Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | BrnTA/BrnT_toxin-BrnA |
| Location | 4369107..4369611 | Replicon | chromosome |
| Accession | NZ_CP070980 | ||
| Organism | Pseudomonas rhodesiae strain AAMF24 | ||
Toxin (Protein)
| Gene name | brnT | Uniprot ID | A0A2G0X8I2 |
| Locus tag | JYG35_RS19820 | Protein ID | WP_047881292.1 |
| Coordinates | 4369372..4369611 (-) | Length | 80 a.a. |
Antitoxin (Protein)
| Gene name | brnA | Uniprot ID | A0A2G0X8Q6 |
| Locus tag | JYG35_RS19815 | Protein ID | WP_034114783.1 |
| Coordinates | 4369107..4369355 (-) | Length | 83 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JYG35_RS19795 (JYG35_19795) | 4364901..4365704 | + | 804 | WP_213547777.1 | alpha/beta hydrolase | - |
| JYG35_RS19800 (JYG35_19800) | 4365708..4366271 | + | 564 | WP_034099645.1 | peptidylprolyl isomerase | - |
| JYG35_RS19805 (JYG35_19805) | 4366354..4368186 | + | 1833 | WP_034099647.1 | ABC transporter ATP-binding protein | - |
| JYG35_RS19810 (JYG35_19810) | 4368334..4369035 | + | 702 | WP_034099649.1 | aquaporin Z | - |
| JYG35_RS19815 (JYG35_19815) | 4369107..4369355 | - | 249 | WP_034114783.1 | BrnA antitoxin family protein | Antitoxin |
| JYG35_RS19820 (JYG35_19820) | 4369372..4369611 | - | 240 | WP_047881292.1 | BrnT family toxin | Toxin |
| JYG35_RS19825 (JYG35_19825) | 4369689..4370813 | - | 1125 | WP_047881364.1 | GNAT family N-acetyltransferase | - |
| JYG35_RS19830 (JYG35_19830) | 4371098..4372420 | + | 1323 | WP_034099652.1 | putative porin | - |
| JYG35_RS19835 (JYG35_19835) | 4372528..4372773 | - | 246 | WP_034099654.1 | zf-HC2 domain-containing protein | - |
| JYG35_RS19840 (JYG35_19840) | 4372767..4373381 | - | 615 | WP_034114785.1 | RNA polymerase sigma factor | - |
| JYG35_RS19845 (JYG35_19845) | 4373398..4374519 | - | 1122 | WP_034099658.1 | beta-ketoacyl-ACP synthase III | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 80 a.a. Molecular weight: 9353.79 Da Isoelectric Point: 7.8593
>T194901 WP_047881292.1 NZ_CP070980:c4369611-4369372 [Pseudomonas rhodesiae]
MRFEWDESKNKVNISKHGIDFNDVPDIFRHPMLALRDDRADYGEERWICIGWIKRLMGVVVYTERCGDVIRIISARKAT
MRFEWDESKNKVNISKHGIDFNDVPDIFRHPMLALRDDRADYGEERWICIGWIKRLMGVVVYTERCGDVIRIISARKAT
Download Length: 240 bp
>T194901 NZ_CP094171:18119-18883 [Helicobacter pylori]
ATGGAAACTAAAGAAGAAGATAAAGATAAAAAGCTAGAAAAAATTATTGTATTGTTGTGCGAAGAGGGGGATTTGTCTAG
TCAAAAAGATCAAATCATCAAAGATCTCAAAGAAATCTATGAAGGAGAATACAAGCATAAATACTCAAAAATCACAACTA
TTATTTTAAATTCCACAAGGGATAAAGAGCAAGCCTTTATGATGCTCACACAAAATATAAAGACACTCAAAGAGATTCAA
GATAATAAGGAAGTTGAAAGCATTAAGCCAAAACTAGAAAAGCTTTATGATCACATGAATTTAGAGTGTATCAGACTGCA
AGATTTTGATGAGAAAATGAGTAGAGTTAAAGATGTTTCTATCAGGTTAGAAGATGATCTAAATAAAAACTATAAAAAAT
TAAGCGAAGAATTGAATAAGCAGCAAACGCAATACATAACAATTTTAGGTATTTTTGCCTCTATTGTTTTAACATTTGTT
GGGGGATTGGCGTTTTCCACTTCTGTTTTATCAAATATTGACAAAGCGAACGCCTATCGTTTGGTTTTTGTTATGGCTTT
TATAGCTTTATTTTTTGGGAATATTTTGTATCTGCTTTTTTCTTTTTTATCAAAAATATCCTTATCAAAAGAGAAAAAAG
ATAAAGAAGAAAATTTTTTCAAAAAACCTATTTTTTGGTTTAATCTGATGGTTACAATCCTATTTGTGATTGGTTTTTTT
GGAGAATTGCATATAATACAAAGATTAGTTTCTAAATATCTTTGA
ATGGAAACTAAAGAAGAAGATAAAGATAAAAAGCTAGAAAAAATTATTGTATTGTTGTGCGAAGAGGGGGATTTGTCTAG
TCAAAAAGATCAAATCATCAAAGATCTCAAAGAAATCTATGAAGGAGAATACAAGCATAAATACTCAAAAATCACAACTA
TTATTTTAAATTCCACAAGGGATAAAGAGCAAGCCTTTATGATGCTCACACAAAATATAAAGACACTCAAAGAGATTCAA
GATAATAAGGAAGTTGAAAGCATTAAGCCAAAACTAGAAAAGCTTTATGATCACATGAATTTAGAGTGTATCAGACTGCA
AGATTTTGATGAGAAAATGAGTAGAGTTAAAGATGTTTCTATCAGGTTAGAAGATGATCTAAATAAAAACTATAAAAAAT
TAAGCGAAGAATTGAATAAGCAGCAAACGCAATACATAACAATTTTAGGTATTTTTGCCTCTATTGTTTTAACATTTGTT
GGGGGATTGGCGTTTTCCACTTCTGTTTTATCAAATATTGACAAAGCGAACGCCTATCGTTTGGTTTTTGTTATGGCTTT
TATAGCTTTATTTTTTGGGAATATTTTGTATCTGCTTTTTTCTTTTTTATCAAAAATATCCTTATCAAAAGAGAAAAAAG
ATAAAGAAGAAAATTTTTTCAAAAAACCTATTTTTTGGTTTAATCTGATGGTTACAATCCTATTTGTGATTGGTTTTTTT
GGAGAATTGCATATAATACAAAGATTAGTTTCTAAATATCTTTGA
Antitoxin
Download Length: 83 a.a. Molecular weight: 9642.95 Da Isoelectric Point: 7.0124
>AT194901 WP_034114783.1 NZ_CP070980:c4369355-4369107 [Pseudomonas rhodesiae]
MTQTSKTDWERLAKMKDKEIDTSDIPELDAEFFRRAELRVPVKQAVTIRLDADVLEWFKGQGTGYQTRINQLLRQYMQAH
QG
MTQTSKTDWERLAKMKDKEIDTSDIPELDAEFFRRAELRVPVKQAVTIRLDADVLEWFKGQGTGYQTRINQLLRQYMQAH
QG
Download Length: 249 bp
>AT194901 NZ_CP094171:17692-18129 [Helicobacter pylori]
ATGGTCAATGCTTTGGAACTAGCAAAATATATTCTTAAGCGTTCAAACAAAGAATTGAGCAACTTAGAATTGCAAAAAAC
TTTGTATTTCACAGAGCTTGACTATATCAAAAAGTTTGACAAACACCTAGTTTCTGATGATTTTGAAGCTTGGAAATATG
GGCCTGTTGCAAGGGAAGTGTATTATGAATATCGCAATTATGGTGCCAATTCCATTGACAAACCCAAAGAAGAAACGCTC
TCACAAAATCTTAGAAAAGATGAATTGGAAACCATCAATCGCTCCATAGAAAAATGCAACGAAAAATCCTATTGGGATTT
AGTGAAAGAGAGTCATAAAGAAGATGGTGCTTGGCATAAAAGCTTCAAAGAAGATAGAAAAGAAATCATTAGCAAAGATT
TGATCAAACAAGAAGCAAAACAAGCAAATGGAAACTAA
ATGGTCAATGCTTTGGAACTAGCAAAATATATTCTTAAGCGTTCAAACAAAGAATTGAGCAACTTAGAATTGCAAAAAAC
TTTGTATTTCACAGAGCTTGACTATATCAAAAAGTTTGACAAACACCTAGTTTCTGATGATTTTGAAGCTTGGAAATATG
GGCCTGTTGCAAGGGAAGTGTATTATGAATATCGCAATTATGGTGCCAATTCCATTGACAAACCCAAAGAAGAAACGCTC
TCACAAAATCTTAGAAAAGATGAATTGGAAACCATCAATCGCTCCATAGAAAAATGCAACGAAAAATCCTATTGGGATTT
AGTGAAAGAGAGTCATAAAGAAGATGGTGCTTGGCATAAAAGCTTCAAAGAAGATAGAAAAGAAATCATTAGCAAAGATT
TGATCAAACAAGAAGCAAAACAAGCAAATGGAAACTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A2G0X8I2 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A2G0X8Q6 |