Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2594986..2595253 Replicon chromosome
Accession NZ_CP070954
Organism Escherichia fergusonii strain EF44

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2595024..2595127 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2594986..2595253 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JYG65_RS12360 2592143..2593582 + 1440 WP_223666645.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
JYG65_RS12365 2593701..2593937 + 237 WP_001295499.1 YebV family protein -
JYG65_RS12370 2594042..2594233 + 192 WP_001296140.1 YebW family protein -
JYG65_RS12375 2594234..2594890 - 657 WP_223666644.1 protein-serine/threonine phosphatase -
- 2594986..2595253 + 268 - - Antitoxin
- 2595024..2595127 - 104 - - Toxin
JYG65_RS12380 2595283..2595624 - 342 WP_000976177.1 YebY family protein -
JYG65_RS12385 2595636..2596508 - 873 WP_181198936.1 copper homeostasis membrane protein CopD -
JYG65_RS12390 2596511..2596885 - 375 WP_000168725.1 CopC domain-containing protein YobA -
JYG65_RS12395 2597024..2597254 + 231 WP_000700614.1 DNA polymerase III subunit theta -
JYG65_RS12400 2597361..2598017 + 657 WP_000075607.1 carbon-nitrogen hydrolase family protein -
JYG65_RS12405 2598041..2598703 + 663 WP_000946659.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T194763 NZ_CP070954:c2595127-2595024 [Escherichia fergusonii]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 268 bp

>AT194763 NZ_CP070954:2594986-2595253 [Escherichia fergusonii]
AAAGTCAGCGAAGGGAATTTTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGT
TCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References