Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1979414..1979559 | Replicon | chromosome |
| Accession | NZ_CP070890 | ||
| Organism | Klebsiella pneumoniae strain KP-135LU | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1979450..1979552 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1979414..1979559 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HZC98_RS09530 | 1974544..1976604 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| HZC98_RS09535 | 1976608..1977267 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| HZC98_RS09540 | 1977346..1977576 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| HZC98_RS09545 | 1977689..1978063 | + | 375 | WP_039819395.1 | CopC domain-containing protein YobA | - |
| HZC98_RS09550 | 1978067..1978936 | + | 870 | WP_004175431.1 | copper homeostasis membrane protein CopD | - |
| HZC98_RS09555 | 1978953..1979291 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 1979414..1979559 | - | 146 | - | - | Antitoxin |
| - | 1979450..1979552 | + | 103 | - | - | Toxin |
| HZC98_RS09560 | 1979928..1980071 | - | 144 | WP_038431282.1 | Ecr family regulatory small membrane protein | - |
| HZC98_RS09565 | 1980176..1981144 | - | 969 | WP_014907334.1 | VirK/YbjX family protein | - |
| HZC98_RS09570 | 1981301..1981954 | + | 654 | WP_024622748.1 | protein-serine/threonine phosphatase | - |
| HZC98_RS09575 | 1981951..1982142 | - | 192 | WP_002911395.1 | YebW family protein | - |
| HZC98_RS09580 | 1982240..1982479 | - | 240 | WP_002911393.1 | YebV family protein | - |
| HZC98_RS09585 | 1982595..1984028 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T194553 NZ_CP070890:1979450-1979552 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT194553 NZ_CP070890:c1979559-1979414 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT