Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 3113633..3114195 Replicon chromosome
Accession NZ_CP070968
Organism Brevundimonas sp. CS1

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag JX001_RS15150 Protein ID WP_205681643.1
Coordinates 3113884..3114195 (+) Length 104 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag JX001_RS15145 Protein ID WP_205681642.1
Coordinates 3113633..3113887 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JX001_RS15120 3108684..3108944 + 261 WP_205681637.1 Txe/YoeB family addiction module toxin -
JX001_RS15125 3108941..3109660 + 720 WP_205681638.1 16S rRNA (uracil(1498)-N(3))-methyltransferase -
JX001_RS15130 3109796..3111157 + 1362 WP_205681639.1 glutamate--cysteine ligase -
JX001_RS15135 3111154..3111897 - 744 WP_205681640.1 hypothetical protein -
JX001_RS15140 3112007..3113578 + 1572 WP_205681641.1 response regulator -
JX001_RS15145 3113633..3113887 + 255 WP_205681642.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
JX001_RS15150 3113884..3114195 + 312 WP_205681643.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JX001_RS15155 3114192..3114941 + 750 WP_205681644.1 DUF72 domain-containing protein -
JX001_RS15160 3115023..3116078 + 1056 WP_205683216.1 alcohol dehydrogenase catalytic domain-containing protein -
JX001_RS15165 3116222..3116947 + 726 WP_066549787.1 acetoacetyl-CoA reductase -
JX001_RS15170 3116997..3117764 + 768 WP_205681645.1 DUF4908 domain-containing protein -
JX001_RS15175 3117922..3118644 - 723 WP_205681646.1 hydroxyacylglutathione hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-92)

Antitoxin

Antitoxin ParD

(3-70)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 11758.10 Da        Isoelectric Point: 4.8888

>T194850 WP_205681643.1 NZ_CP070968:3113884-3114195 [Brevundimonas sp. CS1]
MSGYRLSKEASEDLVAIYIQGHDQFGPRQADGYLDELDALFRRLAASPGMARLRLEYDPPIRVFAFKAHVIIYDQEQDGV
LIQRVRHGHEDWQGATGDERSEP

Download         Length: 312 bp

>T194850 NZ_CP094128:20711-21493 [Helicobacter pylori]
ATGGAAACTAAAGAAGAGGATAAAGATAAAAAGCTAGAAGAAATTATTGTATTGCTGTGCGAAGAGGGGGATTTGTCTAG
CCAAAAAGATCAAATCATCAAAGATCTCAAAGAAATCTATAAAGGAGAATACAAGCATAAATACTCAAAAATCACAACTA
TTATTTTAAATTCCACAAGGGATAAAGAGCAAGCCTTTATGATGCTCACACAAAATATAAAGACGCTCAAAGAGATTCAA
GATAATAAAGAAGTTGAAAGCATTAAAACAAAACTAGAAAAGCTTTATGATCACATGAATTTAGAGTGTATCAGACTGCA
AGATTTTGATGAGAAAATGAGTAGAGTTAAAGATGTTTCTATAAAGTTAGAAGATGAACTAAATAAAAACTATAAAAAAT
TAAGCGAAGAATTGAATAGGCAACAAACACAATACATAACAATTCTAGGTATTTTTGCCTCTATTGTTTTAACATTTGTT
GGGGGATTGGCGTTTTCCACTTCTGTTTTATCAAATATTGACAAAGCGAACGCCTATCGTTTGGTTTTTGTTATGGCTTT
TATAGCTTTATTTTTTGGGAATATTTTGTATCTGCTTTTTTCTTTTTTATCAAAAATATCCTTATCATCAAAAATATCCT
TATCAAAAGAGGAAAGAGATAAACAAGAAAATTTTTTCAAAAAACCTATTTTTTGGCTTAATCTAATGGTTACAATTCTA
TTTGTGATTGGTTTTTTTGGAGAATTGCATATAATACAAAGATTAGTTTCTAAATATCTTTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9447.87 Da        Isoelectric Point: 10.3437

>AT194850 WP_205681642.1 NZ_CP070968:3113633-3113887 [Brevundimonas sp. CS1]
MATMNISLPDPMKAWVEEQAKSGRYANTSDVVRDLIRREQVKAEKIANMQRLIDEGRASGISQMTMADIRAEALSRIAAR
RKAE

Download         Length: 255 bp

>AT194850 NZ_CP094128:20284-20721 [Helicobacter pylori]
ATGGTCAATACTTTGGAATTAGCAAAATATATTCTTAAGCATTCCAACAAAGAATTGAGCAACTTAGAATTGCAAAAAAC
TTTGTATTTCACAGAGCTTGACTATATCAAAAAGTTTGACAAACACCTAGTTTCTGATGATTTTGAAGCTTGGAAATACG
GGCCTGTTGCAAGAGAAGTGTATTATGAATATCGCAATTACGGCGCCAATTCTATTGACAAACCTAAAGAAGAAACGCTC
TCACAAAATCTTAGAGAAGATGAACTTGAAACCATCAATCGCTCCATAAAAAAATGCAACGAAAAATCCTATTGGGATTT
AGTGAAGGAGAGTCATAAAGAAGATGGTGCTTGGCATAAAAGCTTCAAAGAAGATAGAAAAGAAATCATTAGCAAAGATT
TGATCAAACAAGAAGCAAAACAAGCAAATGGAAACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References