Detailed information of TA system TA194847

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): TsaAT/-
• Location: 1881997..1882459
• Replicon: chromosome
• Accession: NZ_CP070964
• Organism: Staphylococcus sp. SB1-57

Toxin (Protein)

• Gene name: TsaT
• Uniprot ID: -
• Locus tag: JX000_RS09325
• Protein ID: WP_124228472.1
• Coordinates: 1882274..1882459 (+)
• Length: 62 a.a.

Antitoxin (Protein)

• Gene name: TsaA
• Uniprot ID: -
• Locus tag: JX000_RS09320
• Protein ID: WP_002450867.1
• Coordinates: 1881997..1882254 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JX000_RS09280	1877251..1877574	+	324	WP_002450859.1	thioredoxin family protein	-
JX000_RS09285	1877683..1878222	-	540	WP_002465937.1	nitroreductase	-
JX000_RS09290	1878300..1879016	-	717	WP_002450861.1	type I 3-dehydroquinate dehydratase	-
JX000_RS09295	1879194..1879616	+	423	WP_002450862.1	organic hydroperoxide resistance protein	-
JX000_RS09300	1879899..1880393	+	495	WP_002450863.1	GNAT family N-acetyltransferase	-
JX000_RS09305	1880523..1881113	-	591	WP_206140650.1	histidine phosphatase family protein	-
JX000_RS09310	1881314..1881547	+	234	WP_002450865.1	hypothetical protein	-
JX000_RS09315	1881539..1881742	-	204	WP_002450866.1	sterile alpha motif-like domain-containing protein	-
JX000_RS09320	1881997..1882254	+	258	WP_002450867.1	hypothetical protein	Antitoxin
JX000_RS09325	1882274..1882459	+	186	WP_124228472.1	hypothetical protein	Toxin
JX000_RS09330	1882559..1883140	+	582	WP_124228473.1	hypothetical protein	-
JX000_RS09335	1883201..1883434	-	234	WP_206140651.1	hypothetical protein	-
JX000_RS09340	1883698..1884450	+	753	WP_206140652.1	poly-gamma-glutamate hydrolase family protein	-
JX000_RS09345	1884540..1884824	+	285	WP_002450872.1	hypothetical protein	-
JX000_RS09350	1884902..1885117	+	216	WP_107532346.1	hypothetical protein	-
JX000_RS09355	1885585..1885824	+	240	WP_002450874.1	hypothetical protein	-
JX000_RS09360	1886053..1886286	+	234	WP_002450875.1	hypothetical protein	-
JX000_RS09365	1886460..1886660	-	201	WP_002450876.1	cold-shock protein	-
JX000_RS09370	1886980..1887345	-	366	WP_124228474.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (3-92)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 62 a.a.
• Molecular weight: 6977.68 Da
• Isoelectric Point: 10.1605

>T194847 WP_124228472.1 NZ_CP070964:1882274-1882459 [Staphylococcus sp. SB1-57]
MSLHFTILFWLSVIFIIAGAIILAIMLKTKKESKKESYLGFTIVFFIFGLAMLIYTLLFGL

Nucleotide

• Length: 186 bp

>T194847 NZ_CP094122:530222-530545 [Helicobacter pylori]
ATGCTTAAAGTCAGAACCAAGAAAGATTTTCTTAAAGACTTTAATAAGCATATCTTATCTGGGCGTATTACAGAAAGCGA
TGTTACAAGCGTTGTTGATTGTCTCAAAGAGCAAAAACCACTCCAACAAAAATATTGCGATCATGCCTTGAGCGGCAATC
TTAAAGGGTTGAGAGAGTGTCATGTTAAGCCAAACTTGTTATTGATTTATGAAATCAAAAAACAAGAAAACGAACTTGTT
TTATTGCGTCTAGACACTCATAGCGAGCTATTTAAAAAGCGATCAAACACTAAAAAATTTATCTACAACAACAATCCGTG
CTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9976.25 Da
• Isoelectric Point: 4.6285

>AT194847 WP_002450867.1 NZ_CP070964:1881997-1882254 [Staphylococcus sp. SB1-57]
MKRYILHAINIILTILLIIFNVIITYNTNLDETLWLVPGLIVCGLIMMISFTIAITIKDLLSEVLFFINIILTLYYIYPI
FYDFL

Nucleotide

• Length: 258 bp

>AT194847 NZ_CP094122:529915-530229 [Helicobacter pylori]
ATGTCAAATATTATTACAGATTACTCGCAATACAATGAAAAGCAACTGCACAATTTCTTAAACACCATTGAAAAACAATT
GCTTAAGGCAGAAGGGGATAAAAATAAGGCGATAAAAAAAATCCAAGAGTGTGAATTGCAAGAACAAATGATCAGACAAG
TTTTAGCCCAAAAACATTCTCAAGAAAAAGAACCCACACAAAGTTTGTTAAATACGATCGCCTCAAAAGATGACCCAGAA
TACGATGTTTCGTTTGGAGATTTCAATGATTTTTTACAAATAGCAAAACAAGAAAGAGAAAGGCATAATGCTTAA