Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1881889..1882034 Replicon chromosome
Accession NZ_CP070898
Organism Klebsiella pneumoniae strain JNQH116

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1881925..1882027 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1881889..1882034 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JYA99_RS09040 1877019..1879079 + 2061 WP_004151449.1 oligopeptidase B -
JYA99_RS09045 1879083..1879742 - 660 WP_002911407.1 exodeoxyribonuclease X -
JYA99_RS09050 1879821..1880051 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JYA99_RS09055 1880164..1880538 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JYA99_RS09060 1880542..1881411 + 870 WP_048331959.1 copper homeostasis membrane protein CopD -
JYA99_RS09065 1881428..1881766 + 339 WP_016529031.1 YebY family protein -
- 1881889..1882034 - 146 - - Antitoxin
- 1881925..1882027 + 103 - - Toxin
JYA99_RS09070 1882403..1882546 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JYA99_RS09075 1882651..1883619 - 969 WP_074185275.1 DUF535 family protein -
JYA99_RS09080 1883776..1884429 + 654 WP_032447686.1 protein-serine/threonine phosphatase -
JYA99_RS09085 1884426..1884617 - 192 WP_002911395.1 YebW family protein -
JYA99_RS09090 1884715..1884954 - 240 WP_002911393.1 YebV family protein -
JYA99_RS09095 1885070..1886503 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T194576 NZ_CP070898:1881925-1882027 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT194576 NZ_CP070898:c1882034-1881889 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References