Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1996989..1997260 Replicon chromosome
Accession NZ_CP070920
Organism Escherichia coli strain 40EC

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1997119..1997222 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1996989..1997260 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JR909_RS09610 1993973..1994209 - 237 Protein_1874 exodeoxyribonuclease X -
JR909_RS09615 1994230..1994886 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
JR909_RS09620 1994988..1995218 - 231 WP_000916763.1 DNA polymerase III subunit theta -
JR909_RS09625 1995357..1995731 + 375 WP_000204699.1 CopC domain-containing protein YobA -
JR909_RS09630 1995735..1996607 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
JR909_RS09635 1996620..1996961 + 342 WP_000976492.1 YebY family protein -
- 1996989..1997260 - 272 - - Antitoxin
- 1997119..1997222 + 104 - - Toxin
JR909_RS09640 1997357..1998013 + 657 WP_000812712.1 protein-serine/threonine phosphatase -
JR909_RS09645 1998014..1998205 - 192 WP_001296140.1 YebW family protein -
JR909_RS09650 1998310..1998546 - 237 WP_001295499.1 DUF1480 family protein -
JR909_RS09655 1998664..2000103 - 1440 WP_000057023.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T194671 NZ_CP070920:1997119-1997222 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT194671 NZ_CP070920:c1997260-1996989 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References