Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1640788..1641059 Replicon chromosome
Accession NZ_CP070962
Organism Escherichia coli strain K-12 J53

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1640918..1641021 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1640788..1641059 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JTR57_RS07915 1637343..1638005 - 663 WP_000944256.1 exodeoxyribonuclease X -
JTR57_RS07920 1638029..1638685 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
JTR57_RS07925 1638787..1639017 - 231 WP_000916763.1 DNA polymerase III subunit theta -
JTR57_RS07930 1639156..1639530 + 375 WP_000168747.1 CopC domain-containing protein YobA -
JTR57_RS07935 1639534..1640406 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
JTR57_RS07940 1640419..1640760 + 342 WP_000976476.1 YebY family protein -
- 1640788..1641059 - 272 - - Antitoxin
- 1640918..1641021 + 104 - - Toxin
JTR57_RS07945 1641156..1641812 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
JTR57_RS07950 1641813..1642004 - 192 WP_000457842.1 YebW family protein -
JTR57_RS07955 1642109..1642345 - 237 WP_001295499.1 YebV family protein -
JTR57_RS07960 1642463..1643902 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T194808 NZ_CP070962:1640918-1641021 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT194808 NZ_CP070962:c1641059-1640788 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References