Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 457039..457688 Replicon chromosome
Accession NZ_CP070866
Organism Acinetobacter johnsonii strain XY27

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag JW980_RS02295 Protein ID WP_205667573.1
Coordinates 457302..457688 (+) Length 129 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID N9CU98
Locus tag JW980_RS02290 Protein ID WP_004977895.1
Coordinates 457039..457296 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JW980_RS02270 452658..453023 + 366 WP_004691290.1 50S ribosomal protein L17 -
JW980_RS02275 453219..454709 + 1491 WP_205667571.1 NAD(P)-binding protein -
JW980_RS02280 454848..455639 + 792 WP_130235026.1 alpha/beta hydrolase -
JW980_RS02285 455674..456846 - 1173 WP_205667572.1 acyl-CoA dehydrogenase family protein -
JW980_RS02290 457039..457296 + 258 WP_004977895.1 succinate dehydrogenase assembly factor 2 Antitoxin
JW980_RS02295 457302..457688 + 387 WP_205667573.1 hypothetical protein Toxin
JW980_RS02300 458210..459247 + 1038 WP_004977889.1 hypothetical protein -
JW980_RS02305 459319..459891 + 573 WP_010327586.1 rhombosortase -
JW980_RS02310 460074..462356 + 2283 WP_205667574.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(5-127)

Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 15266.25 Da        Isoelectric Point: 10.4419

>T194521 WP_205667573.1 NZ_CP070866:457302-457688 [Acinetobacter johnsonii]
MEHRHFQLKPSRLAYVFQLSIYAVLMLVLYQLLPLGLWPIALVAGFVLYLFFLRGPQHLQLQHLDGRDWSLSLQKQTNVQ
RVQISHIVDHRAYIVIYFQHFRAKPMLVWCDQLPITQWKALKILTKMQ

Download         Length: 387 bp

>T194521 NZ_CP093548:c383124-383017 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10181.71 Da        Isoelectric Point: 4.7119

>AT194521 WP_004977895.1 NZ_CP070866:457039-457296 [Acinetobacter johnsonii]
MTEEMSLEERKVIYRARRGLKEIDVYFDPYVKNYYLQADPAEKAMFAALVEQEDPDLLDWFMEVSEPPRPEMKTLIQKLK
HYVHG

Download         Length: 258 bp

>AT194521 NZ_CP093548:383177-383238 [Escherichia coli]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB N9CU98

References