194841

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsdAT/-
Location 780948..781419 Replicon chromosome
Accession NZ_CP070964
Organism Staphylococcus sp. SB1-57

Toxin (Protein)


Gene name TsdT Uniprot ID -
Locus tag JX000_RS03825 Protein ID WP_206140901.1
Coordinates 781252..781419 (+) Length 56 a.a.

Antitoxin (Protein)


Gene name TsdA Uniprot ID -
Locus tag JX000_RS03820 Protein ID WP_002451638.1
Coordinates 780948..781241 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JX000_RS03795 776070..776861 + 792 WP_002451643.1 hydroxyethylthiazole kinase -
JX000_RS03800 776862..777503 + 642 WP_206140899.1 thiamine phosphate synthase -
JX000_RS03805 777592..778461 + 870 WP_002451641.1 membrane protein insertase YidC -
JX000_RS03810 778501..779145 - 645 WP_206140900.1 HD domain-containing protein -
JX000_RS03815 779275..780759 - 1485 WP_124227716.1 cardiolipin synthase -
JX000_RS03820 780948..781241 + 294 WP_002451638.1 copper-sensing transcriptional repressor CsoR Antitoxin
JX000_RS03825 781252..781419 + 168 WP_206140901.1 heavy-metal-associated domain-containing protein Toxin
JX000_RS03830 781598..781735 + 138 WP_002451636.1 hypothetical protein -
JX000_RS03835 781878..783068 - 1191 WP_049425344.1 rod shape-determining protein RodA -
JX000_RS03840 783427..784497 + 1071 WP_206140902.1 D-alanine--D-alanine ligase -
JX000_RS03845 784513..785874 + 1362 WP_206140903.1 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Metal-sensitive transcriptional repressor

(14-92)


Sequences

Toxin        


Download         Length: 56 a.a.        Molecular weight: 6113.84 Da        Isoelectric Point: 3.7141

>T194841 WP_206140901.1 NZ_CP070964:781252-781419 [Staphylococcus sp. SB1-57]
VQQKIVYTAGIETQEQSESVKNLLTEMIGVYQVEIDINTGNISIEFETPANLNSI

Download         Length: 168 bp

>T194841 NZ_CP094119:c1105618-1105352 [Helicobacter pylori]
GTGTTGAAACTCAACCTTAAAAAATCTTTTCAAAAAGATTTTGATAAATTACTTTTGAATGGGTTTGATGATAGCGTTTT
GAATGAAGTCATTCTAACCTTAAGAAAGAAAGAACCGCTAGACCCACAATTTAAAGATCATGCTTTAAAAGGCAATTGGA
AGCCTTTTAGAGAATGCCATATCAAAGCTGATATTTTGCTTGTGTATTTAGTGAAAGATGATGAGCTTATTTTAGTAAGG
TTAGGCAGTCATAGCGAGCTGTTTTAA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 11159.63 Da        Isoelectric Point: 6.3270

>AT194841 WP_002451638.1 NZ_CP070964:780948-781241 [Staphylococcus sp. SB1-57]
VTEQDHAHHSEQSKANLKSRLNRIEGQVRAINRMIEEDVYCDDVLTQIRATRSALNSVATKLLEQHMKSCIAEKVNQGHQ
EEAMEELLVTFQKLMKD

Download         Length: 294 bp

>AT194841 NZ_CP094119:c1105976-1105599 [Helicobacter pylori]
ATGCCTAACTCTCCCACCAAAAAAGACTACACACGATACAGCGAAAAACAGCTTTTTAGCTTAATCAATCAATTAGAGCA
AAAAATCAAAAAGATGCAAAATGATAGAGCTTCTTTTAAAGAAAAAATGGCTAAAGAATTGGAAAAAAGGGATCAAAACT
TTAAGGATAAAATAGACGCATTAAATAAACTCTTGCAAAAAATCAGCCAAGCTTTTGGTGATAAAAGAGATTGTTGTTTG
GGGCGCAAGATCCCAAACCTTGAAACGCAACAAGCCATGAGAGATGCGCTTAACAAAGAAACCGATTTGATTGTTGAGGA
TTTTTCTAGTTATAGCGATGAAAGAAAAAGGGCGTTAGGTGTTGAAACTCAACCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References