Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) TsdAT/-
Location 780948..781419 Replicon chromosome
Accession NZ_CP070964
Organism Staphylococcus sp. SB1-57

Toxin (Protein)


Gene name TsdT Uniprot ID -
Locus tag JX000_RS03825 Protein ID WP_206140901.1
Coordinates 781252..781419 (+) Length 56 a.a.

Antitoxin (Protein)


Gene name TsdA Uniprot ID -
Locus tag JX000_RS03820 Protein ID WP_002451638.1
Coordinates 780948..781241 (+) Length 98 a.a.

Genomic Context


JX000_RS03795JX000_RS03800JX000_RS03805JX000_RS03820JX000_RS03825JX000_RS03830JX000_RS03840JX000_RS03845JX000_RS03810JX000_RS03815JX000_RS03835
Location: 776070..776861 (792 bp)
Type: Others
Protein ID: WP_002451643.1
Location: 776862..777503 (642 bp)
Type: Others
Protein ID: WP_206140899.1
Location: 777592..778461 (870 bp)
Type: Others
Protein ID: WP_002451641.1
Location: 780948..781241 (294 bp)
Type: Antitoxin
Protein ID: WP_002451638.1
Location: 781252..781419 (168 bp)
Type: Toxin
Protein ID: WP_206140901.1
Location: 781598..781735 (138 bp)
Type: Others
Protein ID: WP_002451636.1
Location: 783427..784497 (1071 bp)
Type: Others
Protein ID: WP_206140902.1
Location: 784513..785874 (1362 bp)
Type: Others
Protein ID: WP_206140903.1
Location: 778501..779145 (645 bp)
Type: Others
Protein ID: WP_206140900.1
Location: 779275..780759 (1485 bp)
Type: Others
Protein ID: WP_124227716.1
Location: 781878..783068 (1191 bp)
Type: Others
Protein ID: WP_049425344.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
JX000_RS03795776070..776861+792WP_002451643.1hydroxyethylthiazole kinase-
JX000_RS03800776862..777503+642WP_206140899.1thiamine phosphate synthase-
JX000_RS03805777592..778461+870WP_002451641.1membrane protein insertase YidC-
JX000_RS03810778501..779145-645WP_206140900.1HD domain-containing protein-
JX000_RS03815779275..780759-1485WP_124227716.1cardiolipin synthase-
JX000_RS03820780948..781241+294WP_002451638.1copper-sensing transcriptional repressor CsoRAntitoxin
JX000_RS03825781252..781419+168WP_206140901.1heavy-metal-associated domain-containing proteinToxin
JX000_RS03830781598..781735+138WP_002451636.1hypothetical protein-
JX000_RS03835781878..783068-1191WP_049425344.1rod shape-determining protein RodA-
JX000_RS03840783427..784497+1071WP_206140902.1D-alanine--D-alanine ligase-
JX000_RS03845784513..785874+1362WP_206140903.1UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

(14-92)


Sequences


Toxin        


Download         Length: 56 a.a.        Molecular weight: 6113.84 Da        Isoelectric Point: 3.7141

>T194841 WP_206140901.1 NZ_CP070964:781252-781419 [Staphylococcus sp. SB1-57]
VQQKIVYTAGIETQEQSESVKNLLTEMIGVYQVEIDINTGNISIEFETPANLNSI

Download         Length: 168 bp

>T194841 NZ_CP094119:c1105618-1105352 [Helicobacter pylori]
GTGTTGAAACTCAACCTTAAAAAATCTTTTCAAAAAGATTTTGATAAATTACTTTTGAATGGGTTTGATGATAGCGTTTT
GAATGAAGTCATTCTAACCTTAAGAAAGAAAGAACCGCTAGACCCACAATTTAAAGATCATGCTTTAAAAGGCAATTGGA
AGCCTTTTAGAGAATGCCATATCAAAGCTGATATTTTGCTTGTGTATTTAGTGAAAGATGATGAGCTTATTTTAGTAAGG
TTAGGCAGTCATAGCGAGCTGTTTTAA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 11159.63 Da        Isoelectric Point: 6.3270

>AT194841 WP_002451638.1 NZ_CP070964:780948-781241 [Staphylococcus sp. SB1-57]
VTEQDHAHHSEQSKANLKSRLNRIEGQVRAINRMIEEDVYCDDVLTQIRATRSALNSVATKLLEQHMKSCIAEKVNQGHQ
EEAMEELLVTFQKLMKD

Download         Length: 294 bp

>AT194841 NZ_CP094119:c1105976-1105599 [Helicobacter pylori]
ATGCCTAACTCTCCCACCAAAAAAGACTACACACGATACAGCGAAAAACAGCTTTTTAGCTTAATCAATCAATTAGAGCA
AAAAATCAAAAAGATGCAAAATGATAGAGCTTCTTTTAAAGAAAAAATGGCTAAAGAATTGGAAAAAAGGGATCAAAACT
TTAAGGATAAAATAGACGCATTAAATAAACTCTTGCAAAAAATCAGCCAAGCTTTTGGTGATAAAAGAGATTGTTGTTTG
GGGCGCAAGATCCCAAACCTTGAAACGCAACAAGCCATGAGAGATGCGCTTAACAAAGAAACCGATTTGATTGTTGAGGA
TTTTTCTAGTTATAGCGATGAAAGAAAAAGGGCGTTAGGTGTTGAAACTCAACCTTAA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References