKALSSSGNPEFATI
MKVMKALGLKLHATVI
MSESFSRFDAAKYLKTPLEMAAYLETCFEDDAGDGLLIRTALNDIARAQGMTQVARDAGLGRESLYKALSSSGNPEFATI
MKVMKALGLKLHATVI
Download Length: 291 bp
>AT194902 NZ_CP094171:576867-577259 [Helicobacter pylori]
ATGCCTAACTCTCCCACCAAAAAAGACTACACACGATACAGCGAAAAACAGCTTTTTAACTTAATCAATCAATTAGAGCG
AAAAATCAAAAAGATGCAAAATGATAGAGCTTCTTTTAAAGAAAAAATGGCTAAAGAATTGGAAAAAAGGGATCAAAACT
TTAAGGATAAAATAGACGCATTAAATGAACTCTTGCAAAAAATCAGCCAAGCTTTTGATAATAAAAGAGATTGTTGTTTT
GGGCATGAAACCCCAAACCTTGAAACGCAACAAGCCATGAGAGAAGCGTTAAATGGGGTTAATCTCACTCAAATTGATAG
TTTAGATGATCTTACAAACGAGTTAAAAAGAGAAAATAGTAAAGGTTTTGAAAATGTATGCTTTAGCGTTTGA
ATGCCTAACTCTCCCACCAAAAAAGACTACACACGATACAGCGAAAAACAGCTTTTTAACTTAATCAATCAATTAGAGCG
AAAAATCAAAAAGATGCAAAATGATAGAGCTTCTTTTAAAGAAAAAATGGCTAAAGAATTGGAAAAAAGGGATCAAAACT
TTAAGGATAAAATAGACGCATTAAATGAACTCTTGCAAAAAATCAGCCAAGCTTTTGATAATAAAAGAGATTGTTGTTTT
GGGCATGAAACCCCAAACCTTGAAACGCAACAAGCCATGAGAGAAGCGTTAAATGGGGTTAATCTCACTCAAATTGATAG
TTTAGATGATCTTACAAACGAGTTAAAAAGAGAAAATAGTAAAGGTTTTGAAAATGTATGCTTTAGCGTTTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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