194852

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 3218874..3219541 Replicon chromosome
Accession NZ_CP070968
Organism Brevundimonas sp. CS1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JX001_RS15720 Protein ID WP_205681720.1
Coordinates 3219098..3219541 (+) Length 148 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JX001_RS15715 Protein ID WP_205681719.1
Coordinates 3218874..3219101 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JX001_RS15695 3214509..3215354 - 846 WP_165118315.1 tol-pal system protein -
JX001_RS15700 3215396..3216535 - 1140 WP_205681718.1 DUF3667 domain-containing protein -
JX001_RS15705 3216663..3217226 - 564 WP_055753951.1 peptidoglycan-associated lipoprotein Pal -
JX001_RS15710 3217368..3218732 - 1365 WP_112861281.1 Tol-Pal system protein TolB -
JX001_RS15715 3218874..3219101 + 228 WP_205681719.1 CopG family transcriptional regulator Antitoxin
JX001_RS15720 3219098..3219541 + 444 WP_205681720.1 VapC toxin family PIN domain ribonuclease Toxin
JX001_RS15725 3219538..3220416 - 879 WP_205681721.1 hypothetical protein -
JX001_RS15730 3220422..3220874 - 453 WP_205681722.1 protein TolR -
JX001_RS15735 3220878..3221630 - 753 WP_205681723.1 protein TolQ -
JX001_RS15740 3221771..3222205 - 435 WP_205681724.1 hypothetical protein -
JX001_RS15745 3222233..3222691 - 459 WP_205683223.1 tol-pal system-associated acyl-CoA thioesterase -
JX001_RS15750 3222697..3223560 - 864 WP_205681725.1 hypothetical protein -
JX001_RS15755 3223557..3223934 - 378 WP_205681726.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain toxin

(1-133)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 148 a.a.        Molecular weight: 15989.25 Da        Isoelectric Point: 5.4710

>T194852 WP_205681720.1 NZ_CP070968:3219098-3219541 [Brevundimonas sp. CS1]
MTYLLDVNVLIALVDPRHVFHDTANIWFQREAVSSWATCPITENGLVRIVGNSRYRNPVGTPFEVIGTLNLLRDMPGHVF
WPDTLSLADASVFDGSAITTPEQVTDAYLLGLAVSNGGLLATFDRRLSPQAVIGGRDALHLIAPPHA

Download         Length: 444 bp

>T194852 NZ_CP094129:576828-577100 [Helicobacter pylori]
ATGCTGATGATTGAAACCAGTAAAAAATTTGATAAGGATCTTAAAATTCTTGTTAAAAACGGGTTTGATTTAAAGCTTTT
ATATAAAGTGGTTGAAAATTTAGCCAAAGAGCAACCCCTAGATCCCAAATACAAAGACCACCCGCTCAAAGGCGCTTTAA
AAGATTTTAGGGAATGCCACATTAAACCTGATATTTTGCTTGTCTATCAAATTAAAAAACAAGAAAACACCCTCTTTTTA
GTAAGGTTAGGCAGTCATAGCGAGCTGTTTTAA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8315.52 Da        Isoelectric Point: 5.0176

>AT194852 WP_205681719.1 NZ_CP070968:3218874-3219101 [Brevundimonas sp. CS1]
MRTTLAIDDDVLNAARAIAVHQDRTIGEVVSELARQALQKRPTTVRFRDGVPLLPDRPGPMVTLEDVNALRDELP

Download         Length: 228 bp

>AT194852 NZ_CP094129:576530-576841 [Helicobacter pylori]
ATGCCTAACTCTCCCACCAAAAAAGACTACACACAATACAGCGAAAAACAGCTTTTTAACTTTTTAAATTCTATTAAGAC
CAAACAAAAAAGAGCGTTAGAAAAATTGAAAGAAATCCAAGCTCAAAAACAAAGAATCAAAAAAGCGCTCCAATTTAAAG
CGCTCCATTTAACCGAAAACGGATACACCATAGAAGAAGAGCGAGAAATCTTAGCAAGGGCTAAAGACACCAAGAACCAC
CTTTGTTTTAAAAATATAGAGGATTTTAAAAAGCATTGTGAAAACTTAAGATTTAAAAATGCTGATGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References