Detailed information of TA system TA194875

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 246275..246842
• Replicon: chromosome
• Accession: NZ_CP070975
• Organism: Alcaligenes sp. SORT26

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: JYG33_RS01145
• Protein ID: WP_207873796.1
• Coordinates: 246513..246842 (+)
• Length: 110 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: JYG33_RS01140
• Protein ID: WP_207873795.1
• Coordinates: 246275..246526 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JYG33_RS01115 (JYG33_01115)	242409..242744	-	336	WP_021446816.1	flagellar protein FliT	-
JYG33_RS01120 (JYG33_01120)	242823..243254	-	432	WP_207873791.1	flagellar export chaperone FliS	-
JYG33_RS01125 (JYG33_01125)	243261..244649	-	1389	WP_207873792.1	flagellar filament capping protein FliD	-
JYG33_RS01130 (JYG33_01130)	244739..245140	-	402	WP_207873793.1	flagellar protein FlaG	-
JYG33_RS01135 (JYG33_01135)	245379..246140	+	762	WP_207873794.1	RNA polymerase sigma factor FliA	-
JYG33_RS01140 (JYG33_01140)	246275..246526	+	252	WP_207873795.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
JYG33_RS01145 (JYG33_01145)	246513..246842	+	330	WP_207873796.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
JYG33_RS01150 (JYG33_01150)	246930..250082	-	3153	WP_207873797.1	hypothetical protein	-
JYG33_RS01155 (JYG33_01155)	250242..251318	-	1077	WP_207873798.1	FliC/FljB family flagellin	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (13-92)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (9-77)

Sequences

Toxin

Protein

• Length: 110 a.a.
• Molecular weight: 12531.62 Da
• Isoelectric Point: 10.0714

>T194875 WP_207873796.1 NZ_CP070975:246513-246842 [Alcaligenes sp. SORT26]
MTSSDRAPTKYKLKFLPEALQEWARLDGSVKTTFKSLLRKRLDVPHVPGSALRGDLQHCYKIKLLKQGYRLVYTVEDDVL
VVLVLAVDKREDMAAYRAAVQRLSENLER

Nucleotide

• Length: 330 bp

>T194875 NZ_CP094144:18496-19245 [Helicobacter pylori]
ATGGAAACTAAAGAAGAAGATAAAGATAAAAAGCTAGAAAAAATTATTGTATTGCTGTGCGAAGAGGGGGATTTGTCTAG
TCAAAAAGATCAAATCATCAAAGATCTCAAAGAAATCTATGAAGGAGAATACAAGCATAAATACTCAAAAATCACAACTA
TTATTTTAAATTCCACAATGGATAAAGAGCAAGCCTTTATGATGCTCACACAAAATATAAAGACACTCAAAGAGATTCAA
GATAATAAAGAAGTTGAAAGCATTAAACCAAAACTAGAAAAGCTTTATGATCACATGAATTTAGAGTGTATCAGACTGCA
AGATTTTGATGAGAAAATGAGTAGAGTTAAAGATGTTTCTATAAAGTTAGAAGATGAACTAAATAAAAACTATAAAAAAT
TAAGCGAAGAATTGAATAAGCAACAAACACAATACATAACAATTCTAGGTATTTTTGCCTCTATTGTTTTAACATTTGTT
GGGGGATTGGCGTTTTCCACTTCTGTTTTATCAAATATTGACAAAGCGAACGCCTATCGTTTGGTTTTTGTTATGGCTTT
TATAGCTTTATTTTTTGGGAATATTTTGTATCTGCTTTTTTCTTTTTTATCAAAAATATCCTTATCATCAAAAATATCCT
TATCAAAAGAGGAAAGAGATAAACAAGAAAATTTTTTCAAAAAACCTATTTTTTGGTTTAATCTAATGGTTACAATTCTA
TTTGTGATTGGTTTTGTGGGAGAGAATTGA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9477.88 Da
• Isoelectric Point: 5.0916

>AT194875 WP_207873795.1 NZ_CP070975:246275-246526 [Alcaligenes sp. SORT26]
MDAIYADYSISMSEFKKNPAQVLRTAGEKPVAVLNHNRPAFYMVTPRLFEALVEEIANRDLNELVRRRLAVKDTAVEVDL
DQL

Nucleotide

• Length: 252 bp

>AT194875 NZ_CP094144:18069-18506 [Helicobacter pylori]
ATGGTCAATGCTTTGGAACTAGCAAAATATATTCTTAAGCATTCAAACAAAGAATTGAGCAACTTAGAATTGCAAAAAAC
TTTGTATTTCACAGAGCTTGACTATATCAAAAAGTTTGACAAACACCTAGTTTCTGATGATTTTGAAGCTTGGAAATATG
GGCCTGTTGCAAGGGAAGTGTATTATGAATACCGCAATTATGGTGCCAATTCCATTGATAAACCCAAAGAAGAAACGCTC
TCACAAGATCTTAGAAAAGATGAATTGGAAACCATCAACTACTCCATAGAAAAATGCAACGAAAAATCCTATTGGGATTT
AGTGAAAGAGAGTCATAAAGAAGATGGCGCTTGGCATAAAAGCTTCAAAGAAGATAGAAAAGAAGTCATTAGCAAAGATT
TGATCAAACAAGAAGCAAAACAAGCAAATGGAAACTAA